Sunagawa Lab Block Course Fall 2022: 551-1119-00L Microbial Community Genomics

General information

  • Course dates: 08.11.2022 - 30.11.2022

    • Week 1: Tue 1:00PM - 4:30PM, Wed - Fri 8:30AM - 4:30PM

    • Week 2: Tue 1:00PM - 4:30PM, Wed - Fri 8:30AM - 4:30PM

    • Week 3: Tue 1:00PM - 4:30PM, Wed - Fri 8:30AM - 4:30PM

    • Week 4: Tue 1:00PM - 4:30PM, Wed - Wed 8:30AM - 4:30PM

  • Exam: 30.11.2021, 13:00 - 15:00

  • Presentations: 01.12.2021, 13:00 - 14:00

  • Tutors:

  • Technichal Support:

Useful resources

Student Projects

  • Project 1 (unassigned): Visualization of genomes with auxiliary data such as phylogenetic, metabolic, or environmental information

  • Project 2 (Mina): Diversity within a mOTU: exploring the coherence of all MAGs assigned to single mOTUs

  • Project 3 (Colin): Comparison of closely related MAGs with contrasting environmental patterns

  • Project 4 (unassigned): Relation between genome-level features and environmental conditions

  • Project 5 (unassigned): Relation between genetic- and genome-level features with bacterial growth rate

  • Project 6 (unassigned): Relationship between optimal temperature with bacterial growth rate

  • Project 7 (Pierce): Auxotrophy from MAG exploration: amino acid synthesis pathways and their distribution across biological groups

  • Project 8 (unassigned): Pathway reconstruction and niche estimation based on genome annotations

Find more details in the Project presentation

Data availability

The main study used as reference of this course can be found here:

Agenda

Week 1

W1.1

08.11

13:00 - 14:30

Introductory lecture

W1.2

08.11

15:00 - 16:30

Setup infrastructure

W1.3

09.11

08:30 - 10:00

Lecture on genomics - I

W1.4

09.11

10:30 - 12:00

Lecture on genomics - II

W1.5

09.11

13:00 - 14:30

Introduction to R

W1.6

09.11

15:00 - 16:30

Data transformation with R: tidyverse

W1.7

10.11

08:30 - 10:00

Data visualization with R: ggplot2

W1.8

10.11

10:30 - 12:00

Lecture on metagenome-assembled genomes (MAGs)

W1.9

10.11

13:00 - 14:30

Hands-on (tutorial) on Metagenomics

W1.10

10.11

15:00 - 16:30

Hands-on (tutorial) on Metagenomics

W1.11

11.11

08:30 - 10:00

Hands-on (tutorial) on Metagenomics

W1.12

11.11

10:30 - 12:00

Introduction to the Ocean Microbiome Database (exercise)

W1.13

11.11

13:00 - 14:30

Introduction to the Ocean Microbiome Database (cont.)

W1.14

11.11

15:00 - 16:30

Introduction to the Ocean Microbiome Database (cont.)

Week 2

W2.1

15.11

13:00 - 14:30

Lecture on Operational Taxonomic Units (mOTUs)

W2.2

15.11

15:00 - 16:30

Wrap-up and project planning

W2.3

16.11

08:30 - 10:00

Lecture on best practices for data/project/software management

W2.5

16.11

13:00 - 14:30

Student projects

W2.4

16.11

10:30 - 12:00

Student projects

W2.6

16.11

15:00 - 16:30

Student projects

W2.7

17.11

08:30 - 10:00

Student projects

W2.8

17.11

10:30 - 12:00

Student projects

W2.9

17.11

13:00 - 14:30

Student projects

W2.10

17.11

15:00 - 16:30

Student projects

W2.11

18.11

08:30 - 10:00

Student projects

W2.12

18.11

10:30 - 12:00

Student projects

W2.13

18.11

13:00 - 14:30

Present progress & Discussion

W2.14

18.11

15:00 - 16:30

Wrap-up and plan W3

Week 3

W3.1

22.11

13:00 - 14:30

Student projects

W3.2

22.11

15:00 - 16:30

Student projects

W3.3

23.11

08:30 - 10:00

Student projects

W3.4

23.11

10:30 - 12:00

Student projects

W3.5

23.11

13:00 - 14:30

Student projects

W3.6

23.11

15:00 - 16:30

Student projects

W3.7

24.11

08:30 - 10:00

Student projects

W3.8

24.11

10:30 - 12:00

Student projects

W3.9

24.11

13:00 - 14:30

Student projects

W3.10

24.11

15:00 - 16:30

Student projects

W3.11

25.11

08:30 - 10:00

Lecture on report writing (check also the report example)

W3.12

25.11

10:30 - 12:00

Draft for project presentation

W3.13

25.11

13:00 - 14:00

Discussion on presentation draft

W3.14

25.11

14:00 - 16:30

Last analyses for projects

Week 4

W4.1

29.11

13:00 - 14:30

Exam

W4.2

29.11

14:00 - 16:30

Prepare presentation

W4.3

30.11

08:30 - 10:00

Prepare presentation

W4.4

30.11

10:30 - 12:00

Prepare presentation

W4.5

30.11

13:00 - 15:00

Prepare presentation

W4.6

30.11

15:00 - 16:00

Presentations (15 min. presentation + 5 min. questions)

W4.7

30.11

16:30 - 16:30

BlockCourse wrap-up