LOCUS       DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3 21218 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3.
ACCESSION   DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3
VERSION     DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2023-03-03 15:00:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 274140
            Orig. end    :: 295358
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21218
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[284140:285358](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11218
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..21218
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21218
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             7747..9714
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_214"
                     /conf="100.00"
                     /cscore="86.81"
                     /gc_cont="0.563"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_214"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 304.6; E-value: 2.4e-92)"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="9.19"
                     /score="99.79"
                     /score="99.8"
                     /sec_met_domain="Asn_synthase (E-value: 8e-48, bitscore:
                     158.1, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 8.2e-21, bitscore:
                     68.5, seeds: 307, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="12.98"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MSGLCCLIHLDGEVADQKLVRAMAEAASHRGPVTESSLDSGSATF
                     ALQGAAQHSFLAGKSQGTSSTDGAIHVVCDAILHNRQDLLACLEVDKSLRPERTWASAE
                     LDDAALILLAYLRWGAECADKLLGDFAFVIWDSEQARVLAARSSFGVKPLYYARLGQTL
                     CLASEAQQLLRHPGVSLEIDEIALADYLVDDTRNERRTFFRSINRLPAAHSLVVNSERT
                     HEERFWKLESVPDLVYRREEEYAEHLLEHLQVSINSRIEGNSEPVGVFMSGGLDSCTVA
                     SLCQQRFSESGTPQRLKAMSYGFPHLHHCSESFYISAMATELGIDSTYFDAETEWLLRR
                     PEDHQPNLETPFQGWEGVDGQIFSSLEGQGASVALTGLGGDNLFQGSVRIFRSLLRRGR
                     FGNALRGLKQHGGGLGLSLPRSVYRYVLGPALPSWLDQSFRSALGRAAKPKVPPWIEPE
                     FARRTGLLERLHREPSQQFEDPAKQAQYEMIIGLESVGRACSWLERKAAPYGIETRHPF
                     MDRRLAEFALSVPPEQHYAGLERKALLRRAMVGRLPESVRSRQGKTAFGDFFDLGLRDR
                     ERGRVEALIRDSRLADLRLVNVTRLKKAYEEYCQGGGSELRNLLWYFVTLELWLKRYTE
                     GSSGDIRVRERPNWTLSQGN"
                     /tscore="4.69"
                     /uscore="-0.90"
     CDS             9783..9965
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_215"
                     /conf="95.77"
                     /cscore="4.24"
                     /gc_cont="0.514"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_215"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="6.62"
                     /score="13.57"
                     /score="13.6"
                     /source="Prodigal_v2.6.3"
                     /sscore="9.34"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MDVISKGKLGSGKSDSLTSSAGARKAYKAPELVEWGDILDLTQGT
                     FNGTQDGFLSGTIGS"
                     /tscore="3.38"
                     /uscore="-0.66"
     CDS             10001..11218
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_216"
                     /conf="100.00"
                     /cscore="57.81"
                     /gc_cont="0.567"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_216"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGA/GAG/AGG"
                     /rbs_spacer="11-12bp"
                     /rscore="-2.26"
                     /score="59.51"
                     /score="59.5"
                     /sec_met_domain="PF05402 (E-value: 1.5e-10, bitscore: 35.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.6e-11,
                     bitscore: 36.7, seeds: 25, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="1.70"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MVREGFPSSGLRPNFSSGRDNIDWLPLEVSPEALANYGQELGLEG
                     SAVATALAQAVSSSPVWEQLPQTILAVKASSHPAFVFVGSFRDRDKPLLSSLLENLGCA
                     CAHLRYLSYSEAEAQCRLLASQLLGLFGRERLARARFQAIPRGGIIVLGMLAQILGLDA
                     EQLEQSSSEAELVVVDDCALSGSRFRDFLGKSQARSVIFAHLFSHPALRDAIEKQEPRV
                     AACVSSCDLAARDLLSEQETAGWRHRWEKRLGSKRYWLGRLDHICFPWTEPDRLVWNPA
                     EGRTELAWRIVPPELCLKNRAAEDSIAAEVQVLSEGQGPYSLGDRVFYARQKDRTLVVN
                     LATGNCLNLENVARDMWHLLLEQGDLRTVTECLLDRYEIDQNVLESDLGKFLDGLLLKG
                     LLKQAP"
                     /tscore="4.69"
                     /uscore="-1.63"
     CDS             11215..12210
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_217"
                     /conf="100.00"
                     /cscore="63.63"
                     /gc_cont="0.579"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_217"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGxAGG/AGGxGG"
                     /rbs_spacer="3-4bp"
                     /rscore="5.03"
                     /score="64.93"
                     /score="64.9"
                     /source="Prodigal_v2.6.3"
                     /sscore="1.31"
                     /start_type="TTG"
                     /transl_table=11
                     /translation="LSVLTTYDLFGLRLTTSFPFATHLEIAPGQPGIPFEIVSEAPLSW
                     DPTTLEVAYRSPMLGEDGETILRIYRLGEVDVLSFTEVADFYLFPEKIIAYPVKVEEFV
                     SSVLVEIRLLGAVMAYLLEKRGMPALHASAVVIGNSAVGFLGSNRGGKTSLAASFVENG
                     SSLLTDDILAVEDTGNEMMARSGYPQMRMWPPVAEHFLGPRWSDLPTVHPDLSKRRVGV
                     GSQLGGWGRFCTEPRPLRRLYLPQRLEDQDADETIQIKALSPRNSVIELIRHSFLPTLT
                     AGLGWEGRRLGLLSKVAEKLQVCRLTYPSGFQHLDRVRESVVADLGSGAG"
                     /tscore="-6.28"
                     /uscore="1.26"
     CDS             complement(12196..13776)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_218"
                     /conf="100.00"
                     /cscore="129.77"
                     /gc_cont="0.571"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_218"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 182.8; E-value:
                     2.2e-55)"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGA"
                     /rbs_spacer="5-10bp"
                     /rscore="7.11"
                     /score="140.48"
                     /score="140.5"
                     /sec_met_domain="Bac_transf (E-value: 2.4e-47, bitscore:
                     155.0, seeds: 461, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="10.71"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MWWSKSKTSAGFMEKEASPGLDVSSSLNHSGLPRWVDFLSSFLGL
                     LLISPLLLAVAAAVACSSRGPILFRQQRVGRGGKPFTFYKFRSMYHNPEGLPLTASGDS
                     RVTPLGKVLRKLKLDELPGLVNVLKGDVSLVGPRPEVPRFVDLNDPLWQEVLKAKPGVT
                     DPVTLRLRNEEELLGALEGDPELFYTLYLLPFKLRGYCSYLSQRTWRSDLWVLWNTFLG
                     IIFPGRNPPPTSDELANLWSEDTQTLETSSTKRSFLASYQRQLQFLLDLAVLASAFLLA
                     YLLRYEFSIPDTERSRVLVQLPAVLLIQLSAYFLAGIHNFVWRYISLSEVQAFVRAGLT
                     SAVPLVALRLGLASRFQSWRVPLSIIVLDAILAFGGLLALRVARRMSYEKQLRQRLART
                     HASEEAKKVLLVGAGQAGVLATRELENRADLRLEIKGFIDDDPLKQGTLIRGVRVLGTT
                     EDLPRLVSSLKIHHVIITIADATPLELSRILETCHKVPIPARIIPGLFEILDGSVEVSR
                     QPRASSTSP"
                     /tscore="4.69"
                     /uscore="-1.09"
     CDS             complement(13724..14944)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_219"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-170). E-value:
                     4.3e-08. Score: 24.4. Matches aSDomain:
                     nrpspksdomains_DHAR22-1_SAMN20209033_MAG_00000083-scaffold_
                     3_219_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /conf="100.00"
                     /cscore="80.57"
                     /gc_cont="0.583"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_219"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     331.4; E-value: 1.2e-100)"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGA/GGAG/GAGG"
                     /rbs_spacer="11-12bp"
                     /rscore="0.63"
                     /score="85.90"
                     /score="85.9"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.3e-102,
                     bitscore: 335.3, seeds: 38, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="5.33"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MKVPFFRPDLPEEEIQEVVDTLRSGWLTTGPKVKRFEQEFASAVG
                     ARHAIGLNSCTAALHLGVHSLGLGPGQAVLVPTMTMAATAEVIRYEGAVPILVDCDPHT
                     LNLDLEDAERKVRALHRGELPESLGSDLQLVGIVPVHVGGQMLDLEALEGFARRHSLWI
                     VEDAAHAFPAAWRSTASSPWRRCGENTAAVTCFSFYANKTITTGEGGMAVTDDDELAAR
                     IRLLSLHGLSADAWGRFSGTGSWDYRIVAPGYKYNLSDIAGALGIHQLARAEALKEKRA
                     ERASEYLAALAEVEELELPVILENRLHSWHLFLIQLRLERLNIDRAAFSVELGRRGIGH
                     SVHWRPLHLHPYYESTFGWRPEHLPVASRNWLRILTLPLFPTMTRKELRYVVEQIKDLC
                     RIHGKRS"
                     /tscore="4.69"
                     /uscore="0.66"
     aSDomain        complement(14435..14845)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DHAR22-1_SAMN20209033_MAG_000000
                     83-scaffold_3_219_Aminotran_1_2.1"
                     /evalue="4.30E-08"
                     /label="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_219_A
                     minotran_1_2.1"
                     /locus_tag="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_2
                     19"
                     /protein_end="170"
                     /protein_start="33"
                     /score="24.4"
                     /tool="antismash"
                     /translation="KRFEQEFASAVGARHAIGLNSCTAALHLGVHSLGLGPGQAVLVPT
                     MTMAATAEVIRYEGAVPILVDCDPHTLNLDLEDAERKVRALHRGELPESLGSDLQLVGI
                     VPVHVGGQMLDLEALEGFARRHSLWIVEDAAHA"
     CDS             complement(15469..16632)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_220"
                     /conf="100.00"
                     /cscore="35.58"
                     /gc_cont="0.609"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_220"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAG/GAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="5.20"
                     /score="45.34"
                     /score="45.3"
                     /source="Prodigal_v2.6.3"
                     /sscore="9.77"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MPGDPSQEKQQKNGEQGRLATPDEFRLLVDALQGDRSALEKAAAS
                     LEPGPIARFHRLGPALARRAFQQQPPLATPAPWRLAFQQSTARQLLFQRHLLLVGEQLA
                     ESRIPWLPIKGLDLCSRVYGSPEDRPAGDIDILVPPDRLAEARTALESSGWKGAFHGHR
                     YESFLADEGYCWLAAQPDGSQLEVHFRFWGMIPEGYPGDLFQRSLEAPSLGASARRAGL
                     EDAYLLAAVHAWMTPPPRPLLHWWDLERIAAKEPQGIGQQVPRLARQWHLELPVALASA
                     QAATLWPDKVHGAIAKQLVSSLRRPERLVFNRAKREGSDSISLPRMTLARLCASRSSRS
                     GWKALGRRLWAHPGIVDRETPERWQWPVRRLVHLGRRVGLPFFTSPP"
                     /tscore="4.69"
                     /uscore="-0.98"
     CDS             complement(16671..17417)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_221"
                     /conf="100.00"
                     /cscore="44.46"
                     /gc_cont="0.622"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_221"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 65.1; E-value:
                     1.1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGA/GAG/AGG"
                     /rbs_spacer="5-10bp"
                     /rscore="-0.37"
                     /score="47.66"
                     /score="47.7"
                     /source="Prodigal_v2.6.3"
                     /sscore="3.20"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MAHQEERDRILQEYERRAREIDPTLYAPWNPAEEFMRAGRRRWAL
                     RLLRRQHCFPEPSDSILEIGYGNLGWLGEMLAWGILPENLHGIELDPKRAAQARRTLPT
                     SDLQIGDARQLPWPSNSFALAIASTVWTSVLDSETRQAMASEVVRVLRPGGALLWYDFR
                     VNNPRNPNVRGIGRQEIRELFHPLQGPIRSLTLAPPLARRLLPGAHWLATTLETIPLLR
                     SHLLAVLRKPSSGVVDGRTPSENQEL"
                     /tscore="4.69"
                     /uscore="-1.12"
     CDS             complement(17417..18460)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_222"
                     /conf="100.00"
                     /cscore="87.20"
                     /gc_cont="0.607"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_222"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAG/GAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="5.20"
                     /score="90.64"
                     /score="90.6"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.9e-25,
                     bitscore: 81.8, seeds: 256, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="3.44"
                     /start_type="GTG"
                     /transl_table=11
                     /translation="VSPSKPAEPTEASPRPLVSIVMPVRNEEAYIERSLGSVLAQTYPL
                     ERMEIWIADGGSTDKTRELATALGKGAPVFLIDNPRGIVSTGLNAMLEKYQGDILLRVD
                     GHCEIAPDYVERCVHYLQTRQIAGVGGPIETVGEDFLSQSIAVAMSSRFGVGDSTFRTG
                     GSEPTLADTIAFPAYHRSVLEQAGPFDEELVRNQDDEFNYRLRKAGHSLLLAPDLSSRY
                     YSRASLRSLWSQYRQYGFWKVRVLQKHPRQMRWRQFVPPVFVLALLLSLALALTPTPLR
                     PAGRWLAAGVGGSYLVANGVASVWTAQKAGWRYLGVLPAAFALLHLGYGSGFLVGLVRF
                     ARRWKKP"
                     /tscore="-5.10"
                     /uscore="2.05"
     CDS             complement(18457..19851)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_223"
                     /NRPS_PKS="Domain: AMP-binding (111-326). E-value: 2.2e-13.
                     Score: 41.4. Matches aSDomain:
                     nrpspksdomains_DHAR22-1_SAMN20209033_MAG_00000083-scaffold_
                     3_223_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /conf="100.00"
                     /cscore="75.33"
                     /gc_cont="0.603"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_223"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGA/GAG/AGG"
                     /rbs_spacer="5-10bp"
                     /rscore="-0.37"
                     /score="82.28"
                     /score="82.3"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-11, bitscore:
                     38.2, seeds: 400, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="6.94"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MNRLLLSAYQRLPYAGRCLAAGVWGRYLRSWRYGEETPSLVETAL
                     ERESWSPSTWTRWQEERTSRLLHRAVTQVPYYRNLWAKRRQQGDTRSWKVLQHWPILSK
                     ETVRRQPEAFLADDRPRSLFRVTTSGSTGTPLALWRSRRTSIAWYALVEARLRRWNGVE
                     RRQPWALLGGRLVARGAQRKPPFWVWASSLQQLYLSAFHLAPAHAKAYLNALHHHRVNH
                     LLGYASAMTSLAHILREKGLEAPALTVVISNGEPLFESQRELLLEVFRCPIRDTYGMAE
                     IASAASECSAGRLHLWPDVGFLEVIHNQSGNAAPDGQTGRLVCTGLLNEDMPLIRYETG
                     DLGALESPSAPCPCGRQLPVLARVAGRLEDLIVTPDGRRVSRFDAVFRGNLPIREAQLV
                     QHHQDSVRALLVPADGFGSKSQREVERRLRMRLGPSMGIEVEIVDKLERESSGKLRAVI
                     SEVAPP"
                     /tscore="4.69"
                     /uscore="0.96"
     aSDomain        complement(18874..19518)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DHAR22-1_SAMN20209033_MAG_000000
                     83-scaffold_3_223_AMP-binding.1"
                     /evalue="2.20E-13"
                     /label="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_223_A
                     MP-binding.1"
                     /locus_tag="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_2
                     23"
                     /protein_end="326"
                     /protein_start="111"
                     /score="41.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="EAFLADDRPRSLFRVTTSGSTGTPLALWRSRRTSIAWYALVEARL
                     RRWNGVERRQPWALLGGRLVARGAQRKPPFWVWASSLQQLYLSAFHLAPAHAKAYLNAL
                     HHHRVNHLLGYASAMTSLAHILREKGLEAPALTVVISNGEPLFESQRELLLEVFRCPIR
                     DTYGMAEIASAASECSAGRLHLWPDVGFLEVIHNQSGNAAPDGQTGRLVCTG"
     CDS             complement(19848..20939)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_224"
                     /conf="100.00"
                     /cscore="81.54"
                     /gc_cont="0.611"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_3_224"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 48.5;
                     E-value: 1.2e-14)"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAG/GAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="5.20"
                     /score="92.72"
                     /score="92.7"
                     /sec_met_domain="Glycos_transf_1 (E-value: 8.5e-13,
                     bitscore: 42.6, seeds: 63, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="11.18"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MKKVSTRQQGGVPSPLNSGKTTPGPPLKVLVVTSEWPTPENPTFV
                     PFLVEQVAALREAGIAVEVFPFRGANNPANYNRARRQLRQRWDLESFDLIHAQFGQSGL
                     VVGKTETPLVVTFHGSDLHGIVGEGGGYTLKGRLLRTASRRVARRATRVILVSWHLSAF
                     LPMHTPFDVIPCGIDLEKFRPMARGEARSELGLPQEDPLVLFASSPRNPVKRFGLAQKV
                     MESLGEESPAQLLTLEGIPHERVPLYMNACDALLMTSRHEGSPMVIKEALACNLPVVSL
                     AVGDVADRISAVEGCVLCRSEVPGDLATALSPLLQEPRRVSGRSAVADLDHSILTPKIL
                     SSYRTTLALRNPGALSANSEPRS"
                     /tscore="4.69"
                     /uscore="-1.34"
ORIGIN
        1 aacaattccg aatcacttct gaccccgcgg atccggtgcc tgccgatgcc gtggcagccg
       61 agctcccggc cggtatctat accgttagac ctatcggcgt ggatatgcag aatctcaatt
      121 tctggcgatt cttccatcca gtgctgtgtc aggacgaagc attcgctcct tgtgttcctc
      181 taaggccttt cctggtaggg gacctcgtct ggcaggacct ggacggtaac ggagtagccg
      241 atccgggtga gcctggtatt ggcggcgtcg tcatggagct tctggattcc atgggtggtt
      301 ctatcgatac agcgacgacg gacagctccg gcgcctacag cttcgaggtt gacgctggca
      361 ccttcaccgt gcgcgttgcc acttctaact tcgatcccgg tggggttctc gaaggtcaag
      421 cgagcaccac gggtggcgac gatcagaccg ataccgtaac cacgaataac gtgttgacct
      481 atgacttcgg ttatcagggc atgggaagta tcggaaactt cgtctggttc gacctggaca
      541 tggatggagt acaggatgcg ggcgagcccg ggatcggtgg cgtcaacgtc agcctgctgg
      601 aagcagggcc ggatggagat ttctttaccg gtgacgacgt tttctttcca gacatgacga
      661 ccgattccac gggcgtttac gatttcttga acctgagcgc agggaactac cgtgtcagca
      721 tcgatggcgg tagcctgccg gcgggagtca acctcaccac agggaatgag cccctcgagc
      781 tggtcctcag tttcagcgaa gacttcaacg atgcagattt tggttacgcc ggcgacggca
      841 tcatcggtga tcgtgtttgg ctcgatacca attccgacgg aatacaggac tctggagagc
      901 ctggcctaga cggagtcacc gtgaccctgg ctggggatct ggatggcgat ggcatcgaag
      961 acattacggc gacgacggtg acgacaacag ttggaaccgt cgacggcttc tatcaattca
     1021 cgggcctgcc gccagtttcc acttgtgttc ccggcggcgg gggcgacgac gacgacgatg
     1081 atgacgacga tggcggtgac ggactcggtc tgagaagcac cggggagcaa gctcgcggtg
     1141 gaagctctag tctggttcct gcctgtatgt atacggtaac ggtggtcacg accactcttc
     1201 ccgcaggcac ggatattccg actttcgact tcgatggggt cgtgactccc cacatggcaa
     1261 ccctcacctt gggtctggcg gagattcagc ccaatgtcga ctttggctac aacggactcg
     1321 gtgccatcgg cgacacggtc tggcgcgacg acaacaacaa cggtgtccag gacggtagcg
     1381 agcctggcat cagcggtgtg acggtgacgt tgcgagacag cacgaacacg gtggtagata
     1441 cagcagtcac tgacgggact ggtaactacg acttcccgaa ccttgcggca gacacctaca
     1501 cagtgaccgt agatgcggcc actctgccgg cgggtatcga tactcctacc tttgacttcg
     1561 atggcaccgg aactgccgac gtggcaacgg tggtgctggc cggcggcgag acgaataacg
     1621 acgtcgactt cggttaccgg ggtgacggag tcatcggcga cacgatctgg cgcgatgaca
     1681 atggcaacgg tgtccaggac ggtagcgagc ctgggatcgg cggcgtgacg gtgacgttgc
     1741 gggatagctc gaacaacgtg gtcggtacgg cggtgacgga cggcaacggg aactacagct
     1801 tcccgaacct cttgccggac acctacacgg tgacagtgga cccggcgacc ctgccttccg
     1861 gagtcaacgt tccgacgttt gacttcgacg gtacgggaag tccgaacacg gcttctgtgc
     1921 ccctaggcgc caacgagacg aacaacgacg tcgacttcgg ctaccgaggg gacggctcga
     1981 tcggcgacac ggtctggcgt gacgacaatg gcaatggtgt ccaggacggt agcgaacctg
     2041 ggctcggcgg cgtgacggtg acgttgcggg acagcttgaa caacgtggtc gatacggcag
     2101 tcacggacgg caacgggaac tacagtttcc cgaacctggc ccctgacacg tacacggtga
     2161 cggtggatgc ttccaccctg cctaccggaa tcacgactcc tacttttgac ctggacggca
     2221 cgggcactgc gaatgtcgca tcggtggctt tgggagccgg cgagacgaat aacgacgtcg
     2281 acttcggcta ccagggcgat ggtgccatcg gcgacacggt ctggcgcgac gataatggca
     2341 acggtgttca ggatggaacg gagcctggga tcggtggcgt gacggtgacg ttgcgggata
     2401 gctcgaacaa cgtggtcggt acggcagtga cggacggcaa cgggaactac agctttccga
     2461 acctggcccc tgacacgtac acggtgacgg tggatgcttc taccttgcct gccggaatca
     2521 caaccccgac gttcgatctg gatggcacgg gtaccgcgaa tgttgcagca gtcgctttgg
     2581 gtgccggtga gacgaacaac gacgtcgact tcggctacca gggtgatggc gccatcggtg
     2641 acacgatctg gcgcgatgac aacggcaatg gtgtccagga cggtagcgag cctgggatcg
     2701 gcggcgtgac ggtgacgttg cgggatagct cgaacaacgt ggtcggcacg gcggtgacgg
     2761 atggcaacgg aaactacagt ttcccgaacc tggttcccga cacctacaca gtgacggtgg
     2821 atgcttcgac cctgccggct ggtgttacga ctccaacctt tgacctggac ggaacgggca
     2881 cggcaaacgt tgcagcagta actttgggtg ccggcgagac gaataacgac gttgacttcg
     2941 gctaccgggg tgacggcgcc atcggcgaca cgatctggcg tgacgacaac gacaatggtg
     3001 tccaggacgg aagcgagcct gggatcggtg gcgtgacggt aacgctgcgg gatagctcga
     3061 acaacgtggt cggtacggcg gtgacggatg gcaacggaaa ctacagtttc ccgaacctag
     3121 ttcccgacac gtacacggtg acggtggatg cttccactct gccggctggt gttacgactc
     3181 caacctttga cctcgacgga acgggcacgg caaacgttgc agcagtaact ttgggtgccg
     3241 gcgagacgaa taacgacgtt gacttcggct accggggtga cggcgccatc ggcgacacga
     3301 tctggcgtga cgacaacgac aatggtgtcc aggacggaag cgagcctggg atcggtggcg
     3361 tgacggtaac gctgcgggat agctcgaaca acgtggtcgg tacggcggtg acggatggca
     3421 acggaaacta cagtttcccg aacctggctc ccgacacgta cacggtgacg gtggatgctt
     3481 ctaccttgcc tgccggaatc acgactccga cgttcgatct ggacggaacg ggtaccgcaa
     3541 acgttgcagc agtaactttg ggtgccggcg agacgaataa cgacgttgac ttcggctacc
     3601 ggggtgacgg cgccatcggc gacacgatct ggcgtgacga caacgacaat ggtgtccagg
     3661 acggaagcga gcctgggatc ggtggcgtga cggtaacgct gcgggatagc tcgaacaacg
     3721 tggtcggtac ggcggtgacg gatggcaacg gaaactacag tttcccgaac ctggttcctg
     3781 acacgtacac ggtgacggtg gatgcttcca ctctgccggc tggtgtcacg actcctacct
     3841 ttgatctgga tggcacgggt acggcgaacg tcgcatcggt ggctttgggt gccggtgaga
     3901 cgaataacga cgttgacttc ggttaccggg gtgacggagc tatcggcgac acgatctggc
     3961 gtgacgacaa cggcaacggt gtccaggacg gaacggagcc tgggctcggt ggtgtgacgg
     4021 taacgctgcg ggatagctcg aacaacgtgg tcggtacggc agtaacggat ggcaacggaa
     4081 actacagctt cccgaacctt cccccggaca cctacacggt gacagtcgac ccgtcgacgc
     4141 tgcctgccgg agtgagcgtt ccgaccttcg atctggacgg aacgggcacc ccgaatgttg
     4201 cggcggtcac gatcggtgct ggcgagacga acaacgacgt tgacttcggc taccaggaag
     4261 aagtggtctt gggttccatc ggcgatcgag tctgggaaga cttgaatggc gatggctctc
     4321 aggacgtcgg tgaggtcgga atcaataacg tgacggtgaa cctgctggac ggcggagcaa
     4381 tcgtcatcga tacgcaggtg acttccggtg acggcaacta cctgttcagt ggtctaccgg
     4441 cggggagcta caccgtcgtt gtggatgcca ctaccttgcc gggtggtctc gcccagacct
     4501 tcgatctaga tggccttgct acggcaaatc aggcctccct ggtactcgga gatggagaga
     4561 acaatgccct cgtcgacttt ggttatgggc cttgtggcga gtgtgatggc aaagttaccg
     4621 agttgaccct gcaataccta gggtcgtcgg ctgcgaacat tgaggttgtt gcccggcggg
     4681 ggcccactac cgacacagtg ttcactggca ccctcaatcc tggggatacc tttgacctgg
     4741 tgggtccgca aaccggtaac ggtggtttct ttggaacctt gggaacggag attcgaatct
     4801 tcgtcgacgg agttcatcag accaccattc acaccagttg ctcggttccc gttgggcctg
     4861 gtttgatcag cggagacttc aaagtgttgg caggcgccag tcgccatggt ggccttttgt
     4921 gtcccgttga cgatccgggt ggacctggtg acgactgtgg ctgcgaaggc aaggtcgctt
     4981 cattgaagat gcagtacacc ggagccacca ccgcctttat cgaggtggtc ggccagggtg
     5041 gcccgaacac ggaaacgctg tttagtggaa atgtcgcgcc cggcggaatg ttcgacgtga
     5101 ccagcttcac gaccgcaaac cccggattcg agggcaccgt gggcaccgag atcgacctgt
     5161 tcgtcaacgg tgtcttgcag accaccatcc atacgagttg ctctcaaccc atcggtccgg
     5221 ggctggtgag tggggacttc ctggttcttg gaggcttcag ccgggatttc gacggtccct
     5281 tatgccctgt cgagggggat ggcactgagt actgcgtaag cccagcggag ggagatgtct
     5341 tcaactcggg atcaggcggc cacgcgctgt ggcttcccgg tatcagtcaa gagctcatct
     5401 tcgacggagg tggcggtact ttcgttcaga actcggacgg aacggccagt ctcacgggga
     5461 ctctctctga tgaagcggac agctcgaaac agtttctcgt cagtgtgcag ttcactggcc
     5521 tgaccttcat cactcctcct ggcagtccaa agaaagaact cgatcccaac gcctatagcg
     5581 agaatggcgg tccggtggat accgattctt gggtctacta caccggattt accgggagtc
     5641 tcataggcgc cggtagctgg gctggagcag aggtaacctt ctctctgacg ggctcagcat
     5701 tccagctcgg agttggagcc aatgggaaga atgtgaactt cggcggctct ggttggtttg
     5761 attggtcggt gactagtcaa ccgagcggag gggggtttcc ttccactggc cgtggggaca
     5821 tcaacatcga tctaaacgtc ggcgcctgcc ccgacggtgg cggttgtccg gatgacttgg
     5881 attttgagat cgatgccagt ggcaacggcc tggtccgagg tcagatcatc gatgatgagt
     5941 tcgcttctct gggaatccac atcaccacca acgatccaac caaccaccct gcgatgatct
     6001 tcgatagtgg aaatccgacc ggtggagacc ttgatctggg aactcctcat caggacttcg
     6061 gaggtcccgg gatcggcgct ggcggagcga gcggtcaggc aggacaaaac aacttaccgt
     6121 tgggcaagct gttgatcatt tctgaggatg gagatcaggg cgacccagat gacaacgctg
     6181 gcggaggaga tttcattttc accttcgact ctccggtgga gatcgcctct gtgaccctcg
     6241 tggatatcga cctcaacgag cccgccgcag tggaagtctt cgacgagaac ggaagtctga
     6301 tctcccaggc cggcatgctg gccttgggtg acaatagcgt tcaggtcgta gaggttgctg
     6361 ctgcgggagt ccgccgcctc gagattcact tccccagcag tggcgccgta gcagggatta
     6421 gtttcggcgg cgactgccca ggtggtggtg gcggtggtgg tgactgcacc cccggcaagg
     6481 tgagggacga tttcgatacc gtctctttca gcaacaacga cggacccgac gactggtctg
     6541 gcgattgggt cgagaacgat ccggcggggc caggaccgaa ttcgggtcgg gtctacatgc
     6601 aaccgggctt cctcttcttg aacgacgctc cggacaccgg cggtgagccg agtgtggccc
     6661 gcgaggtcga tatggaagga gctgccagcg cgaacctgag gttcaagttc gacaccggct
     6721 ccggagtcga tgcgagcgat gccattaccg tggagatctc caacaatgga ggagccacct
     6781 ggaccaccct cgaagtgatc accggaatca acggaaccat caccggctcc agggatttcg
     6841 atatcaccag tcatatctct gccaacaccc aggtgcggtt ccgggtcacc aacctatacg
     6901 gtggcgacca cgagttcttc tgcctgcagt gggtcgagat cacctggacc tgcgacgatg
     6961 agccggatcc tcttggctcg atcagtggca cggtgtggga cgacgccaat ggcaatggtc
     7021 agcaggacga tccgtctgcc ggtctcggtg gagtcaccgt gaagctcaag cagggcagca
     7081 cggtcctaga caccaccacc acggacggca atggtgacta caccttcggc gatctggagg
     7141 ctggtgacta tacggtcaag gtgaccgctt cgagcctgcc ggatggcatc gacaacccga
     7201 cctatgacct ggacgggact ggtactgccc atcgggctga tgtcagcctg agcagcggtc
     7261 aagatcggaa cgatgccgat ttcggttacc agggttcgac gacctgctcc tattgcgatc
     7321 actacacggg gtctctgtgg gatgcaggcg actacgagtg ggaaccggat ggcacctact
     7381 actggagtgg ggctggcacc caggaaggtt ggctggaagg agctgctggt tcggacttcg
     7441 acctctacct ctacaagtgg aatgggtcgg cctgggaagt cgtagccagc tcctacagcg
     7501 acgctacctc gtcggagcac attagctata acggctccga gggtcactac atgtggttgg
     7561 tctacaacta cagcgggtct ggcgactacg acctctggct agaccaccct tagacaagac
     7621 aagctcagcc ttctctagga atgaaagctg agcctgtcaa cgaatcgttt tctacacagc
     7681 cggtcgagcg tgagctcggc cggctttttg gagtcagccg agcccacgct cgggaggcat
     7741 agcctgatga gcggactctg ttgtctgatc cacctggatg gcgaggtagc tgaccaaaag
     7801 ctggttcgag ccatggcgga ggcggcatcc catcgcgggc ctgtgacgga gagttccttg
     7861 gactccggtt ccgcgacctt cgcgctgcaa ggagccgctc agcattcttt ccttgccggg
     7921 aaatctcagg ggaccagttc aactgatgga gccatccatg tggtttgcga cgccattctt
     7981 cacaaccgcc aggacctact cgcctgccta gaggttgata aatctcttcg gccagaaagg
     8041 acatgggctt cggctgagct cgatgatgct gccttgattc ttctggccta tctccggtgg
     8101 ggagcggagt gtgcggacaa gcttctcggg gacttcgcct ttgtgatctg ggactcagaa
     8161 caagcgcgcg tcctggctgc tcgaagttcc ttcggggtca aacctctcta ctacgcccgc
     8221 ctggggcaga ccctttgctt agcctccgag gctcaacaac ttcttcgaca ccctggggtt
     8281 tctctcgaga ttgatgaaat tgcactcgcc gactatttgg tcgatgacac acggaatgag
     8341 cgccgaactt tctttcggtc gataaaccgg ctccctgccg cccattcgtt ggtggttaac
     8401 tctgagcgga cccatgagga gcgtttttgg aagttggagt ctgttccaga ccttgtctat
     8461 cgccgagagg aagaatacgc ggagcatctc ttggagcacc tccaggtttc gatcaattcc
     8521 cgcatcgaag gaaattcaga gcccgttggt gtcttcatga gtggggggct cgattcttgt
     8581 accgtcgctt ctctttgtca gcagagattc tctgagagtg gcactccaca gcggctgaaa
     8641 gccatgtcgt atggctttcc ccatctccat cactgctccg agtccttcta catttcggcc
     8701 atggcgacgg agctcggcat cgactcgact tatttcgatg ccgagactga atggctattg
     8761 cgaagaccgg aagaccatca gcccaacttg gaaacgccgt ttcaaggctg ggagggggtg
     8821 gatgggcaga tcttttcgag ccttgagggc cagggtgcgt ccgtagctct aacaggattg
     8881 ggtggagaca acctttttca gggtagtgtt cggatatttc gttctcttct ccggcgcggt
     8941 cgattcggta acgccctgag agggttaaag cagcacggtg ggggcttggg tctttctctg
     9001 cctcgctccg tatatcgata tgttctcggt ccggccttgc cgtcttggtt agaccagagt
     9061 ttccgatcgg ctttggggcg cgcagccaag cccaaggtac cgccgtggat cgaaccggag
     9121 tttgctcgcc ggacaggtct tctagaacgt ctccaccggg agccttctca gcagttcgaa
     9181 gatcccgcca agcaagctca gtatgaaatg attattggtc tcgaaagtgt gggaagggcc
     9241 tgttcctggc tcgagcggaa agcagccccc tacggcatcg agactcgcca tcccttcatg
     9301 gaccggcgtc tcgctgagtt cgccctctcg gtgcctccag agcagcacta tgccggtctt
     9361 gagcgaaagg cattactacg cagggccatg gtgggtcgat tgcctgagag cgttcgttcg
     9421 aggcaaggga aaacggcttt tggcgacttt ttcgatctag ggctgagaga tcgggagcga
     9481 gggagggtcg aggccctaat tcgagactct cgacttgccg acctgaggct ggtgaacgtc
     9541 accaggctca agaaggccta cgaggagtat tgtcaaggag ggggctcgga gttgaggaat
     9601 cttctatggt atttcgtcac cctggagcta tggctgaaaa gatacacaga gggctcctct
     9661 ggggatattc gagtacgaga gcgccctaat tggacattat cgcaaggcaa ttgagcggtc
     9721 tttgaccact ctttgatatt gtacgtgtag tgtagtttga ttttgagggg gaggacgatg
     9781 gtatggacgt gataagtaag ggtaagttgg gctctgggaa gagcgactct ttaacttcat
     9841 ctgcaggcgc tagaaaggcc tacaaggctc cggagctcgt cgagtgggga gatattctgg
     9901 atttgactca ggggactttc aacggtaccc aagatggatt cctgagcggg actatcggta
     9961 gttagttggt accttgtcag agggctgaga tcaagactga atggtgcgtg agggattccc
    10021 gagctcagga ttaagaccga acttttccag cggacgggac aacatcgatt ggcttcctct
    10081 ggaagtgtct ccagaggctt tagccaacta tggccaggag ctgggcctcg agggttcggc
    10141 tgtggcaacc gccttggcgc aggctgtgtc cagctctccg gtttgggagc aactccccca
    10201 aaccattctt gccgtgaagg cttcctcaca cccggcattc gttttcgttg ggagctttcg
    10261 tgatcgcgac aagcctctcc tctcttcttt acttgaaaat ctcggctgcg cctgtgctca
    10321 ccttcgctat ctcagctact cggaggccga ggcgcaatgc aggcttctgg ctagccaact
    10381 tctaggactc tttggccggg agcggttggc gcgggctcgg tttcaggcaa ttccgcgtgg
    10441 agggatcatc gtcctcggaa tgttggccca gattctaggc ctggatgccg aacagctaga
    10501 gcaatcttcg tccgaggcag agcttgtagt ggttgacgac tgtgcattga gcggttctcg
    10561 gttcagagac ttcctaggaa agtctcaggc aagaagcgtc attttcgccc atctcttctc
    10621 ccatccagct ttacgtgacg cgatcgaaaa gcaggagcca agagtagcgg cttgcgtcag
    10681 cagctgcgat ctcgctgcca gagatttgct ctcagagcaa gaaactgccg gatggcggca
    10741 ccgctgggag aagcggcttg gctcgaagcg gtattggcta gggcgtctgg atcatatctg
    10801 ctttccctgg accgagccgg atcggctggt gtggaatccc gccgagggca ggactgagtt
    10861 ggcctggcgt atcgtgccac cggagctctg tctcaagaat cgagcagctg aagactccat
    10921 cgctgctgag gttcaagtgc tttcggaggg ccaaggtccc tattctctcg gtgaccgagt
    10981 tttctacgca aggcagaagg acaggacatt ggtcgtgaat ctagctaccg gaaattgcct
    11041 aaatctcgag aacgtcgccc gggacatgtg gcatcttctc ctcgaacaag gagacctccg
    11101 gacggtgacg gagtgtcttc tagatcgcta cgaaatcgat cagaatgtcc tagagtcgga
    11161 tcttggcaag tttctcgatg ggttgctact caagggcctc ctaaagcagg ccccttgagc
    11221 gtgttgacaa cctacgatct tttcggcctt cgcctgacca cctcctttcc gttcgcgacc
    11281 cacctcgaga tagctcccgg gcaaccaggg atccctttcg agatcgtttc agaagctcct
    11341 ctcagttggg atccgaccac cttagaggtc gcctaccgaa gcccaatgtt gggagaagat
    11401 ggagagacga tcctgaggat ctaccgccta ggtgaggtag atgtactttc ctttacggag
    11461 gtcgctgatt tctacctctt tccagaaaag atcattgcct acccggtgaa ggttgaggag
    11521 ttcgtcagta gcgtacttgt ggagatccgg ctgttggggg cggtcatggc ctacctcttg
    11581 gagaagcggg gcatgcctgc tctgcatgca tcggcggtgg tgattggaaa cagcgctgtg
    11641 ggctttcttg ggtcgaatcg cggtggcaaa acttccctgg cagcgtcttt tgtcgagaat
    11701 ggctcctctt tgctgacgga tgacatcttg gcagtcgagg acactggaaa cgagatgatg
    11761 gctcggtctg gctaccctca gatgcgcatg tggccaccgg tggccgagca ttttctgggg
    11821 ccgaggtgga gcgatctacc tacagtccac cccgatctga gcaagaggcg ggttggagtg
    11881 ggttcgcagc ttggtggctg gggccgtttt tgcaccgaac cacggccact gcggcgcctc
    11941 taccttcccc agcgcttgga agaccaagat gctgacgaga cgatccaaat caaagccctg
    12001 tcgccccgta actcggtcat cgagttgatt cgccactcct tcctgccaac cttgaccgct
    12061 ggtttgggtt gggaggggag acggctcggg ttgctttcca aagtcgccga gaagcttcag
    12121 gtttgccggt tgacctaccc ctcgggcttt cagcacctgg accgagtcag ggaaagcgtg
    12181 gtggcggacc tgggttcagg ggctggttga agacgctcgc ggttgccggc tcacttctac
    12241 agagccgtcg agaatctcga acaatccagg gatgattcgg gctgggatgg gaaccttgtg
    12301 acaggtttcc aggatgcgac tgagctccaa gggagtcgca tcggcgatgg tgatgatgac
    12361 gtggtgaatt ttcagcgagg acactagcct gggtagatct tctgtggttc caagaacccg
    12421 cactccgcgg atcagggttc cttgtttgag gggatcgtca tcgataaagc ctttgatttc
    12481 caggcgcagg tcagcgcggt tctctagctc acgggtagcc aggacacctg cctggccagc
    12541 ccctaccaac aggaccttct ttgcctcttc agaggcatgg gtccgagcta gacgttgcct
    12601 gagctgtttc tcatagctca tgcgtcgggc tactcgaagg gccaggagtc cgccaaaggc
    12661 gagaattgca tcgagaacga tgatcgagag gggaactcgc cagctctgaa agcgggaggc
    12721 caagccaagg cggagtgcca ccaacggaac agcggaagtg aggccagctc ggacgaacgc
    12781 ctgtacctcg gagaggctga tgtacctcca gacaaagttg tgaatacccg ccaagaagta
    12841 ggcgcttagc tgaatcagga gcaccgctgg caactggacc agcacccggc tgcgttccgt
    12901 atccgggatg gaaaattcat accgtaggag gtaggccagt aagaaagcgc tcgctaggac
    12961 cgccagatcg agcaagaact ggagctggcg ctggtaagag gcgagaaagg acctcttggt
    13021 agaggaagtt tctaaggtct gggtatcctc actccacaga ttggccaatt catctgaagt
    13081 cgggggaggg ttacggccag gaaagatgat gcccagaaat gtgttccaga ggacccaaag
    13141 gtcgctcctc caggttcgct ggctcaggta gctgcaataa cctcgcagct tgaaggggag
    13201 caggtagagg gtgtagaaga gctctggatc tccttccaga gctcccaaga gctcttcttc
    13261 gttgcgaagc ctcagggtta ctgggtcagt gactcccggt ttcgctttca ggacctcttg
    13321 ccacaaaggg tcgttgaggt cgacgaagcg aggaacctcg ggtcgggggc cgaccaggga
    13381 tacatctccc tttaagacgt ttaccaggcc aggcagctca tctagcttga gcttgcggag
    13441 aacctttccc agtggcgtca cccgagagtc accactggcc gtgaggggca agccttccgg
    13501 gttgtggtac atggaacgaa atttgtagaa ggtgaagggc tttccccctc ggccgaccct
    13561 ttgctgacgg aagagaatag ggccacggga gctgcaagcg acggcagccg cgactgcgag
    13621 gagcaagggg gagatcaaca acagcccgag aaaagagctg agaaaatcga cccagcgggg
    13681 gagccccgag tggttgaggg aggagcttac gtctaacccg gggctagctt ctttttccat
    13741 gaatcctgca gaggtctttg atttgctcca ccacataccg cagttccttg cgggtcatgg
    13801 tcggaaagag agggagagtc agaatacgaa gccagtttct actagcgacg ggaaggtgct
    13861 ccggtcgcca gccgaaagtc gattcgtagt atgggtggag atgtagcggc ctccaatgca
    13921 ctgaatgacc gataccccgc cgacccaatt caacggaaaa tgcagcgcga tcgatgttga
    13981 ggcgctccag ccgcagctgg atgagaaaga gatgccagga gtgaaggcga ttttcgagga
    14041 taaccggtaa ctcgagctcc tcgacttcag ctaaggctgc caggtattcc gaggctcttt
    14101 cggctctctt ttccttcaaa gcttcggctc gagccagttg atggatgccg agcgcaccag
    14161 cgatgtccga aagattgtat ttatagcccg gagcgacgat gcgatagtcc cagctgccgg
    14221 ttccggaaaa ccgaccccag gcatccgcgg atagcccatg caacgaaagc aggcggatac
    14281 gagccgcgag ctcgtcgtca tcggtgaccg ccatgccccc ttcaccggtg gtgatcgtct
    14341 tgttggcata gaaggaaaag caagtgacgg ctgccgtatt ctccccgcag cgtctccatg
    14401 gagaggaggc tgtggagcgc cacgcagctg ggaaggcatg ggcggcatct tccacgatcc
    14461 aaagagagtg gcgccgagca aagccctcga gagcctccag gtcgagcatc tggccaccca
    14521 cgtggaccgg cacgatgccc accagctgaa ggtctgagcc cagagactca ggcaactctc
    14581 cccgatggag agcccgtacc ttccgctccg catcttccaa gtccaggttc agagtatgag
    14641 gatcacagtc gacgagaatc ggcaccgcac cttcatagcg gatcacctct gcggtagctg
    14701 ccatggtcat ggtgggtacc agaaccgctt gccccggccc gaggccgagg gaatgcactc
    14761 ccaggtgcaa ggcagccgtg caggagttga gaccaatggc gtggcgagct cctaccgcgg
    14821 aagcaaattc ctgttcgaag cgcttcacct ttggacctgt ggtcagccac ccggaccgca
    14881 gtgtgtccac gacctcctgg atctcttcct caggaaggtc tggacgaaag aacggtactt
    14941 tcatgaactc ttcaaactcc ccaattccac acccatgcct acctggtcgt ccaggggcat
    15001 ttgccgagat caaatcagaa caaagaaata tgggcttggc gcactactca gcagtccgcc
    15061 tagattcttc gaatgagcac agctttgaaa ggtcgctcga agagcgatat cgtttcatca
    15121 ccctcgaaat gacacaggaa atagcactat gtcgccatct tccagtcgta ctcccgagag
    15181 ggggccccga agtcttcctc caagacgaca ttctacaccg accctggcgg cttccgaagg
    15241 ggggccgtag agatctttct ctactagcag ggaaattgcc ccgccaatgc tgctgttagt
    15301 ggagcgaacg ttttctgctg gacacgggtt ctggctgaat ctacatcgac agcagcccac
    15361 cgtgatcctc tccggagaga ggtcctggct gtgtgacaga gagtatctcc gtccggggat
    15421 ttccaggcat cggcgttgtg tcgcgacgaa ggagcagggc aactttgact aggggggcga
    15481 ggtgaaaaag gggagtccca ctcttctacc caggtggacg agtcgtcgga ccggccactg
    15541 ccaccgctca ggggtctctc ggtcgacgat gcccgggtgg gcccagaggc gccggccgag
    15601 agccttccag ccactacggc tagacctgga ggcgcatagc cgggcaagag tcatgcgggg
    15661 aagagagata ctgtcgcttc cttctcgttt ggcacggttg aagacgagcc gttccggtcg
    15721 ccgtagactg gataccagtt gtttggcgat tgcgccatga accttgtcag gccagagcgt
    15781 agctgcctgg gcagaagcca aggctacggg aagctccagg tgccactgtc ttgccaatct
    15841 tggaacttgc tggccgatcc cttggggctc cttggctgcg attcgttcga ggtcccacca
    15901 atgtaagaga gggcgtggag ggggcgtcat ccaagcgtgg acagcggcca gtagataagc
    15961 gtcttcgagc cctgctcgtc gggctgaggc acccaaggac ggagcttcca gagatcgctg
    16021 aaaaagatct cccgggtagc cctctgggat cattccccag aaacgaaaat ggacctccag
    16081 ctgactgcca tccggttggg ccgccaacca gcaatagcct tcgtctgcga gaaagctctc
    16141 gtagcggtga ccatggaaag cgcccttcca gcccgagctc tccaaggccg tccgggcttc
    16201 ggcgagcctg tccgggggaa ccagaatatc gatatctccc gctggacgat cttccggact
    16261 tccatagacc cggctacaca ggtcgaggcc tttgattggc aaccagggga tcctcgactc
    16321 agctagctgc tctcctacta agaggagatg ccgttgaaag agcagctgcc gagctgtcga
    16381 ttgctgaaat gcgagcctcc aaggcgcagg ggtggctagg ggtggctgct gttggaaagc
    16441 tcgccgtgct agggccggtc ccaggcggtg gaaccgggcg ataggaccag gctccaagct
    16501 agcggcggcc ttctccaagg cactacggtc accttgcaag gcgtctacta acaaacgaaa
    16561 ttcgtccggg gtagctagcc tgccctgctc gccgtttttc tgctgcttct cctgacttgg
    16621 atctccaggc atctagatgg cctcgcgacg aggccggtga gagaggagct tcatagttct
    16681 tggttctctg aaggggttct tccgtcaacc actccggagc taggcttgcg cagtactgct
    16741 agcaagtgac tgcgaagcag agggatcgtt tcgagagttg tggctagcca atgggctccg
    16801 gggaggaggc gccgagctag gggcggcgct aacgtcaagg agcgaatggg gccttggagg
    16861 gggtgaaaga gctcccgaat ttcttggcga ccgatgcctc gcacattcgg gtttctgggg
    16921 ttgttgacgc gaaagtcgta ccaaagcaag gcgccgccgg ggcggagcac tcgaacgacc
    16981 tcggaagcca tggcctgacg agtttccgag tcgaggaccg aggtccagac cgtagaggcg
    17041 atggccagag cgaagctgtt ggagggccac ggcagctggc gagcatcacc gatctgaagg
    17101 tcggacgtag gaagggtccg ccgcgcttgg gccgcccttt tggggtcgag ctcgatgcca
    17161 tgaagattct cggggaggat cccccaagcc aacatctctc ccagccagcc gagattccca
    17221 tagccgatct ctagaatgga atccgagggc tccggaaagc agtgttgacg gcgcaggagg
    17281 cgcagcgccc agcggcggcg gccggctcgc atgaattcct cggcgggatt ccagggagca
    17341 tagagtgtcg ggtcgatctc ccgagcgcgg cgctcgtact cctggagaat acggtccctt
    17401 tcctcctggt gagccatcag ggtttcttcc atcgccgggc aaagcgcacc aggccgacca
    17461 gaaaaccgct gccataaccc aggtggagga gcgcaaaggc tgcgggcaag acgcccagat
    17521 agcgccagcc ggccttttga gccgtccaca cggaggcgac cccattggcc accaaatagc
    17581 tgcccccaac tcctgcggcc agccaccgac ccgcgggacg taggggcgtt ggtgtcaaag
    17641 cgagagccag gctgagaagc aacgccagga cgaaaactgg aggaacgaac tggcgccacc
    17701 gcatttgcct ggggtgtttt tgtaggactc gcactttcca gaatccatat tggcggtatt
    17761 ggctccaaag gctgcgtaag ctggcccggc tgtagtagcg ggaggaaagg tccggcgcca
    17821 ggagcaggga gtggccggct ttgcgcaatc ggtagttgaa ctcatcgtcc tggttccgca
    17881 ccagctcttc atcgaaaggg cccgcctgct ccaaaacgga acggtggtag gcgggaaaag
    17941 cgatggtgtc tgcaagggtg ggctcgcttc cgccggttcg aaaggtcgag tcaccaactc
    18001 caaagcgaga gctcatggcg acggcgatgg attgggatag aaaatcttca ccgaccgttt
    18061 ctatgggccc accgactccg gcgatctgcc gggtctggag atagtgaacg catcgctcca
    18121 cgtagtcggg agcgatttcg cagtgaccgt ccactcgcag aaggatgtct ccctggtact
    18181 tttcgagcat cgcgttgagg ccagtggaga cgatgcctcg gggattgtcg atgaggaaaa
    18241 ccggggcacc ttttcccagg gctgtcgcca actcccgggt tttgtcggta gatcccccgt
    18301 cagcaatcca gatctccatc cgctctagag ggtaggtctg ggccagcaca cttcccaagc
    18361 tccgttcgat gtaggcttcc tcgttgcgca ccggcatgac gatggatacc aggggccttg
    18421 ggctagcctc ggtaggctcc gcaggtttgg aggggctcac ggtggggcga cctctgagat
    18481 gactgcccgt aatttgccgc tgctctctcg ctccagtttg tcgacgatct cgacctcaat
    18541 tcccatcgat ggtcccagtc gcatgcgtag gcgtcgttcg acttcccgtt ggctcttcga
    18601 gccaaagcca tctgcgggca ccagaagggc gcgaacggaa tcttggtggt gctgaacgag
    18661 ttgggcttcc cggatcggca ggttccctcg aaacaccgca tcgaagcggc tcacccttct
    18721 gccgtccggg gtcacgatga ggtcttccaa gcggccagca actctcgcca agacgggcag
    18781 ttggcgaccg caagggcagg gagccgaagg cgactccagg gcgcctaggt cgccggtttc
    18841 gtaacgaatc aggggcatgt cttcgttgag aagaccggtg cacaccaaac gaccggtttg
    18901 cccgtcaggg gcggcgttcc cgctctggtt gtggatgact tctaggaagc ccacatcggg
    18961 ccaaaggtgg agccggcccg cgctacattc gctcgcagcg ctagcgatct ctgccatgcc
    19021 ataggtgtcc cgaatcgggc agcgaaacac ctcgaggagc aattcccgtt gggattcgaa
    19081 tagaggttct ccattgctga ttaccacggt caacgccggg gcttcgaggc ccttttctcg
    19141 aaggatgtgg gcgagggagg tcatggcgga ggcgtaaccg agcagatggt tgactcggtg
    19201 gtgatgcagg gcattcaaat aggcttttgc atgggctgga gccaaatgga atgccgacag
    19261 atagagttgt tggagggacg aagcccaaac ccagaagggt ggttttcttt gggcccctcg
    19321 ggcgaccaat cggcctccca acagagccca gggctgccgt ctttcgacgc cattccaacg
    19381 gcgaagcctc gcttctacca gggcgtacca ggcgatggat gtccgacggc tccgccacag
    19441 ggccagggga gttcccgtcg aaccactggt ggtcactcga aacagggacc ggggccgatc
    19501 atcggccaga aaggcctctg gttgtcgccg cacggtttct ttgctcaaaa taggccagtg
    19561 ttgcaagacc ttccaacttc gggtgtcccc ctgctgtctt ctcttcgccc acaggttgcg
    19621 gtaatagggg acctgggtga cagctcggtg tagaagtcgg gaggttcttt cctcctgcca
    19681 tcgggtccag gtgctaggag accaactttc tcgctccagg gccgtttcta ccaaggacgg
    19741 ggtctcttcg ccgtaccgcc aggagcgtag atacctaccc caaactcccg cagccaagca
    19801 acgacctgca tagggaaggc gttggtaggc ggaaaggagg aggcgattca tgacctcggc
    19861 tcagagtttg ccgacaaagc tcctgggttt ctcagggcca gcgtcgtgcg gtagctggag
    19921 agaatcttgg gagtgagaat ggagtggtcg agatccgcta ccgcgctgcg gccggagact
    19981 cgtcgcggtt cctgtagcaa aggggagagg gcagtggcta aatctcccgg tacctcagag
    20041 cggcagagaa cgcatccttc cacggccgag attcggtcgg cgacatcccc cacagccaaa
    20101 gagaccaccg gtagattgca ggccaacgct tccttgatga ccatgggaga gccctcgtgg
    20161 cgggaggtca tgagcaaagc atcgcaggca ttcatataca gtggcacccg ttcatgggga
    20221 attccctcca aggtgaggag ctgtgccggg ctttcctcgc caaggctttc catgaccttc
    20281 tgggccaggc cgaagcgctt cactggatta cggggagagg aggcgaagag gaccagcggg
    20341 tcctcttggg gcagccctaa ctcggagcgc gcttccccgc gagccattgg gcgaaatttc
    20401 tcgaggtcga ttccgcaggg aatgacatcg aagggggtgt gcatgggtag gaaggccgag
    20461 agatgccagg aaactaggat gacccgagta gcccggcggg cgactctccg acttgccgtg
    20521 cgcagtaggc gacccttgag ggtgtagccc cccccctcgc cgacgatgcc gtgaaggtcg
    20581 ctgccatgaa aggtcaccac gaggggagtc tcggtctttc caaccaccaa cccactctga
    20641 ccgaattggg cgtgaatcag atcgaaagat tccaagtccc agcgctggcg aagctgccga
    20701 cgggctcggt tgtagttggc cgggttgttg gctcctcgaa aggggaagac ctcgacggcg
    20761 attcctgctt cacggagggc ggccacttgc tctaccaaaa aggggacgaa ggtcgggttt
    20821 tcgggagtcg gccattcgct ggttaccacg agtaccttga ggggggggcc gggcgtcgtt
    20881 ttccctgagt taaggggcga agggacccct ccctgttgtc gggtgctcac cttcttcata
    20941 gtcgtcgagc ctcgcggagc ggtgaaggca ccgccgctgg ccattgtggg ggcggagcgc
    21001 cgccgctagg ggaagggtgt ttccccaagg ccctcggagg cgaaggcctg gtgctcggtc
    21061 gtcttatggg gctgacttct gccagcatca gggcggtagc taacccaaaa gtgaaggatg
    21121 gcgctgccaa gcgagtggcg gaatgaaata ggtaaagcag cgcccaggcg atcatcgtgg
    21181 cgcgaaaggc ccgggtcaac ggtggagctt tcttggcg
//
