Sunagawa Lab Block Course Fall 2022: 551-1119-00L Microbial Community Genomics

Sunagawa Lab Block Course Fall 2022: 551-1119-00L Microbial Community Genomics#

General information#

  • Course dates: 08.11.2022 - 30.11.2022

    • Week 1: Tue 1:00PM - 4:30PM, Wed - Fri 8:30AM - 4:30PM

    • Week 2: Tue 1:00PM - 4:30PM, Wed - Fri 8:30AM - 4:30PM

    • Week 3: Tue 1:00PM - 4:30PM, Wed - Fri 8:30AM - 4:30PM

    • Week 4: Tue 1:00PM - 4:30PM, Wed - Wed 8:30AM - 4:30PM

  • Exam: 30.11.2021, 13:00 - 15:00

  • Presentations: 01.12.2021, 13:00 - 14:00

  • Tutors:

  • Technichal Support:

Useful resources#

Student Projects#

  • Project 1 (unassigned): Visualization of genomes with auxiliary data such as phylogenetic, metabolic, or environmental information

  • Project 2 (Mina): Diversity within a mOTU: exploring the coherence of all MAGs assigned to single mOTUs

  • Project 3 (Colin): Comparison of closely related MAGs with contrasting environmental patterns

  • Project 4 (unassigned): Relation between genome-level features and environmental conditions

  • Project 5 (unassigned): Relation between genetic- and genome-level features with bacterial growth rate

  • Project 6 (unassigned): Relationship between optimal temperature with bacterial growth rate

  • Project 7 (Pierce): Auxotrophy from MAG exploration: amino acid synthesis pathways and their distribution across biological groups

  • Project 8 (unassigned): Pathway reconstruction and niche estimation based on genome annotations

Find more details in the Project presentation

Data availability#

The main study used as reference of this course can be found here:

Agenda#

Week 1#

W1.1

08.11

13:00 - 14:30

Introductory lecture

W1.2

08.11

15:00 - 16:30

Setup infrastructure

W1.3

09.11

08:30 - 10:00

Lecture on genomics - I

W1.4

09.11

10:30 - 12:00

Lecture on genomics - II

W1.5

09.11

13:00 - 14:30

Introduction to R

W1.6

09.11

15:00 - 16:30

Data transformation with R: tidyverse

W1.7

10.11

08:30 - 10:00

Data visualization with R: ggplot2

W1.8

10.11

10:30 - 12:00

Lecture on metagenome-assembled genomes (MAGs)

W1.9

10.11

13:00 - 14:30

Hands-on (tutorial) on Metagenomics

W1.10

10.11

15:00 - 16:30

Hands-on (tutorial) on Metagenomics

W1.11

11.11

08:30 - 10:00

Hands-on (tutorial) on Metagenomics

W1.12

11.11

10:30 - 12:00

Introduction to the Ocean Microbiome Database (exercise)

W1.13

11.11

13:00 - 14:30

Introduction to the Ocean Microbiome Database (cont.)

W1.14

11.11

15:00 - 16:30

Introduction to the Ocean Microbiome Database (cont.)

Week 2#

W2.1

15.11

13:00 - 14:30

Lecture on Operational Taxonomic Units (mOTUs)

W2.2

15.11

15:00 - 16:30

Wrap-up and project planning

W2.3

16.11

08:30 - 10:00

Lecture on best practices for data/project/software management

W2.5

16.11

13:00 - 14:30

Student projects

W2.4

16.11

10:30 - 12:00

Student projects

W2.6

16.11

15:00 - 16:30

Student projects

W2.7

17.11

08:30 - 10:00

Student projects

W2.8

17.11

10:30 - 12:00

Student projects

W2.9

17.11

13:00 - 14:30

Student projects

W2.10

17.11

15:00 - 16:30

Student projects

W2.11

18.11

08:30 - 10:00

Student projects

W2.12

18.11

10:30 - 12:00

Student projects

W2.13

18.11

13:00 - 14:30

Present progress & Discussion

W2.14

18.11

15:00 - 16:30

Wrap-up and plan W3

Week 3#

W3.1

22.11

13:00 - 14:30

Student projects

W3.2

22.11

15:00 - 16:30

Student projects

W3.3

23.11

08:30 - 10:00

Student projects

W3.4

23.11

10:30 - 12:00

Student projects

W3.5

23.11

13:00 - 14:30

Student projects

W3.6

23.11

15:00 - 16:30

Student projects

W3.7

24.11

08:30 - 10:00

Student projects

W3.8

24.11

10:30 - 12:00

Student projects

W3.9

24.11

13:00 - 14:30

Student projects

W3.10

24.11

15:00 - 16:30

Student projects

W3.11

25.11

08:30 - 10:00

Lecture on report writing (check also the report example)

W3.12

25.11

10:30 - 12:00

Draft for project presentation

W3.13

25.11

13:00 - 14:00

Discussion on presentation draft

W3.14

25.11

14:00 - 16:30

Last analyses for projects

Week 4#

W4.1

29.11

13:00 - 14:30

Exam

W4.2

29.11

14:00 - 16:30

Prepare presentation

W4.3

30.11

08:30 - 10:00

Prepare presentation

W4.4

30.11

10:30 - 12:00

Prepare presentation

W4.5

30.11

13:00 - 15:00

Prepare presentation

W4.6

30.11

15:00 - 16:00

Presentations (15 min. presentation + 5 min. questions)

W4.7

30.11

16:30 - 16:30

BlockCourse wrap-up