LOCUS       TARA_SAMEA6035815_MAG_00000013-scaffold_116 6820 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  TARA_SAMEA6035815_MAG_00000013-scaffold_116.
ACCESSION   TARA_SAMEA6035815_MAG_00000013-scaffold_116
VERSION     TARA_SAMEA6035815_MAG_00000013-scaffold_116
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2023-03-04 21:21:07
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6820
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6820
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1923:6669](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1924..6669
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..6820
                     /SMILES="CC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6820
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             complement(388..1197)
                     /ID="TARA_SAMEA6035815_MAG_00000013-scaffold_116_1"
                     /conf="100.00"
                     /cscore="83.46"
                     /gc_cont="0.665"
                     /gene="TARA_SAMEA6035815_MAG_00000013-scaffold_116_1"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="None"
                     /rbs_spacer="None"
                     /rscore="-4.58"
                     /score="84.75"
                     /score="84.7"
                     /source="Prodigal_v2.6.3"
                     /sscore="1.29"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MRLLSMLPFLAAMLGTGISDLRQDFQQTGSPQPAFGPPGSLWDND
                     VSNATTSVASQDGQSFARAADDFLLDDPNCSSGRFLVHRIRLHMVQNDSTPQSFAIEIY
                     NDDGTGQRPDSFAPIVTLTETSQTELGPFGPFTSLYEAEFVPAQPLALPGGRYWLAGLG
                     TVGGNNFLNFFAASNGALGQPANALVRVPQAGFSDWTPAEDALGPPSLHFAFAVDGGCQ
                     LSASAEEIPVLSGWSAMLLAAGLAAAAAWGLRDCGERTSGSSRGPTS"
                     /tscore="4.50"
                     /uscore="2.02"
     CDS             1924..6669
                     /ID="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (12-451). E-value:
                     4.9e-149. Score: 488.6. Matches aSDomain:
                     nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-scaffold_116_
                     2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (548-864). E-value: 2.4e-90.
                     Score: 294.7. Matches aSDomain:
                     nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-scaffold_116_
                     2_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1201-1396). E-value: 4.6e-55.
                     Score: 178.2. Matches aSDomain:
                     nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-scaffold_116_
                     2_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1491-1559). E-value: 2.7e-24.
                     Score: 77.0. Matches aSDomain:
                     nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-scaffold_116_
                     2_PCP.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /conf="99.99"
                     /cscore="633.55"
                     /gc_cont="0.663"
                     /gene="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 65.2; E-value:
                     7.6e-20)"
                     /gene_kind="biosynthetic"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.54"
                     /score="651.16"
                     /score="651.2"
                     /sec_met_domain="PP-binding (E-value: 1.6e-18, bitscore:
                     54.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.7e-92, bitscore: 294.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1e-155, bitscore: 505.8,
                     seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.9e-39, bitscore:
                     121.6, seeds: 230, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="17.62"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MSDTTGSFNGSEIAVVSMACRFPGASDLDAFWRNLRDGVESISFF
                     SDEELLQAGLSPEALADPRLVKAGGILDGIEDFDADFFGFLPSEAEVTDIQFRLFLECV
                     WEALEGGSVAPDSFSGLIGVFAGAGMNTYMLPYLPLDPQRADREGLLHARVFNGSDFLP
                     AQTCYRLDLRGPSVNVQSGCSTSLVAVHLACQSLLSGECDAALAGAATVIVPQVRGYLY
                     EEKMVHSPDGHCRAFDDQAAGTVGSNGAGAVLLQRLEDALEQGRPVLAVIKGSAINNDG
                     ALKAGFTSPSREGQAAVISEALAVAQVDPATISYVEAHGTGTEIGDVIEVEALSEAFQA
                     AGESARPGAEGEGTDRSSCALGSVKSNLGHLDTAAGVAGLIKTVLALRHRQIPPSLHFE
                     KPNPRIDFANGPFVVNDQLRPWTSQPGQPRRAGVSSFGMGGANAHVVLEEAPLAQAGHP
                     SSRWQLLTLSAKSEAALETATDRLAEHFRSRPDLNLADVAYTLQTGRKAFDFRRIAVCR
                     ESEEPARLLASRDPERIFEGRRQGPGRSLAFMFPGVGDQHPGMAAELYREEPGFRQPFE
                     ECCRLFEPLVGEDLAGVIHPQGAKPKATDQLDFRSMVSGRREDPSGASARLNQTLFAHT
                     SIFAVEYALARLWMSWGVIPDALIGHSVGEFAACCIAGVLPLSDAVRLVAERARLIQGL
                     EEGAMTAAPLPEDELGPLLGEALSIAAVNTPSMCVASGPVEAIADLERRLEERGHVSRR
                     VSSSHAFHSGMMLPVREPLQRLAASFDLRPPRIPCISSVTGTWLTEEQARDAEYWAQHS
                     CSTVRFADGVAQLMAAPGRILLETGPGRSLGGFALQHPDCSADQDLSVFSSLPHADDPV
                     PEAAFMLTTLGKLWSTGLPIDWQAFGQDEQRSDQRRCYATLPSYPFQRRRHWREPPRQA
                     AAEHLEPTVATSFQEAAVEPLRSPIEDCFYLPSWRRSVPPAAVDDGDSEGEAHWLLFMD
                     SQGLGREIVRQLQQRGAEVTTVSAGAGFVRSSRDEFRLDPDRKEDYTALLDELREQGRL
                     PQRVLHLWNVDGQPQEAGDGLGTECAQASYFRLLYLIQSLGELGFGSSLSLAAVSVGMW
                     AVSGEEKVQPEKALAVGPIRTLPSEAAGVRAACIDLQPDPLDGDWQGAAQRVLAEVQAG
                     LPQSVVAWRGRFRWVEEIVPARLEALGETDPLRSEGVYLIAGGLGGVGLAIAEAMARRK
                     RLRLALVSRRGLPPRARWESLLADQDPEFDPTPIRRVLALEQSGSEILIVSADISHPQQ
                     AKEAVDSVRLRFGGINGIVQAAGVPGVGLMQFKTRESAEAVLRPKVEGTLHLLEAVGEA
                     DLDFLAICSSLGSLFSEIGQSDYCAANSFLDALAQRRFLDGRRTVSIGWGLWRWDAWQH
                     AMSRFPKMRNRISDWRQRYGLTDEEGGEAFLRLLSCPMPQVIVSTYDPQPYTHGQGESL
                     LESLMDESGADDSRSRQGLSAEIAAPTNDYEQTILDIWKELFGFDEIGIQDHFMDLGGH
                     SILAIQLASRLREAFQVEIPMSTVFSMPTVAKLALVVEEALLDEIEQLTIDESEVLVEF
                     EE"
                     /tscore="4.50"
                     /uscore="0.58"
     aSDomain        1960..3276
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-s
                     caffold_116_2_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="4.90E-149"
                     /label="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2_PKS_K
                     S.1"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="451"
                     /protein_start="12"
                     /score="488.6"
                     /tool="antismash"
                     /translation="IAVVSMACRFPGASDLDAFWRNLRDGVESISFFSDEELLQAGLSP
                     EALADPRLVKAGGILDGIEDFDADFFGFLPSEAEVTDIQFRLFLECVWEALEGGSVAPD
                     SFSGLIGVFAGAGMNTYMLPYLPLDPQRADREGLLHARVFNGSDFLPAQTCYRLDLRGP
                     SVNVQSGCSTSLVAVHLACQSLLSGECDAALAGAATVIVPQVRGYLYEEKMVHSPDGHC
                     RAFDDQAAGTVGSNGAGAVLLQRLEDALEQGRPVLAVIKGSAINNDGALKAGFTSPSRE
                     GQAAVISEALAVAQVDPATISYVEAHGTGTEIGDVIEVEALSEAFQAAGESARPGAEGE
                     GTDRSSCALGSVKSNLGHLDTAAGVAGLIKTVLALRHRQIPPSLHFEKPNPRIDFANGP
                     FVVNDQLRPWTSQPGQPRRAGVSSFGMGGANAHVVLEEAP"
     aSModule        1960..6600
                     /complete
                     /domains="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_PKS_KS.1"
                     /domains="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_PKS_AT.1"
                     /domains="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_PKS_KR.1"
                     /domains="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_PCP.1"
                     /locus_tags="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2443..2490
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0001"
                     /evalue="3.90E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="189"
                     /protein_start="173"
                     /score="13.0"
                     /tool="antismash"
                     /translation="GPSVNVQSGCSTSLVA"
     CDS_motif       2866..2913
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0002"
                     /evalue="2.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="330"
                     /protein_start="314"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YVEAHGTGTEIGDVIE"
     CDS_motif       3007..3051
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0003"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="376"
                     /protein_start="361"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GSVKSNLGHLDTAAG"
     CDS_motif       3565..3618
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0004"
                     /evalue="2.20E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="565"
                     /protein_start="547"
                     /score="13.9"
                     /tool="antismash"
                     /translation="FMFPGVGDQHPGMAAELY"
     aSDomain        3568..4515
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-s
                     caffold_116_2_PKS_AT.1"
                     /evalue="2.40E-90"
                     /label="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2_PKS_A
                     T.1"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="864"
                     /protein_start="548"
                     /score="294.7"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFPGVGDQHPGMAAELYREEPGFRQPFEECCRLFEPLVGEDLAGV
                     IHPQGAKPKATDQLDFRSMVSGRREDPSGASARLNQTLFAHTSIFAVEYALARLWMSWG
                     VIPDALIGHSVGEFAACCIAGVLPLSDAVRLVAERARLIQGLEEGAMTAAPLPEDELGP
                     LLGEALSIAAVNTPSMCVASGPVEAIADLERRLEERGHVSRRVSSSHAFHSGMMLPVRE
                     PLQRLAASFDLRPPRIPCISSVTGTWLTEEQARDAEYWAQHSCSTVRFADGVAQLMAAP
                     GRILLETGPGRSLGGFALQHPDCSADQDLSVFSSL"
     CDS_motif       3877..3999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0005"
                     /evalue="1.60E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="692"
                     /protein_start="651"
                     /score="71.8"
                     /tool="antismash"
                     /translation="GVIPDALIGHSVGEFAACCIAGVLPLSDAVRLVAERARLIQ"
     CDS_motif       4081..4119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0006"
                     /evalue="3.00E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="732"
                     /protein_start="719"
                     /score="11.0"
                     /tool="antismash"
                     /translation="AAVNTPSMCVASG"
     CDS_motif       4342..4377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0007"
                     /evalue="7.60E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="818"
                     /protein_start="806"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YWAQHSCSTVRF"
     CDS_motif       4681..4701
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0008"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="926"
                     /protein_start="919"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="RRHWREP"
     aSDomain        5527..6111
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-s
                     caffold_116_2_PKS_KR.1"
                     /evalue="4.60E-55"
                     /label="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2_PKS_K
                     R.1"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="1396"
                     /protein_start="1201"
                     /score="178.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLIAGGLGGVGLAIAEAMARRKRLRLALVSRRGLPPRARWESL
                     LADQDPEFDPTPIRRVLALEQSGSEILIVSADISHPQQAKEAVDSVRLRFGGINGIVQA
                     AGVPGVGLMQFKTRESAEAVLRPKVEGTLHLLEAVGEADLDFLAICSSLGSLFSEIGQS
                     DYCAANSFLDALAQRRFLDGRRTVSIGWGLWR"
     CDS_motif       5530..5628
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0009"
                     /evalue="6.40E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="1235"
                     /protein_start="1202"
                     /score="34.8"
                     /tool="antismash"
                     /translation="VYLIAGGLGGVGLAIAEAMARRKRLRLALVSRR"
     CDS_motif       5956..6063
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_TARA_SAMEA6035815_MAG_00000013-sca
                     ffold_116_2_0010"
                     /evalue="2.80E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="1380"
                     /protein_start="1344"
                     /score="45.6"
                     /tool="antismash"
                     /translation="LDFLAICSSLGSLFSEIGQSDYCAANSFLDALAQRR"
     aSDomain        6397..6600
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_TARA_SAMEA6035815_MAG_00000013-s
                     caffold_116_2_PCP.1"
                     /evalue="2.70E-24"
                     /label="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2_PCP.1
                     "
                     /locus_tag="TARA_SAMEA6035815_MAG_00000013-scaffold_116_2"
                     /protein_end="1559"
                     /protein_start="1491"
                     /score="77.0"
                     /tool="antismash"
                     /translation="EQTILDIWKELFGFDEIGIQDHFMDLGGHSILAIQLASRLREAFQ
                     VEIPMSTVFSMPTVAKLALVVEE"
ORIGIN
        1 ctagggtttc gtcgaagcct cgcctgcggc tcgtttcgac tgcaccccag gctatctttg
       61 agagtcgccg ccccgttggg gctcaaggga aggggatccc tcctgtgccg aaacaactcc
      121 cccggggctc tggggaaggg atccctcctc gaccgaaact gctcccctct ggggctcagg
      181 ggaagcgatg acctcctgga ccgaaacagc tccctctcgg agccctgaaa gggcggccac
      241 tcccaaaacc agcccaggat gcagccggcg agcggcccgc gagccggcga aatcctgggt
      301 cgccgccttc ccttcccgta cagtcctgta aggacgctcc gttgggcgct tctacaggcg
      361 agcggtgcgt acgccggagg ccccgcgtca agaggtgggg ccccgagagc tgccgctggt
      421 cctttcgccg cagtcccgca atccccaagc cgccgctgct gccaggcccg ccgccaggag
      481 catcgcgctc cagccgctca agaccgggat ttcctcggca gacgccgaca gctggcagcc
      541 gccgtcgacg gcgaaggcga agtgaaggct gggcggaccg agggcgtcct cagccggcgt
      601 ccaatcggag aagccggctt gaggcacgcg gacgagggcg ttggccggct ggccgagggc
      661 gccgttggag gcggcgaaga agttcaggaa attgttgccg cccaccgttc ccaatcccgc
      721 cagccagtaa cggccgccgg gcaaggcaag gggctgggcg ggcacgaatt ccgcctcgta
      781 gagagatgtg aaagggccga aggggcccaa ctcggtctga gacgtctccg tcagggtgac
      841 gatgggagcg aagctgtcgg ggcgctgtcc cgtgccgtcg tcattgtaga tctcgatcgc
      901 gaagctctgg ggagtgctgt cgttctgcac catgtgcagg cgaatccggt gcacgaggaa
      961 tcgtccgctg gagcagttgg ggtcgtcgag caggaaatcg tcggctgccc gggcgaagga
     1021 ctgcccgtct tgcgaagcca cggacgtggt ggcattgctg acgtcgttgt cccagagcga
     1081 acccggcgga ccgaaggccg gctgcggcga acccgtctgc tggaagtcct gacgcagatc
     1141 ggagatgccc gttcccagca ttgctgctag aaacggcagc atcgaaagca aacgcatcgt
     1201 caccccactt gaactttgcc ctgtgaattc taaaagcaag ctctgtcgtg gtacagaagt
     1261 tgccgccgtt ctttttgctt tttcacataa caatgttttg tgcaatgttg ccttcccgcg
     1321 ggcctcggcc agacccgtct tcgacgcagc cagggactcc agcagccgtc ggccgcaagc
     1381 gggacaggat ccgacggtcc attggggccg tatcactgca gggagaaggg aatcggcaaa
     1441 acgtcgagcc tactcccgaa gggaatcgat ctgcggcgag tattgctgca ttcgctttcg
     1501 ctatgagaga ttgtgctgac ggcgcagcgt gatcgccctt caggcatcgc ggggcgagga
     1561 aggaaaccgt ggaggatcgc cgcggcttcg ggaacactca ggaggtttgg agccgcactt
     1621 cctcgaagtg gtggagaagg gcctcccttt cccttgtaac gcgagaccgc tgcaagccgc
     1681 cgagtgggcc aacccgcact ttcgaccgcc gatcgaggcg ccggcgatgg aggaaagccc
     1741 actcggcagg cgagagccga cagcgaacga ggatttgctg caaaatggtc ttcttcgaac
     1801 agtattccgg gctggactcc cactctggtc gggggctccc gagagcccgg ttgtcatcac
     1861 ccggagccaa gcggcaacga cgctctccgc aatacatcgg accatgattt caggagtgaa
     1921 gatatgagcg acacgaccgg ttccttcaac ggcagcgaga tcgccgtggt ttcgatggcc
     1981 tgccgtttcc ccggcgccag cgacctggac gccttttggc gaaatctgcg cgacggggtg
     2041 gaatcgatct cgttcttcag cgacgaagag ctgctgcaag ccggactgag cccggaagcc
     2101 ctggccgacc cgcgtttggt caaggcggga ggaatcctgg acggcatcga ggacttcgac
     2161 gctgatttct tcggcttcct gcccagcgaa gccgaggtaa ccgatatcca gttccgactc
     2221 tttctggaat gcgtttggga agctctggag ggcggttcgg tggcgcccga ctccttctcc
     2281 ggcctgatcg gggtcttcgc cggagccggc atgaacacct acatgctgcc ttacctccca
     2341 ttggatccgc agagggccga tcgggaaggg ctgctgcatg cccgggtctt caacggcagc
     2401 gactttctgc cggcgcagac ctgttatcga ctcgacctgc gggggcccag cgtcaacgtc
     2461 cagagcggat gctcaacctc gctggtggcg gtgcacctgg cctgccagag cttgctcagc
     2521 ggcgaatgcg atgccgcact ggccggcgcc gccacggtca tcgtccccca ggtgcggggg
     2581 tatctctacg aagagaagat ggtgcattcg cccgacgggc actgccgcgc attcgacgac
     2641 caagcggccg ggacggtggg aagcaacggc gccggcgccg tcttgctgca acgactggaa
     2701 gacgccttgg agcagggacg tcccgtgctg gcggtcatca aggggtcggc catcaacaac
     2761 gacggcgccc tcaaggccgg cttcacctcg cccagccgcg agggccaggc ggccgtcatc
     2821 tccgaagccc tggccgtggc tcaggtcgat cccgcgacca tcagctacgt cgaggcccat
     2881 ggaaccggaa ccgagatcgg ggacgtgatc gaggtcgaag ccctcagcga ggccttccag
     2941 gccgccggcg agagcgcaag gccaggcgcg gaaggtgaag gaaccgaccg atcgagctgc
     3001 gctctgggat cggtcaagag caacctgggg cacctcgaca ccgccgccgg cgtcgccggc
     3061 ctgatcaaga cggtcctggc cttgcgccat cgccagatcc cgcccagcct gcacttcgag
     3121 aagcccaacc cgcgcatcga ctttgccaac ggacctttcg tcgtcaacga ccagctgcgc
     3181 ccctggacgt cccagccggg ccagcctcgc agggcgggag tcagctcctt cggcatgggc
     3241 ggggccaacg cccacgtcgt cttggaggaa gcgccgcttg cccaggccgg acatccttcc
     3301 agccgctggc agcttctgac gctgtcggcc aagtccgaag ccgccttgga gacagccacg
     3361 gaccggttgg ccgagcactt tcgatcccgt cccgacctca acttggccga tgtcgcctac
     3421 acgcttcaga ccggccgcaa agccttcgat ttcagacgga ttgccgtctg ccgcgagtcc
     3481 gaagagccgg cccgattgct ggcttcgcgc gatcccgagc ggatcttcga gggccgccga
     3541 caaggccccg ggagaagcct ggccttcatg ttcccgggag tgggcgatca gcatccagga
     3601 atggctgcgg agctctaccg ggaagagccg ggcttccgcc agcctttcga ggagtgctgc
     3661 cgactcttcg agccgctggt gggagaggac ctggcaggcg tgatccatcc ccagggagcg
     3721 aagccgaagg cgacggacca actcgatttc cgcagcatgg tatcgggacg acgcgaggat
     3781 ccttcgggag cgtccgcccg cttgaatcag acgcttttcg cccacacctc catcttcgct
     3841 gtcgagtacg cactggcccg cttgtggatg tcttggggcg taattcccga tgcgctgatc
     3901 gggcacagcg tgggcgaatt cgcagcctgc tgcatcgcgg gcgtgctgcc gctgagcgac
     3961 gcggtgcgcc tggtcgccga gagggcgcgg ctgattcagg gactggaaga gggagcgatg
     4021 accgcggcgc ccctgcccga ggacgagctg gggccgctgt tgggggaggc gctctcgatc
     4081 gccgccgtca atacgccttc catgtgcgtc gcatcgggtc cggtcgaagc catcgccgac
     4141 ctggagcgca ggctcgagga acgagggcac gtgagccggc gcgtgtccag ctcccatgcc
     4201 tttcattcgg gcatgatgct gcccgtccgc gaaccgctcc agcgcctagc ggcctccttc
     4261 gatctgcgtc cgcctcggat cccttgcatc tcttccgtca cggggacttg gctgaccgag
     4321 gagcaagcca gggatgccga atattgggct cagcactcct gcagcaccgt ccgcttcgcc
     4381 gacggggtgg ctcagctgat ggccgctccc ggcaggatcc tgctggaaac cggccccgga
     4441 cgcagcctgg gcggattcgc tctgcagcac ccggattgca gcgccgatca ggatctttcc
     4501 gtcttctcct cgttgccgca tgcggacgac cctgtccccg aggccgcctt catgctcacg
     4561 accttgggga aactttggtc gacggggctg ccgatcgact ggcaagcctt cgggcaggac
     4621 gagcagcgat ccgaccagcg ccgctgctat gcgactctgc ccagctatcc cttccagcgc
     4681 cgccgccatt ggagagagcc tccccgccaa gctgcagccg agcatttgga gccaacggtt
     4741 gcaacgtctt tccaggaggc agccgtcgaa cctctgcgct cccccatcga ggattgcttc
     4801 tatctgcctt cctggcggcg aagcgtccct cccgccgccg tcgacgatgg cgacagcgag
     4861 ggcgaggcgc attggcttct cttcatggat tcgcagggcc tgggccggga gatcgtgcgc
     4921 cagctgcagc agcgcggcgc cgaggtcacc acggtctcgg cgggtgcggg attcgtccgc
     4981 tccagccggg acgaattcag gctggatccc gatcgcaagg aagactacac ggcattgctg
     5041 gacgagttgc gcgagcaagg acgactgccc cagcgcgtcc tgcatctgtg gaacgtggat
     5101 gggcagcccc aggaagccgg cgacgggttg gggaccgagt gcgcccaggc ctcctacttc
     5161 cggcttctct acctgatcca atccctgggc gaactgggct tcggctcctc gctgtcgctg
     5221 gctgcggttt cggtcggcat gtgggccgtg tcgggcgagg aaaaggtcca gccggaaaag
     5281 gctctcgcgg tgggaccgat tcggacgctc ccatccgagg ctgcaggcgt ccgcgccgct
     5341 tgcatcgact tgcagcccga tccgctcgat ggcgactggc agggggcggc ccaacgcgtc
     5401 ttggccgaag tgcaggccgg cctgcctcag agcgtagtgg cctggcgagg gcgcttccgc
     5461 tgggtggagg agatcgtgcc ggcgcgcttg gaggcgctgg gagagaccga tccgctgcgc
     5521 agcgagggcg tttacctcat tgcgggagga ctgggcggcg tgggactggc gatcgcagag
     5581 gccatggcgc ggcgcaagcg cctgcgcttg gccctggtga gccgtcgcgg acttccgccg
     5641 cgcgcccgat gggaatcgct gctggcggac caggacccgg aattcgatcc gacgcccatc
     5701 aggagggttc tggccctgga gcagtccggc tcggagattc tgatcgtctc ggccgacatc
     5761 agtcatcccc agcaggccaa ggaagccgtc gactcggtgc gccttcgatt cggagggatc
     5821 aacggcatcg tccaggccgc cggagtcccc ggggtgggcc tgatgcagtt caagacccgc
     5881 gagtcggctg aggccgtcct caggcccaag gttgagggca ctctccacct gcttgaggcg
     5941 gtgggcgaag ccgacctgga tttcctggcc atttgctctt cgctgggatc gctcttcagc
     6001 gagatcggcc agtccgacta ctgcgccgcc aactcattcc tggacgccct ggcccagcgg
     6061 cgattcctgg acggccgacg gacggtttcc atcggctggg gactgtggcg ctgggacgcc
     6121 tggcagcatg cgatgagtcg cttccccaag atgcgcaatc gcatctcgga ctggaggcag
     6181 cgctacggac tgaccgacga ggaaggcggc gaggcgttcc tgcgcttgct ctcctgcccc
     6241 atgccccagg tcatcgtcag cacctatgat ccccagccct atacgcacgg tcagggcgag
     6301 agcctgctgg aaagcctcat ggacgagtcc ggcgccgacg actcgcgcag ccgtcagggc
     6361 ttgagcgcgg agatcgctgc accgaccaac gactacgagc agaccattct ggacatctgg
     6421 aaggagctct tcggcttcga cgagatcggg atccaggatc acttcatgga cctgggaggc
     6481 cattccatcc tggccattca gctggcgtcg cgcctgcgcg aggcgttcca ggtggagatt
     6541 cccatgtcga ccgtgttctc gatgccgacc gtggccaaac tggcgctggt ggtggaagag
     6601 gcgcttctcg acgagatcga gcagctgacg atcgacgagt cggaagtgct tgtcgagttc
     6661 gaggagtagg agcggcgact ggcagggggc gtcccttgag gactcttcgg agaggacgcg
     6721 gcgacccagg actacgccgg ctcgctggcc gctcgccggc ttcatcctgg gctacgtttg
     6781 ggactggccg ccctttcagg gctctgggaa gacctcccag
//
