Protein bioinformatics I

General information

Main objective

In the lecture we will discuss bioinformatics methods applied to the study of protein post-translational regulation. The lecture notes are provided in moodle. In the practical section you will learn how to perform co-regulation analysis of proteomics data.

Learning objectives

• You will understand the difference between protein interactions mediated by “linear-motifs” and those that are not.

• You will know how to model the specificity of “linear-motif” binding domains based on training data.

• You will understand how protein kinase activity can be estimated from phosphoproteomics data.

• You understand how multi-omics data can be used to predict protein-protein interactions

• You can use multi-omics data to predict protein-protein interactions.