Protein bioinformatics II

Main objective

In this practical we learn about computationally characterising small molecule binding sites in proteins using pocket detection and docking.

Learning objectives

• You will recap prior introductory knowledge on structural bioinformatics.

• You will learn algorithms used to predict protein pockets and structures of proteins bound to small molecules.

• You will learn about computational methods to predict the structures of protein-protein complexes.

• You will be able to predict pockets and ligand binding structures using current computational methodologies.