TARA_SAMEA6035815_MAG_00000013 - 50 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

TARA_SAMEA6035815_MAG_00000013-scaffold_1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,T1PKS	143,906	222,973

TARA_SAMEA6035815_MAG_00000013-scaffold_2

Region	Type	From	To
Region 2.1	lanthipeptide-class-i	86,520	112,815
Region 2.2	phosphonate	254,832	295,770
Region 2.3	NRPS	362,830	416,163

TARA_SAMEA6035815_MAG_00000013-scaffold_3

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	NRPS,T1PKS	47,579	172,918

TARA_SAMEA6035815_MAG_00000013-scaffold_5

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS,T1PKS	136,054	196,796
Region 5.2	NRPS,T1PKS	198,604	295,625

TARA_SAMEA6035815_MAG_00000013-scaffold_6

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	terpene	1	13,732
Region 6.2	NRPS,T1PKS	199,200	253,803

TARA_SAMEA6035815_MAG_00000013-scaffold_8

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	NRPS-like	48,986	93,335

TARA_SAMEA6035815_MAG_00000013-scaffold_10

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	T1PKS,NRPS-like	8,641	53,806

TARA_SAMEA6035815_MAG_00000013-scaffold_11

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	NRPS	34,481	81,200

TARA_SAMEA6035815_MAG_00000013-scaffold_12

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	NRPS	1	37,081

TARA_SAMEA6035815_MAG_00000013-scaffold_13

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	lassopeptide	7,081	29,468
Region 13.2	lanthipeptide-class-v	68,914	111,060

TARA_SAMEA6035815_MAG_00000013-scaffold_15

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	NRPS	1	35,615

TARA_SAMEA6035815_MAG_00000013-scaffold_16

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS-like,NRPS	31,375	117,972

TARA_SAMEA6035815_MAG_00000013-scaffold_17

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	T3PKS,RiPP-like	14,766	55,818

TARA_SAMEA6035815_MAG_00000013-scaffold_18

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	NRPS	2,732	46,844

TARA_SAMEA6035815_MAG_00000013-scaffold_19

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	NRPS	65,028	109,140

TARA_SAMEA6035815_MAG_00000013-scaffold_20

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	NRPS,T1PKS	13,046	103,838

TARA_SAMEA6035815_MAG_00000013-scaffold_21

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	NRPS	1	25,149

TARA_SAMEA6035815_MAG_00000013-scaffold_27

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	NRPS	1	27,682

TARA_SAMEA6035815_MAG_00000013-scaffold_28

Region	Type	From	To	Most similar known cluster		Similarity
Region 28.1	NRPS,T1PKS	1	39,551

TARA_SAMEA6035815_MAG_00000013-scaffold_29

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	NRPS	1	55,694

TARA_SAMEA6035815_MAG_00000013-scaffold_30

Region	Type	From	To	Most similar known cluster		Similarity
Region 30.1	T1PKS,NRPS	60,344	95,124

TARA_SAMEA6035815_MAG_00000013-scaffold_33

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	T1PKS,ladderane	29,768	88,913

TARA_SAMEA6035815_MAG_00000013-scaffold_36

Region	Type	From	To	Most similar known cluster		Similarity
Region 36.1	NRPS-like	3,675	46,392

TARA_SAMEA6035815_MAG_00000013-scaffold_37

Region	Type	From	To	Most similar known cluster		Similarity
Region 37.1	NRPS	1	42,257

TARA_SAMEA6035815_MAG_00000013-scaffold_38

Region	Type	From	To	Most similar known cluster		Similarity
Region 38.1	NRPS,RiPP-like	1	47,146

TARA_SAMEA6035815_MAG_00000013-scaffold_39

Region	Type	From	To	Most similar known cluster		Similarity
Region 39.1	RiPP-like	70,289	81,308

TARA_SAMEA6035815_MAG_00000013-scaffold_47

Region	Type	From	To	Most similar known cluster		Similarity
Region 47.1	NRPS	3,401	59,180

TARA_SAMEA6035815_MAG_00000013-scaffold_49

Region	Type	From	To	Most similar known cluster		Similarity
Region 49.1	NRPS-like	1	33,149

TARA_SAMEA6035815_MAG_00000013-scaffold_50

Region	Type	From	To	Most similar known cluster		Similarity
Region 50.1	NRPS	1	28,079

TARA_SAMEA6035815_MAG_00000013-scaffold_51

Region	Type	From	To	Most similar known cluster		Similarity
Region 51.1	NRPS,T1PKS	1	61,928

TARA_SAMEA6035815_MAG_00000013-scaffold_54

Region	Type	From	To	Most similar known cluster		Similarity
Region 54.1	RiPP-like	51,586	58,582

TARA_SAMEA6035815_MAG_00000013-scaffold_55

Region	Type	From	To	Most similar known cluster		Similarity
Region 55.1	NRPS-like	1	21,451

TARA_SAMEA6035815_MAG_00000013-scaffold_61

Region	Type	From	To	Most similar known cluster		Similarity
Region 61.1	terpene	14,507	36,495

TARA_SAMEA6035815_MAG_00000013-scaffold_63

Region	Type	From	To	Most similar known cluster		Similarity
Region 63.1	cyanobactin	1	13,674

TARA_SAMEA6035815_MAG_00000013-scaffold_65

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	NRPS-like,RiPP-like	24,586	47,152

TARA_SAMEA6035815_MAG_00000013-scaffold_66

Region	Type	From	To	Most similar known cluster		Similarity
Region 66.1	NRPS-like,T1PKS	7,440	46,946

TARA_SAMEA6035815_MAG_00000013-scaffold_68

Region	Type	From	To	Most similar known cluster		Similarity
Region 68.1	lanthipeptide-class-iv	1	18,995

TARA_SAMEA6035815_MAG_00000013-scaffold_69

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	cyanobactin	3,432	26,191

TARA_SAMEA6035815_MAG_00000013-scaffold_76

Region	Type	From	To	Most similar known cluster		Similarity
Region 76.1	RiPP-like	8,048	19,955

TARA_SAMEA6035815_MAG_00000013-scaffold_77

Region	Type	From	To	Most similar known cluster		Similarity
Region 77.1	NRPS,RiPP-like	1	31,448

TARA_SAMEA6035815_MAG_00000013-scaffold_80

Region	Type	From	To	Most similar known cluster		Similarity
Region 80.1	NRPS	1	23,839

TARA_SAMEA6035815_MAG_00000013-scaffold_87

Region	Type	From	To	Most similar known cluster		Similarity
Region 87.1	T1PKS,NRPS	1	27,147

TARA_SAMEA6035815_MAG_00000013-scaffold_88

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	NRPS	1	25,162

TARA_SAMEA6035815_MAG_00000013-scaffold_93

Region	Type	From	To	Most similar known cluster		Similarity
Region 93.1	NRPS	1	19,988

TARA_SAMEA6035815_MAG_00000013-scaffold_116

Region	Type	From	To	Most similar known cluster		Similarity
Region 116.1	T1PKS	1	6,820

Region	Type	From	To	Similarity
Region 1.1	NRPS,T1PKS	143,906	222,973
Region 2.1	lanthipeptide-class-i	86,520	112,815
Region 2.2	phosphonate	254,832	295,770
Region 2.3	NRPS	362,830	416,163
Region 3.1	NRPS,T1PKS	47,579	172,918
Region 5.1	NRPS,T1PKS	136,054	196,796
Region 5.2	NRPS,T1PKS	198,604	295,625
Region 6.1	terpene	1	13,732
Region 6.2	NRPS,T1PKS	199,200	253,803
Region 8.1	NRPS-like	48,986	93,335
Region 10.1	T1PKS,NRPS-like	8,641	53,806
Region 11.1	NRPS	34,481	81,200
Region 12.1	NRPS	1	37,081
Region 13.1	lassopeptide	7,081	29,468
Region 13.2	lanthipeptide-class-v	68,914	111,060
Region 15.1	NRPS	1	35,615
Region 16.1	NRPS-like,NRPS	31,375	117,972
Region 17.1	T3PKS,RiPP-like	14,766	55,818
Region 18.1	NRPS	2,732	46,844
Region 19.1	NRPS	65,028	109,140
Region 20.1	NRPS,T1PKS	13,046	103,838
Region 21.1	NRPS	1	25,149
Region 27.1	NRPS	1	27,682
Region 28.1	NRPS,T1PKS	1	39,551
Region 29.1	NRPS	1	55,694
Region 30.1	T1PKS,NRPS	60,344	95,124
Region 33.1	T1PKS,ladderane	29,768	88,913
Region 36.1	NRPS-like	3,675	46,392
Region 37.1	NRPS	1	42,257
Region 38.1	NRPS,RiPP-like	1	47,146
Region 39.1	RiPP-like	70,289	81,308
Region 47.1	NRPS	3,401	59,180
Region 49.1	NRPS-like	1	33,149
Region 50.1	NRPS	1	28,079
Region 51.1	NRPS,T1PKS	1	61,928
Region 54.1	RiPP-like	51,586	58,582
Region 55.1	NRPS-like	1	21,451
Region 61.1	terpene	14,507	36,495
Region 63.1	cyanobactin	1	13,674
Region 65.1	NRPS-like,RiPP-like	24,586	47,152
Region 66.1	NRPS-like,T1PKS	7,440	46,946
Region 68.1	lanthipeptide-class-iv	1	18,995
Region 69.1	cyanobactin	3,432	26,191
Region 76.1	RiPP-like	8,048	19,955
Region 77.1	NRPS,RiPP-like	1	31,448
Region 80.1	NRPS	1	23,839
Region 87.1	T1PKS,NRPS	1	27,147
Region 88.1	NRPS	1	25,162
Region 93.1	NRPS	1	19,988
Region 116.1	T1PKS	1	6,820

No secondary metabolite regions were found in these records:: TARA_SAMEA6035815_MAG_00000013-scaffold_4; TARA_SAMEA6035815_MAG_00000013-scaffold_7; TARA_SAMEA6035815_MAG_00000013-scaffold_9; TARA_SAMEA6035815_MAG_00000013-scaffold_14; TARA_SAMEA6035815_MAG_00000013-scaffold_22; TARA_SAMEA6035815_MAG_00000013-scaffold_23; TARA_SAMEA6035815_MAG_00000013-scaffold_24; TARA_SAMEA6035815_MAG_00000013-scaffold_25; TARA_SAMEA6035815_MAG_00000013-scaffold_26; TARA_SAMEA6035815_MAG_00000013-scaffold_31; TARA_SAMEA6035815_MAG_00000013-scaffold_32; TARA_SAMEA6035815_MAG_00000013-scaffold_34; TARA_SAMEA6035815_MAG_00000013-scaffold_35; TARA_SAMEA6035815_MAG_00000013-scaffold_40; TARA_SAMEA6035815_MAG_00000013-scaffold_41; TARA_SAMEA6035815_MAG_00000013-scaffold_42; TARA_SAMEA6035815_MAG_00000013-scaffold_43; TARA_SAMEA6035815_MAG_00000013-scaffold_44; TARA_SAMEA6035815_MAG_00000013-scaffold_45; TARA_SAMEA6035815_MAG_00000013-scaffold_46; TARA_SAMEA6035815_MAG_00000013-scaffold_48; TARA_SAMEA6035815_MAG_00000013-scaffold_52; TARA_SAMEA6035815_MAG_00000013-scaffold_53; TARA_SAMEA6035815_MAG_00000013-scaffold_56; TARA_SAMEA6035815_MAG_00000013-scaffold_57; TARA_SAMEA6035815_MAG_00000013-scaffold_58; TARA_SAMEA6035815_MAG_00000013-scaffold_59; TARA_SAMEA6035815_MAG_00000013-scaffold_60; TARA_SAMEA6035815_MAG_00000013-scaffold_62; TARA_SAMEA6035815_MAG_00000013-scaffold_64; TARA_SAMEA6035815_MAG_00000013-scaffold_67; TARA_SAMEA6035815_MAG_00000013-scaffold_70; TARA_SAMEA6035815_MAG_00000013-scaffold_71; TARA_SAMEA6035815_MAG_00000013-scaffold_72; TARA_SAMEA6035815_MAG_00000013-scaffold_73; TARA_SAMEA6035815_MAG_00000013-scaffold_74; TARA_SAMEA6035815_MAG_00000013-scaffold_75; TARA_SAMEA6035815_MAG_00000013-scaffold_78; TARA_SAMEA6035815_MAG_00000013-scaffold_79; TARA_SAMEA6035815_MAG_00000013-scaffold_81; TARA_SAMEA6035815_MAG_00000013-scaffold_82; TARA_SAMEA6035815_MAG_00000013-scaffold_83; TARA_SAMEA6035815_MAG_00000013-scaffold_84; TARA_SAMEA6035815_MAG_00000013-scaffold_85; TARA_SAMEA6035815_MAG_00000013-scaffold_86; TARA_SAMEA6035815_MAG_00000013-scaffold_89; TARA_SAMEA6035815_MAG_00000013-scaffold_90; TARA_SAMEA6035815_MAG_00000013-scaffold_91; TARA_SAMEA6035815_MAG_00000013-scaffold_92; TARA_SAMEA6035815_MAG_00000013-scaffold_94; TARA_SAMEA6035815_MAG_00000013-scaffold_95; TARA_SAMEA6035815_MAG_00000013-scaffold_96; TARA_SAMEA6035815_MAG_00000013-scaffold_97; TARA_SAMEA6035815_MAG_00000013-scaffold_98; TARA_SAMEA6035815_MAG_00000013-scaffold_99; TARA_SAMEA6035815_MAG_00000013-scaffold_100; TARA_SAMEA6035815_MAG_00000013-scaffold_101; TARA_SAMEA6035815_MAG_00000013-scaffold_102; TARA_SAMEA6035815_MAG_00000013-scaffold_103; TARA_SAMEA6035815_MAG_00000013-scaffold_104; TARA_SAMEA6035815_MAG_00000013-scaffold_105; TARA_SAMEA6035815_MAG_00000013-scaffold_106; TARA_SAMEA6035815_MAG_00000013-scaffold_107; TARA_SAMEA6035815_MAG_00000013-scaffold_108; TARA_SAMEA6035815_MAG_00000013-scaffold_109; TARA_SAMEA6035815_MAG_00000013-scaffold_110; TARA_SAMEA6035815_MAG_00000013-scaffold_111; TARA_SAMEA6035815_MAG_00000013-scaffold_112; TARA_SAMEA6035815_MAG_00000013-scaffold_113; TARA_SAMEA6035815_MAG_00000013-scaffold_114; TARA_SAMEA6035815_MAG_00000013-scaffold_115; TARA_SAMEA6035815_MAG_00000013-scaffold_117; TARA_SAMEA6035815_MAG_00000013-scaffold_118; TARA_SAMEA6035815_MAG_00000013-scaffold_119; TARA_SAMEA6035815_MAG_00000013-scaffold_120; TARA_SAMEA6035815_MAG_00000013-scaffold_121; TARA_SAMEA6035815_MAG_00000013-scaffold_122

Compact view

TARA_SAMEA6035815_MAG_00000013-scaffold_1 - Region 1 - NRPS,T1PKS

Download region GenBank file

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Location: 143,906 - 222,973 nt. (total: 79,068 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 143905 - 222973:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - X) + (mal - NMe-X - X) + (ohmal - leu - pro - mal - val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_1_120

Search NORINE for peptide: strict or relaxed

PKS_AT (538..837): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 100.5
Methoxymalonyl-CoA: 69.7
Methylmalonyl-CoA: 69.0
Isobutyryl-CoA: 48.8
inactive: 39.4
Propionyl-CoA: 38.2
Benzoyl-CoA: 34.9
Ethylmalonyl-CoA: 31.5
2-Methylbutyryl-CoA: 31.2
CHC-CoA: 27.3
fatty_acid: 24.3
Acetyl-CoA: 23.3
3-Methylbutyryl-CoA: 16.1
trans-1,2-CPDA: 14.2

AMP-binding (2014..2408): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAwFFGLVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 80% (moderate)

AMP-binding (3091..3496): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvAqVaK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 70% (weak)

PKS_AT (4234..4517): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; inactive: 54.2%; Ethylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 117.0
inactive: 74.4
Methoxymalonyl-CoA: 47.8
Methylmalonyl-CoA: 39.8
Propionyl-CoA: 27.7
Benzoyl-CoA: 16.3
Ethylmalonyl-CoA: 15.6
Isobutyryl-CoA: 14.1
2-Methylbutyryl-CoA: 12.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

AMP-binding (5191..5590): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALWaGGiFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 80% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_1_121

Search NORINE for peptide: strict or relaxed

PKS_AT (531..834): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 151.1
inactive: 84.9
Methylmalonyl-CoA: 51.2
Methoxymalonyl-CoA: 47.6
Propionyl-CoA: 33.5
Ethylmalonyl-CoA: 22.5
fatty_acid: 17.4
2-Methylbutyryl-CoA: 14.8
Benzoyl-CoA: 14.5
Isobutyryl-CoA: 12.4
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

AMP-binding (1495..1889): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAaFwGLVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

AMP-binding (2967..3364): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAgDyGfiDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_1_122

Search NORINE for peptide: strict or relaxed

AMP-binding (620..1022): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DALWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

AMP-binding (1721..2122): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAfLIGAtiK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_2 - Region 1 - lanthipeptide-class-i

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Location: 86,520 - 112,815 nt. (total: 26,296 nt) Show pHMM detection rules used

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Lanthipeptides

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

TARA_SAMEA6035815_MAG_00000013-scaffold_2 - Region 2 - phosphonate

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Location: 254,832 - 295,770 nt. (total: 40,939 nt) Show pHMM detection rules used

phosphonate: phosphonates

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

TARA_SAMEA6035815_MAG_00000013-scaffold_2 - Region 3 - NRPS

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Location: 362,830 - 416,163 nt. (total: 53,334 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 362829 - 416163:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly) + (NMe-gln - NMe-gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_2_304

Search NORINE for peptide: strict or relaxed

AMP-binding (541..941): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DptQFGLIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 80% (moderate)

AMP-binding (2047..2445): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_2_305

Search NORINE for peptide: strict or relaxed

AMP-binding (521..913): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_3 - Region 1 - NRPS,T1PKS

Download region GenBank file

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Location: 47,579 - 172,918 nt. (total: 125,340 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 47578 - 172918:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gln) + (ser - X) + (asn - val) + (X) + (D-thr) + (asn - pro) + (gly - D-asn - D-NMe-X - D-asn - val) + (ohmal) + (X - leu - X - gln - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_3_44

Search NORINE for peptide: strict or relaxed

AMP-binding (51..454): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DiWQFGvIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 80% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_45

Search NORINE for peptide: strict or relaxed

CAL_domain (72..522): pk

minowa: AHBA

Prediction, score:

AHBA: 13.7
NH2: 10.4
shikimic_acid: 10.3
fatty_acid: 9.7
Acetyl-CoA: 2.4

AMP-binding (1200..1599): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHVSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (2264..2671): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAeDIGtVvK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_47

Search NORINE for peptide: strict or relaxed

AMP-binding (460..860): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1537..1939): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_49

Search NORINE for peptide: strict or relaxed

AMP-binding (503..904): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_50

Search NORINE for peptide: strict or relaxed

AMP-binding (505..911): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNVGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_52

Search NORINE for peptide: strict or relaxed

AMP-binding (468..869): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DFTKvGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

AMP-binding (1537..1940): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFlAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_54

Search NORINE for peptide: strict or relaxed

AMP-binding (495..887): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1538..1924): asn

NRPSPredictor2: asn

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (3034..3432): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVtnIAlIYK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 70% (weak)

AMP-binding (4987..5373): asn

NRPSPredictor2: asn

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (6477..6871): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_3_55

PKS_AT (540..838): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 70.8%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 151.5
inactive: 86.2
Methoxymalonyl-CoA: 73.5
Methylmalonyl-CoA: 59.8
Propionyl-CoA: 50.4
Ethylmalonyl-CoA: 35.6
2-Methylbutyryl-CoA: 32.2
Isobutyryl-CoA: 30.4
Acetyl-CoA: 25.6
trans-1,2-CPDA: 19.5
CHC-CoA: 18.6
Benzoyl-CoA: 15.0
3-Methylbutyryl-CoA: 12.9
fatty_acid: 10.7

TARA_SAMEA6035815_MAG_00000013-scaffold_3_57

Search NORINE for peptide: strict or relaxed

AMP-binding (470..869): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvgNLGLIdK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 70% (weak)

AMP-binding (1503..1894): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGlVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 90% (moderate)

AMP-binding (2531..2924): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DarNiGsINK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 60% (weak)

AMP-binding (3564..3961): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAaDIGgiDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

AMP-binding (4596..4981): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_5 - Region 1 - NRPS,T1PKS

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Location: 136,054 - 196,796 nt. (total: 60,743 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 136053 - 196796:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - leu - leu - mal - ile - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_5_119

Search NORINE for peptide: strict or relaxed

AMP-binding (455..854): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DpLVvGAVvK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 70% (weak)

AMP-binding (1534..1930): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGhVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 90% (moderate)

AMP-binding (2603..3016): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGhVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 90% (moderate)

PKS_AT (3754..4059): mal

ATSignature: Methylmalonyl-CoA, Methoxymalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 58.3%; Methoxymalonyl-CoA: 58.3%; Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 110.0
Methoxymalonyl-CoA: 87.6
Methylmalonyl-CoA: 81.5
Ethylmalonyl-CoA: 60.8
Propionyl-CoA: 60.1
inactive: 54.1
Acetyl-CoA: 34.1
2-Methylbutyryl-CoA: 30.3
trans-1,2-CPDA: 29.9
Isobutyryl-CoA: 26.5
CHC-CoA: 26.1
Benzoyl-CoA: 22.6
3-Methylbutyryl-CoA: 12.5
fatty_acid: 11.1

AMP-binding (4744..5158): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVvFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

PKS_AT (6469..6767): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Methylmalonyl-CoA: 58.3%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 127.9
Methylmalonyl-CoA: 73.2
Methoxymalonyl-CoA: 64.5
inactive: 46.9
Propionyl-CoA: 45.7
Isobutyryl-CoA: 42.3
Ethylmalonyl-CoA: 32.3
2-Methylbutyryl-CoA: 27.3
Benzoyl-CoA: 21.9
CHC-CoA: 19.7
Acetyl-CoA: 15.3
fatty_acid: 13.8
trans-1,2-CPDA: 10.3
3-Methylbutyryl-CoA: 0.0

TARA_SAMEA6035815_MAG_00000013-scaffold_5 - Region 2 - NRPS,T1PKS

Download region GenBank file

Download region SVG

Location: 198,604 - 295,625 nt. (total: 97,022 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 198603 - 295625:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser - D-ser) + (asn - X) + (X - ser) + (X - gly) + (val - X - X) + (glu - X - X) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 198603 - 290921:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser - D-ser) + (asn - X) + (X - ser) + (X - gly) + (val - X - X) + (glu - X - X) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 250924 - 295625:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - gly) + (val - X - X) + (glu - X - X) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_5_152

Search NORINE for peptide: strict or relaxed

CAL_domain (42..488): pk

minowa: NH2

Prediction, score:

NH2: 186.1
fatty_acid: 40.5
AHBA: 8.9
shikimic_acid: 0.0
Acetyl-CoA: -0.2

AMP-binding (1168..1571): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHVSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (2275..2674): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_5_154

Search NORINE for peptide: strict or relaxed

AMP-binding (459..866): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1539..1942): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvENiGcItK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_5_156

Search NORINE for peptide: strict or relaxed

AMP-binding (506..910): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DaEdiGTiVK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 60% (weak)

AMP-binding (1577..1976): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHiSLIEK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_5_157

Search NORINE for peptide: strict or relaxed

AMP-binding (502..906): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DTEdiGTiVK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 70% (weak)

AMP-binding (1581..1989): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_5_158

Search NORINE for peptide: strict or relaxed

AMP-binding (480..877): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (1547..1947): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

AMP-binding (2603..3011): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVeDVGvIiK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_5_159

Search NORINE for peptide: strict or relaxed

AMP-binding (501..906): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DTEdiGTiVK
Nearest Stachelhaus code:: lys-b
Stachelhaus code match:: 70% (weak)

AMP-binding (1584..1983): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

AMP-binding (2645..3054): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVenVGAIDK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 80% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_5_160

PKS_AT (529..824): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 98.8
Methoxymalonyl-CoA: 65.8
Methylmalonyl-CoA: 58.2
inactive: 51.2
Ethylmalonyl-CoA: 50.7
Propionyl-CoA: 30.1
Benzoyl-CoA: 21.5
2-Methylbutyryl-CoA: 16.9
trans-1,2-CPDA: 16.2
Isobutyryl-CoA: 12.6
CHC-CoA: 11.8
3-Methylbutyryl-CoA: 4.7
fatty_acid: 0.0
Acetyl-CoA: 0.0

TARA_SAMEA6035815_MAG_00000013-scaffold_6 - Region 1 - terpene

Download region GenBank file

Download region SVG

Location: 1 - 13,732 nt. (total: 13,732 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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TARA_SAMEA6035815_MAG_00000013-scaffold_6 - Region 2 - NRPS,T1PKS

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Location: 199,200 - 253,803 nt. (total: 54,604 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 199199 - 253803:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_6_158

Search NORINE for peptide: strict or relaxed

AMP-binding (529..977): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFfIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (1657..2048): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGgTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (2766..3210): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLedVGsIGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 70% (weak)

PKS_AT (3966..4247): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 12.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

TARA_SAMEA6035815_MAG_00000013-scaffold_8 - Region 1 - NRPS-like

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Location: 48,986 - 93,335 nt. (total: 44,350 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 48985 - 93335:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_8_65

Search NORINE for peptide: strict or relaxed

AMP-binding (556..1003): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aLclvGGPvK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_10 - Region 1 - NRPS-like,T1PKS

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Location: 8,641 - 53,806 nt. (total: 45,166 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

Selected features only

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TARA_SAMEA6035815_MAG_00000013-scaffold_11 - Region 1 - NRPS

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Location: 34,481 - 81,200 nt. (total: 46,720 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 34480 - 81200:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_11_46

Search NORINE for peptide: strict or relaxed

AMP-binding (1362..1768): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DArAlAqliK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_12 - Region 1 - NRPS

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Location: 1 - 37,081 nt. (total: 37,081 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 37081:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_12_13

Search NORINE for peptide: strict or relaxed

AMP-binding (32..436): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPgQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_12_16

Search NORINE for peptide: strict or relaxed

AMP-binding (456..848): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_13 - Region 1 - lassopeptide

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Location: 7,081 - 29,468 nt. (total: 22,388 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

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Lasso peptides

Lasso peptide predictions

Lassopeptides - No core peptides found.

Lasso peptides

Core peptide predictions

No core peptides found.

TARA_SAMEA6035815_MAG_00000013-scaffold_13 - Region 2 - lanthipeptide-class-v

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Location: 68,914 - 111,060 nt. (total: 42,147 nt) Show pHMM detection rules used

lanthipeptide-class-v: (APH and HopA1)

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Lanthipeptides

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

TARA_SAMEA6035815_MAG_00000013-scaffold_15 - Region 1 - NRPS

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Location: 1 - 35,615 nt. (total: 35,615 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 35615:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - thr - pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_15_7

Search NORINE for peptide: strict or relaxed

AMP-binding (545..944): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DgFfIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 80% (moderate)

AMP-binding (1640..2065): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (2749..3170): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_16 - Region 1 - NRPS,NRPS-like

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Location: 31,375 - 117,972 nt. (total: 86,598 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 31374 - 117972:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (thr - X) + (asn - X) + (X) + (D-asn) + (thr - pro) + (asp - gly)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 31374 - 69052:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (thr - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 33590 - 117972:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (thr - X) + (asn - X) + (X) + (D-asn) + (thr - pro) + (asp - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_16_40

Search NORINE for peptide: strict or relaxed

AMP-binding (27..438): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFEdTgtiiK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_16_41

Search NORINE for peptide: strict or relaxed

CAL_domain (154..464): pk

minowa: NH2

Prediction, score:

NH2: 138.1
Acetyl-CoA: 35.4
fatty_acid: 22.7
shikimic_acid: 0.0
AHBA: 0.0

AMP-binding (1156..1566): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (2231..2640): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLedIGtVvK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_16_47

Search NORINE for peptide: strict or relaxed

AMP-binding (45..447): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1124..1525): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSaLiAEVwK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_16_49

Search NORINE for peptide: strict or relaxed

AMP-binding (529..945): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvENiGaItK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_16_51

Search NORINE for peptide: strict or relaxed

AMP-binding (459..863): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DFTKvGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_16_53

Search NORINE for peptide: strict or relaxed

AMP-binding (130..536): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWSVGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (1210..1607): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_16_55

Search NORINE for peptide: strict or relaxed

AMP-binding (17..418): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DtKDLGlVDK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 80% (moderate)

AMP-binding (1094..1487): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGVIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_17 - Region 1 - RiPP-like,T3PKS

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Location: 14,766 - 55,818 nt. (total: 41,053 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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TARA_SAMEA6035815_MAG_00000013-scaffold_18 - Region 1 - NRPS

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Location: 2,732 - 46,844 nt. (total: 44,113 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 2731 - 46844:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_18_23

Search NORINE for peptide: strict or relaxed

AMP-binding (518..902): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: esWFLrfgVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_19 - Region 1 - NRPS

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Location: 65,028 - 109,140 nt. (total: 44,113 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 65027 - 109140:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_19_64

Search NORINE for peptide: strict or relaxed

AMP-binding (518..902): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: esWFLrfgVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_20 - Region 1 - NRPS,T1PKS

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Location: 13,046 - 103,838 nt. (total: 90,793 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13045 - 103838:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - D-X - X - X) + (ohmal) + (gln) + (ohmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_20_31

Search NORINE for peptide: strict or relaxed

CAL_domain (50..492): pk

minowa: NH2

Prediction, score:

NH2: 29.4
fatty_acid: 12.2
AHBA: 11.8
Acetyl-CoA: -1.1
shikimic_acid: -2.0

AMP-binding (1177..1577): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (2254..2659): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvEnagAVtK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 50% (weak)

AMP-binding (3795..4198): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAdicK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 70% (weak)

AMP-binding (4865..5268): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DqEnIGaVtK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 60% (weak)

AMP-binding (5930..6328): X

NRPSPredictor2: phe, trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: eAWlLqlVaK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

AMP-binding (7133..7533): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_20_32

PKS_AT (535..840): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 66.7%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 125.6
Methoxymalonyl-CoA: 63.9
inactive: 63.1
Methylmalonyl-CoA: 49.5
Propionyl-CoA: 44.4
2-Methylbutyryl-CoA: 27.1
Isobutyryl-CoA: 17.8
CHC-CoA: 15.6
Ethylmalonyl-CoA: 15.0
3-Methylbutyryl-CoA: 13.7
Benzoyl-CoA: 11.9
Acetyl-CoA: 11.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0

TARA_SAMEA6035815_MAG_00000013-scaffold_20_35

Search NORINE for peptide: strict or relaxed

AMP-binding (266..677): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGiVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_20_36

PKS_AT (2031..2328): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 187.0
inactive: 95.4
Methoxymalonyl-CoA: 71.2
Methylmalonyl-CoA: 62.6
Propionyl-CoA: 39.4
Isobutyryl-CoA: 36.3
Ethylmalonyl-CoA: 30.2
Acetyl-CoA: 23.6
Benzoyl-CoA: 20.4
fatty_acid: 18.3
CHC-CoA: 16.7
2-Methylbutyryl-CoA: 16.5
3-Methylbutyryl-CoA: 8.8
trans-1,2-CPDA: 7.3

TARA_SAMEA6035815_MAG_00000013-scaffold_20_37

PKS_AT (546..842): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 83.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 148.4
inactive: 85.8
Methoxymalonyl-CoA: 47.4
Methylmalonyl-CoA: 37.3
Propionyl-CoA: 32.0
CHC-CoA: 17.3
2-Methylbutyryl-CoA: 17.3
Ethylmalonyl-CoA: 16.2
Benzoyl-CoA: 12.8
Acetyl-CoA: 9.1
Isobutyryl-CoA: 8.5
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

TARA_SAMEA6035815_MAG_00000013-scaffold_21 - Region 1 - NRPS

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Location: 1 - 25,149 nt. (total: 25,149 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 25149:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_21_2

Search NORINE for peptide: strict or relaxed

AMP-binding (782..1180): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFlLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_27 - Region 1 - NRPS

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Location: 1 - 27,682 nt. (total: 27,682 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27682:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_27_1

Search NORINE for peptide: strict or relaxed

AMP-binding (590..986): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAlDLGVVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 90% (moderate)

AMP-binding (1634..2029): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: glu, gln
Single AA prediction:: glu

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDfGVVnK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 80% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_28 - Region 1 - NRPS,T1PKS

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Location: 1 - 39,551 nt. (total: 39,551 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 39551:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ile - X - thr - X) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_28_2

PKS_AT (520..801): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 66.7%; Propionyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 137.0
inactive: 89.5
Methoxymalonyl-CoA: 77.4
Methylmalonyl-CoA: 59.8
Ethylmalonyl-CoA: 40.1
Isobutyryl-CoA: 36.6
Propionyl-CoA: 31.2
CHC-CoA: 25.7
trans-1,2-CPDA: 21.0
Acetyl-CoA: 20.0
2-Methylbutyryl-CoA: 19.3
Benzoyl-CoA: 18.6
3-Methylbutyryl-CoA: 13.5
fatty_acid: 10.5

TARA_SAMEA6035815_MAG_00000013-scaffold_28_3

Search NORINE for peptide: strict or relaxed

AMP-binding (559..962): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

AMP-binding (1658..2060): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAehLGAItK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 70% (weak)

AMP-binding (2735..3149): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWSfGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 90% (moderate)

AMP-binding (3824..4251): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DisFaGaVlK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_29 - Region 1 - NRPS

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Location: 1 - 55,694 nt. (total: 55,694 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 55694:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-ile - D-X - gly - val) + (asp - leu - D-NMe-phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_29_7

Search NORINE for peptide: strict or relaxed

AMP-binding (552..950): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGaTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (2064..2478): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeItAdDK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 60% (weak)

AMP-binding (3597..4005): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DImQiGgIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 70% (weak)

AMP-binding (4662..5061): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_29_9

Search NORINE for peptide: strict or relaxed

AMP-binding (457..863): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (1526..1921): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

AMP-binding (2585..2974): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTVAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_30 - Region 1 - NRPS,T1PKS

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Location: 60,344 - 95,124 nt. (total: 34,781 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 60343 - 95124:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_30_54

Search NORINE for peptide: strict or relaxed

AMP-binding (527..931): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAFfVgAViK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 70% (weak)

AMP-binding (1659..2049): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGgTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (2732..3135): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVenVGAIgK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 70% (weak)

PKS_AT (3879..4170): mal

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 58.3%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 102.6
Methoxymalonyl-CoA: 60.6
Methylmalonyl-CoA: 55.2
inactive: 52.8
Isobutyryl-CoA: 31.7
Propionyl-CoA: 25.4
fatty_acid: 17.6
Ethylmalonyl-CoA: 17.4
Benzoyl-CoA: 15.1
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

TARA_SAMEA6035815_MAG_00000013-scaffold_33 - Region 1 - T1PKS,ladderane

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Location: 29,768 - 88,913 nt. (total: 59,146 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
ladderane: ladderane

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TARA_SAMEA6035815_MAG_00000013-scaffold_36 - Region 1 - NRPS-like

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Location: 3,675 - 46,392 nt. (total: 42,718 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 3674 - 46392:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_36_25

Search NORINE for peptide: strict or relaxed

AMP-binding (9..450): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: alaaaGaAVK
Nearest Stachelhaus code:: pip
Stachelhaus code match:: 40% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_37 - Region 1 - NRPS

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Location: 1 - 42,257 nt. (total: 42,257 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Predicted core structure(s)

For candidate cluster 1, location 0 - 42257:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (NMe-ile - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_37_10

Search NORINE for peptide: strict or relaxed

AMP-binding (495..900): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGaTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (1988..2390): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAmhvGGTaK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_37_11

Search NORINE for peptide: strict or relaxed

AMP-binding (475..892): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAenIGAItK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_38 - Region 1 - NRPS,RiPP-like

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Location: 1 - 47,146 nt. (total: 47,146 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 47146:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - val - pro - val - gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_38_10

Search NORINE for peptide: strict or relaxed

AMP-binding (42..440): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWlGGiFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 80% (moderate)

AMP-binding (1109..1506): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (2171..2574): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvAHLAK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 90% (moderate)

AMP-binding (3243..3644): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWfGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (4308..4707): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_39 - Region 1 - RiPP-like

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Location: 70,289 - 81,308 nt. (total: 11,020 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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TARA_SAMEA6035815_MAG_00000013-scaffold_47 - Region 1 - NRPS

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Location: 3,401 - 59,180 nt. (total: 55,780 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 3400 - 59180:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (asn - val - ile - asp - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_47_11

Search NORINE for peptide: strict or relaxed

AMP-binding (39..433): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGhVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

AMP-binding (1087..1484): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFfvGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 80% (moderate)

AMP-binding (2136..2530): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

AMP-binding (3186..3580): asp

NRPSPredictor2: asp

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (4232..4623): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_49 - Region 1 - NRPS-like

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Location: 1 - 33,149 nt. (total: 33,149 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33149:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_49_5

Search NORINE for peptide: strict or relaxed

AMP-binding (94..528): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ityYLGtMtK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_49_9

Search NORINE for peptide: strict or relaxed

AMP-binding (29..416): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gqgvaGGPvK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 40% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_50 - Region 1 - NRPS

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Location: 1 - 28,079 nt. (total: 28,079 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 28079:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal) + (D-leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_50_3

Search NORINE for peptide: strict or relaxed

AMP-binding (271..668): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAlmaGLIaK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_51 - Region 1 - NRPS,T1PKS

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Location: 1 - 61,928 nt. (total: 61,928 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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TTA codons

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 61928:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (NMe-X) + (mal - D-ser) + (X - X) + (D-glu) + (NMe-ser - ser) + (asn - X) + (mal) + (asn - asn) + (D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_51_2

Search NORINE for peptide: strict or relaxed

AMP-binding (487..880): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAwDIGVinK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_4

Search NORINE for peptide: strict or relaxed

AMP-binding (461..857): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1531..1927): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_6

PKS_AT (534..830): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 121.9
inactive: 69.2
Methoxymalonyl-CoA: 63.6
Methylmalonyl-CoA: 48.6
Isobutyryl-CoA: 29.6
Propionyl-CoA: 24.5
Benzoyl-CoA: 24.2
Acetyl-CoA: 20.9
CHC-CoA: 15.6
trans-1,2-CPDA: 14.7
fatty_acid: 12.2
2-Methylbutyryl-CoA: 11.4
3-Methylbutyryl-CoA: 9.3
Ethylmalonyl-CoA: -1.5

TARA_SAMEA6035815_MAG_00000013-scaffold_51_7

Search NORINE for peptide: strict or relaxed

AMP-binding (508..914): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

AMP-binding (1575..1984): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DgeHSGlVtK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_8

Search NORINE for peptide: strict or relaxed

AMP-binding (475..872): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

AMP-binding (1953..2352): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_9

Search NORINE for peptide: strict or relaxed

AMP-binding (481..879): glu

NRPSPredictor2: glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DsKDLGVVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_11

Search NORINE for peptide: strict or relaxed

AMP-binding (467..878): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAvDLGsVaK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 70% (weak)

AMP-binding (1548..1949): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAmHvGgLCK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_12

Search NORINE for peptide: strict or relaxed

AMP-binding (1323..1732): ser

NRPSPredictor2: ser

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHISLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_51_13

Search NORINE for peptide: strict or relaxed

AMP-binding (598..1011): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeItAdDK
Nearest Stachelhaus code:: arg
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_54 - Region 1 - RiPP-like

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Location: 51,586 - 58,582 nt. (total: 6,997 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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TARA_SAMEA6035815_MAG_00000013-scaffold_55 - Region 1 - NRPS-like

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Location: 1 - 21,451 nt. (total: 21,451 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

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Show module domains

TARA_SAMEA6035815_MAG_00000013-scaffold_61 - Region 1 - terpene

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Location: 14,507 - 36,495 nt. (total: 21,989 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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TARA_SAMEA6035815_MAG_00000013-scaffold_63 - Region 1 - cyanobactin

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Location: 1 - 13,674 nt. (total: 13,674 nt) Show pHMM detection rules used

Region on contig edge.

cyanobactin: (cyanobactin_synth or TIGR03678)

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TARA_SAMEA6035815_MAG_00000013-scaffold_65 - Region 1 - NRPS-like,RiPP-like

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Location: 24,586 - 47,152 nt. (total: 22,567 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

TARA_SAMEA6035815_MAG_00000013-scaffold_66 - Region 1 - NRPS-like,T1PKS

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Location: 7,440 - 46,946 nt. (total: 39,507 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 7439 - 46946:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_66_21

CAL_domain (35..485): pk

minowa: NH2

Prediction, score:

NH2: 128.6
fatty_acid: 20.5
Acetyl-CoA: 1.6
AHBA: 1.4
shikimic_acid: 0.0

PKS_AT (1202..1493): mal

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 91.7%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 190.6
inactive: 136.2
Methoxymalonyl-CoA: 72.8
Methylmalonyl-CoA: 63.6
Propionyl-CoA: 42.3
Isobutyryl-CoA: 37.1
Ethylmalonyl-CoA: 28.4
Benzoyl-CoA: 24.5
2-Methylbutyryl-CoA: 20.8
Acetyl-CoA: 16.8
trans-1,2-CPDA: 16.2
fatty_acid: 12.5
CHC-CoA: 10.1
3-Methylbutyryl-CoA: 8.5

TARA_SAMEA6035815_MAG_00000013-scaffold_68 - Region 1 - lanthipeptide-class-iv

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Location: 1 - 18,995 nt. (total: 18,995 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

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Lanthipeptides

Lanthipeptide predictions

Lanthipeptide(s) for TARA_SAMEA6035815_MAG_00000013-scaffold_68_8 - Putative Class III

TARA_SAMEA6035815_MAG_00000013-scaffold_68_7 leader / core peptide: MNSILSLQRLEGAADGAAC - DhbQNDhaDhbQDhaCQDhaHADhaCNDhaAGDhaHALDVLNPIDGGGGVGVDhaPVGGGGFG

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_68_7 - Class III

Cleavage pHMM score: -2.40

RODEO score: 0

Monoisotopic mass: 4020.9 Da

Molecular weight: 4023.2 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 4041.2 Da N = 1; 4059.3 Da N = 2; 4077.3 Da N = 3; 4095.3 Da N = 4; 4113.3 Da N = 5; 4131.3 Da N = 6; 4149.4 Da N = 7

TARA_SAMEA6035815_MAG_00000013-scaffold_69 - Region 1 - cyanobactin

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Location: 3,432 - 26,191 nt. (total: 22,760 nt) Show pHMM detection rules used

cyanobactin: (cyanobactin_synth or TIGR03678)

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TARA_SAMEA6035815_MAG_00000013-scaffold_76 - Region 1 - RiPP-like

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Location: 8,048 - 19,955 nt. (total: 11,908 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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TARA_SAMEA6035815_MAG_00000013-scaffold_77 - Region 1 - NRPS,RiPP-like

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Location: 1 - 31,448 nt. (total: 31,448 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 31448:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_77_7

Search NORINE for peptide: strict or relaxed

AMP-binding (512..912): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGgTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (1573..1975): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHLgLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 90% (moderate)

AMP-binding (2639..3035): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAfHFGStyK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_80 - Region 1 - NRPS

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Location: 1 - 23,839 nt. (total: 23,839 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

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regulatory genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23839:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_80_1

Search NORINE for peptide: strict or relaxed

AMP-binding (647..1040): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DAmvlAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_87 - Region 1 - NRPS,T1PKS

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Location: 1 - 27,147 nt. (total: 27,147 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27147:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (NMe-X - thr) + (ohmal) + (X) + (D-ile - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_87_1

Search NORINE for peptide: strict or relaxed

AMP-binding (505..933): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DiWeMtadDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 50% (weak)

AMP-binding (2004..2413): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_87_2

PKS_AT (534..823): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 79.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 182.8
inactive: 112.6
Methoxymalonyl-CoA: 80.6
Methylmalonyl-CoA: 62.0
Propionyl-CoA: 40.3
Ethylmalonyl-CoA: 37.6
2-Methylbutyryl-CoA: 37.1
CHC-CoA: 27.3
fatty_acid: 23.4
Benzoyl-CoA: 21.9
Isobutyryl-CoA: 21.0
Acetyl-CoA: 20.5
trans-1,2-CPDA: 16.4
3-Methylbutyryl-CoA: 12.7

TARA_SAMEA6035815_MAG_00000013-scaffold_87_4

Search NORINE for peptide: strict or relaxed

AMP-binding (8..414): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVrHLaLLaK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_87_5

Search NORINE for peptide: strict or relaxed

AMP-binding (497..896): ile

NRPSPredictor2: ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: ile

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGVTFK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 100% (strong)

AMP-binding (2009..2410): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6035815_MAG_00000013-scaffold_88 - Region 1 - NRPS

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Location: 1 - 25,162 nt. (total: 25,162 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 25162:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - pro - X - ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_88_4

Search NORINE for peptide: strict or relaxed

CAL_domain (45..486): pk

minowa: NH2

Prediction, score:

NH2: 151.7
AHBA: 12.3
fatty_acid: 9.7
shikimic_acid: 0.0
Acetyl-CoA: -2.6

AMP-binding (1187..1604): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DPenysVVhK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 50% (weak)

AMP-binding (2737..3142): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFvAqVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)

AMP-binding (3819..4225): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAeHlGSVtK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

AMP-binding (4915..5315): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHvSLIEK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6035815_MAG_00000013-scaffold_93 - Region 1 - NRPS

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Location: 1 - 19,988 nt. (total: 19,988 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 19988:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (thr - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_93_1

Search NORINE for peptide: strict or relaxed

AMP-binding (550..960): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (1651..2053): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAgFmGfVgK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

AMP-binding (2728..3137): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvENcGtIaK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6035815_MAG_00000013-scaffold_116 - Region 1 - T1PKS

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Location: 1 - 6,820 nt. (total: 6,820 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 6820:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6035815_MAG_00000013-scaffold_116_2

PKS_AT (548..864): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 70.8%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 140.0
inactive: 82.8
Methoxymalonyl-CoA: 70.0
Methylmalonyl-CoA: 63.6
Ethylmalonyl-CoA: 54.6
Propionyl-CoA: 35.0
Benzoyl-CoA: 34.5
Isobutyryl-CoA: 32.1
2-Methylbutyryl-CoA: 24.3
trans-1,2-CPDA: 23.3
fatty_acid: 20.4
CHC-CoA: 18.4
Acetyl-CoA: 18.4
3-Methylbutyryl-CoA: 10.8