LOCUS       DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26 22361 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26.
ACCESSION   DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26
VERSION     DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2023-03-03 15:00:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 41132
            Orig. end    :: 63493
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22361
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[51132:53493](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12361)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..22361
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22361
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(915..2201)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_37"
                     /conf="100.00"
                     /cscore="148.86"
                     /gc_cont="0.611"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_37"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.36"
                     /score="168.05"
                     /score="168.1"
                     /source="Prodigal_v2.6.3"
                     /sscore="19.19"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MWTRTSLFAIAAVAGLAVSAPSAAQLSYVKAGAVLDVEAGQLLRD
                     QVITIQDGRIVAVEAASSRKLPAEAKVIDLSKQTVLPGLIDCHTHLMSDSDDQGLRGLT
                     VSLPEATLNGVKNAAKTLQAGFTTVRMVGAPGYGDVALRDAIAKREILGPRLLVSGPPI
                     GITGGHCSDNNLLPHEYGSVGTGVADGPWEIRRRVRQNVKFGVDLIKTCSTGGVLSKGT
                     KLDATQYTLEELTALVEEAHAHGRRVAVHAHGAAGIQNAILAGADSIEHASFVNDESIA
                     LAKERGTFFVMDVYVTEHILTEGKKNGVLEESLDKEREVGTIQRENFTRAHQAGVRMAF
                     GTDSAVYPHGDNGRQFSRMVRFGMTPLEAIRTATTNAAELLGIEDRVGQLAAGFEADLV
                     AVTGNPLEDVSLLENIEFVMKGGIVYKDP"
                     /tscore="4.69"
                     /uscore="2.14"
     CDS             complement(2340..3986)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_38"
                     /conf="99.99"
                     /cscore="171.25"
                     /gc_cont="0.624"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_38"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.36"
                     /score="187.86"
                     /score="187.9"
                     /source="Prodigal_v2.6.3"
                     /sscore="16.61"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MHKWTFISFLALISFSIGAAQASPRADVVLHGGKVFTADTQGPWA
                     EAVAIRGSRVLAVGSDAEVRALEGPNTLSLDLQGRLVVPGFNDAHTHLAVGLPRLTLPP
                     INIPGPGPTLNEALAQVAGAVAIAEPGEWIVVTIGEAALFDPDTNRVALDSVAPDNPVL
                     LFTWSSHTGVVNSLGIETLGLTETEADPFGGTYGRFPGTDVLNGVANEYGLFRIFREIR
                     AQAPDELMIAQFEAFSPLLTQLGITSIQEMTVGLTRERSERVLAEADMAVRVRSMCVPL
                     TPQESCRSRQRHPLRKVRSSGIKWLLDGTPVERSAALREPYADFPGDGVLNIPTGNLIR
                     SLRRSLAEPPARNPILFHTVGDRAIDQALSAMESVAPAPVWRRRRVRLEHGDLLQQDHL
                     ARARRLGLIVVQNPTHLALDLAPALGPERAAAAQPLKTLLDNGVSLALASDGAFPNPFV
                     DIFLAVFHPFHPEEALTVAEAVTAYTLGSATAEFQEKRKGSLRRGRLADLAVLSQDIFE
                     IPPPAIPETVSLLTVVGGEIVWDSGALATQP"
                     /tscore="4.69"
                     /uscore="0.22"
     CDS             4520..4873
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_39"
                     /conf="99.85"
                     /cscore="11.15"
                     /gc_cont="0.525"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_39"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.36"
                     /score="28.38"
                     /score="28.4"
                     /source="Prodigal_v2.6.3"
                     /sscore="17.23"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MRFNLAILLGLVVFCFGAQADSISVETSPAPAEAAVQQDASTLFF
                     QTPTFLDDADAVEACPDVDADGEGAPVPIICNCLCNGVAVAVNLACRHGETCNDVNGRP
                     CNTGAGWSTYNGC"
                     /tscore="4.69"
                     /uscore="0.18"
     CDS             complement(5063..5638)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_40"
                     /conf="100.00"
                     /cscore="46.01"
                     /gc_cont="0.594"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_40"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 105.1;
                     E-value: 6.3e-32)"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGA/GAG/AGG"
                     /rbs_spacer="5-10bp"
                     /rscore="-0.37"
                     /score="51.80"
                     /score="51.8"
                     /source="Prodigal_v2.6.3"
                     /sscore="5.79"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MENSTPGHPNVHQALEHLPLETERLRLRELTLADAPFALELVNDP
                     SWIRFIGDRGIHTLDDARRYLREGPMASYAQFGLGLFLTELPESGIPIGLCGLLRRPTL
                     DAPDIGFAFLPRFWGKGYAYEAAKAVIDWSEETHAFPLVLAITLEENRSSIRLLEKLGL
                     RFEKPVRQPGDEEELRLYARRWPDRIEK"
                     /tscore="4.69"
                     /uscore="1.47"
     CDS             complement(5763..6278)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_41"
                     /conf="100.00"
                     /cscore="27.94"
                     /gc_cont="0.597"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_41"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.36"
                     /score="44.72"
                     /score="44.7"
                     /source="Prodigal_v2.6.3"
                     /sscore="16.77"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MPSMLPAKPNEVGEKPGHPVTVTLLVALLVLAGSVVFTALEARFG
                     LPDTHPSGSSPQELECQVRISPYMPRIIGEHFSTRFRIELLTSPPAVVYGEYKITYRDS
                     EGRQRTEPGVLRKAVTSSGRELYREDVALSSPVEVLSVIMLKAHCSPLEEEEPGSSPLG
                     TAKVGPRK"
                     /tscore="4.69"
                     /uscore="0.38"
     CDS             6637..9948
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_42"
                     /conf="99.99"
                     /cscore="249.77"
                     /gc_cont="0.578"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_42"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.54"
                     /score="258.19"
                     /score="258.2"
                     /sec_met_domain="Peptidase_S41 (E-value: 3e-13, bitscore:
                     41.9, seeds: 119, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="8.42"
                     /start_type="GTG"
                     /transl_table=11
                     /translation="VSQLQEGLPGIFRQPDVSESHIVFVYASDIWRVEKQGGPAQRLTS
                     VQGTESFPRFSPGGESLAFSADYTGNRDLYTLSTAGGVPQRKTFHPASDLLIDWHPEGR
                     KLLFASRRQIHNSFYSHFFEIPIEGGPATRIKIPFAADGAYSRSSKLPGRFIAFQMLGR
                     DVTLWRGYQGGLASGLFVFDTLTHRVVRLAYPNRTYAAPMWRDGDLYFISDRTDQPLKE
                     GKRNRKRIFNLWVFRGLETQLEKELEEKQIESPERLTQENEDLNFPAMGPSDMVFTQGG
                     EVFRIPFGDGTPDFGNPLRVPIELTPDRSALVPEWRPVDNLIQSFDLSSDGSRLLVSAR
                     GSIFDLPVAGGPTRLLDRFGPGSVRLESAERSAVWLDEEHILFHSDARPTQKDPSVAQA
                     SSGRSKPSEYDLVLHQIASGNEKVFHFKEGFRYRLTVSPCCHRAVFVDQTSSLQLVELD
                     THDRLVTREIGKLEGMLPYQLQRMRPCWSPTGHIVVFHDYAPNGNRRLNAVVVDSAERR
                     ILTSGFTSDCKPSFAPEGTYLYFVSRRGLHLTESELGGGAAAYSNTDRLARVQVNLAAT
                     SGSRDGSDLQGTPILDSVFGPLASFEEQIEVVPLPSRRLHRINAVAEDQIVIQDETPTG
                     DRTLSLVKAASPEPLVLLGSPGDYSISGDGSVLVVMESNRLWRFDLELAKQGAVSRSRI
                     DSGGLAKVIDRREEWHQLFRESWRLVRDFFHDEKRLRKIRWPSLYQKYEKRVQAVATRD
                     ELNQLLSELYAEVGSSHTRLSGGDIDQVDPVRVGLLGADLVYDATCGDYRLENFSRPGR
                     WLPEVAAPLIRAGVGEGSYLLAVDGVSLTRNREPWEVFQGKAGRQVHLLIRDPGGCDGQ
                     LREVEVVTLDMFEETTLRQLAWIEGNRAVVEAASAGVGRRLGYVYIPNTERRRGAGLWQ
                     GRHLFERQFRDQIDRDGLIFDTRFNGGGPLPYDIIDEIRRQPLDTLADRRGPLGSWPVP
                     NSTPHRVLLINGWSGSAGELLADFFKRADLGRLLGSRTFGGVNYYLGGPRLIDGGASSL
                     ANVVHLDPLSGETNRIEGKGVKPDLDVPEDLNQLAAGVDNQLQGAIEYLLSRLKR"
                     /tscore="-5.10"
                     /uscore="0.98"
     CDS             complement(10001..12361)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_43"
                     /conf="100.00"
                     /cscore="153.26"
                     /gc_cont="0.609"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_43"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 103.4;
                     E-value: 2.5e-31)"
                     /gene_kind="biosynthetic"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAG/GAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="5.20"
                     /score="164.45"
                     /score="164.4"
                     /sec_met_domain="LANC_like (E-value: 1.5e-21, bitscore:
                     68.8, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.2e-19, bitscore: 61.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 5.2e-08, bitscore: 25.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /source="Prodigal_v2.6.3"
                     /sscore="11.18"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MSSPPLFVWAPGVEIIAVQDLPPKLQDELQGHRHDFAVSARYTRQ
                     TTSLVDPPTVELLDEFREPSSIERAVQRYASRTGDRPSDVLEQAWSTLEVLLRRGLLLS
                     TKDPRMTAAPALVAGDSINDWTVIRPIRELEDTQIYLAKNPKNQLGVVKMRARASTPDR
                     EAIDNEARILESLEGSLAPRLLAVDNFGERPFLVSQWCPGIGVEQVASRWRLGHGRGGD
                     RRSLLRLAKAVAAAFGRLHEFGILHGDVHPQNVLVDAENRVWLVDFTLSSRIADGPVGQ
                     GGGISFYRAPEIARDLLAGKKTQADTLSEQFSIAALVYRLLTGHHYRDFDLEKETQLRQ
                     TAEAGMLPFRHRNLPDWPKIETILAKALDERPERRFETVRSFAKAFAAVSSRQLEESPP
                     GTAGALAKARSRILSSWGPQGAWWQEPLRSPMASVQNGAGGIALAASRIALLEEDSEIL
                     SIADLWIRRARRDLAAPEAFTSSELSVTSANIGHGSPQHNESGVHAVDSLIAHLGGQRQ
                     RQEASLRRYLESVNRPFLGLDVTLGTASQLVTGAILLETLHPGEIRDSLKDGGDRALTE
                     IWSGLSEEPIIHASSIDNLGLAHGWAGFLFATLRWREVSSGTWPPGFEDRLAQWAETAE
                     PLGRGLRWPWNLGHLRRQGSSMASMPGWCNGTAGHLLLACKIAGSGWTEFFSLAEKAAY
                     DVWDAGSTSASLCCGLVGRAYGLLAMYRLTGDAVWHHRATVLAETAASSGSFAEAPPYS
                     LFKGALSLAVLASDLDHAESAAFPFIEGDGWIL"
                     /tscore="4.69"
                     /uscore="-1.30"
     CDS             complement(12358..13554)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_44"
                     /conf="100.00"
                     /cscore="62.58"
                     /gc_cont="0.595"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_44"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGxAG"
                     /rbs_spacer="5-10bp"
                     /rscore="-0.49"
                     /score="67.25"
                     /score="67.3"
                     /source="Prodigal_v2.6.3"
                     /sscore="4.68"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MTESFLDRVLRPHVFRTSPSCELVVVDRLTAEEKRLWGDQLEGLS
                     SYGVLRSKAGGEARAIDRDLALLLFTLQLPGPLPTFLCREMEPKVLLRWIRGLLAAGIL
                     ELEMDGCFLNSEEALACFEDTQQEPAPMPTEPRLPARLKDISRAALVSASTLPDATSKK
                     RARWLYGYHRQPVTPYWRAKLQTQEQIQEWLGLNGEPGLRLDGLGKRLIERGWASWDFV
                     ERPRPGSEPTFKLYVSPRAKDLPVALAGLSEILGPLDAFHLKVGCDLPNILRADKLMLY
                     FATFEAMATAAERLQSRFGDLEPQGVPFTAEIGLEGLLSWGGDPPLSRHWSPEPTRRSW
                     RQWITERLAEAFDEVDSLGGSESFPAWRRVTDLLALEGINTETWSPDPLRWTGLENRQ"
                     /tscore="4.69"
                     /uscore="-0.55"
     CDS             complement(13577..13798)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_45"
                     /conf="97.73"
                     /cscore="3.21"
                     /gc_cont="0.550"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_45"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGA"
                     /rbs_spacer="5-10bp"
                     /rscore="6.23"
                     /score="16.37"
                     /score="16.4"
                     /source="Prodigal_v2.6.3"
                     /sscore="13.17"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MTKFRLKRLTINLDHRASSREENGDQVPTCPLSSNCITPTPRMNR
                     EERDEAVAVLEEALGNLRHQEELEDRVR"
                     /tscore="4.11"
                     /uscore="2.83"
     CDS             complement(13885..16095)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_46"
                     /conf="99.99"
                     /cscore="194.22"
                     /gc_cont="0.581"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_46"
                     /gene_functions="other (smcogs) SMCOG1272:TPR
                     repeat-containing protein (Score: 52.7; E-value: 6e-16)"
                     /gene_kind="other"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="9.19"
                     /score="198.22"
                     /score="198.2"
                     /source="Prodigal_v2.6.3"
                     /sscore="4.00"
                     /start_type="TTG"
                     /transl_table=11
                     /translation="LETERGSIIVGEWLVEPQLNRLRRGEEEVRIEPRSMEVLGILVRH
                     PKEVLSKAQILEAVWGDQVVSEESLTHAVWELRKALGDDARSPRYIQTIPKRGYRLIAA
                     VSPVEPEARPNSEPEATVLDFPEEPPRPEAPHRSWRSKVGWRTGGWLSVGVSLILALFL
                     SFENLWDQPSRQVMIRVVPSSCSNLCNDAEELAASIEDELAQRLRGLSGFPLLSRSTSE
                     DYLGASVKRIASRKVADYLVDVRVVETGNAESPLRVDLELVLAAEDRVLWRRSPPVNGV
                     EILTPVFSKLALDIAKVLLPLEPDAELDLQVFEDYLAILSLESSSVQATDGSPSGTMTP
                     AVHAYEKGLKNARLESFETDRLQKALELFEYAVKQDPQFHQAWIRIAKIRAKLCFNGFS
                     DREVLKSAYAAIDQAARHGAPEQEIQIAKAYYLYYGERDYSGALKVLREVHEKRPADTE
                     VLGLLAYLHRRFGNLKEASDLLREVLVFEPQNANVWSVLGETLHAQRRFQEAAESYQEA
                     LDIDPRNVISRGEAALNHFAMTGSAPAAQDILASHPHRQVDGLLLYSMPLLLYESRYQS
                     AKLLYSESVNTSDPLVRFQASWALIIAFRELGLEADARRQAEELCLFMEEKVRRNPGSK
                     FFGGYLALTYAFLGRKDEARREIDQALALAQGDEFSGPRIRELEAKVLALIGDESRSFQ
                     ILEELLEMQYQHCLTRNQLRRDPFWNPWREAFPPGLKETANG"
                     /tscore="-6.28"
                     /uscore="1.74"
     CDS             16259..17134
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_47"
                     /conf="100.00"
                     /cscore="52.52"
                     /gc_cont="0.588"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_47"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGAG/GAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="5.20"
                     /score="62.03"
                     /score="62.0"
                     /source="Prodigal_v2.6.3"
                     /sscore="9.52"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MKMNGGRVPVEAQRCESLPIAYGPSLEESPPRASHPRQLLEQHAD
                     WILRTAAKIARGKGIREADVADFAGWVVERLMSRNFNLLRACKQPERIRFYLGTVIRNL
                     AKDYCNHLWGKWRPSSLARRLGATAIDLERLCQRDGWQVREAIEILRSNHDCKVTAEEL
                     EDVASQLPSKPARTFVELDLEHMGQQLPFGERLLAREREVAQERISETLRSALSCLEAQ
                     DLEILRLHFEERRSLASISRTHQLDQRSLYSRRTRSLKRMRQVFQQEGLTWQEIAPALG
                     GESLGALEAG"
                     /tscore="4.69"
                     /uscore="-0.37"
     CDS             complement(17217..18800)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_48"
                     /conf="100.00"
                     /cscore="161.17"
                     /gc_cont="0.604"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_48"
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 321.9; E-value:
                     1.2e-97)"
                     /gene_kind="regulatory"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="GGA/GAG/AGG"
                     /rbs_spacer="5-10bp"
                     /rscore="-0.37"
                     /score="168.13"
                     /score="168.1"
                     /source="Prodigal_v2.6.3"
                     /sscore="6.96"
                     /start_type="ATG"
                     /transl_table=11
                     /translation="MSQEPVSQPPTPSRSILAIDDEVTALKGIRRTLRAHGHKQVLTCA
                     DGRQALDLMAKNPIALVLLDLVMPHINGEQILEEAGEKFPEVPVVVITAQHDVRTAVAC
                     MKLGAADYLLKPVAAEELISTVDQVLEQSALRYEARRLREDFFGETLREPKAFAQIITE
                     DPGMLRVFAYLEAISRGTQPVLISGETGTGKELLAQALHQVSLCEGPFMGVNVAGLDDA
                     MFSDTLFGHRAGAFTGAAGNRKGMIEKAEGGTLFLDEIGDLSEASQVKLLRLIQEREFY
                     PLGSDSPRPLRARVVAATHRAASALRQDLYFRLRSYRVRLPPLRQRLGDLPALVERFAK
                     AAAEDLGRPEPEVPPELFVHLSRYHFPGNVRELQAMVFDAVARQQTGQLPLQPFLESMA
                     EQPPPKDFASAGNGEENIDFPFPLPSMKQITQSAIQEALRRAQGSSSTAAEMLALSEID
                     DSKATVSIPGPTDRIIQRHQWKVLERQNILRALGQADWRIAGKDGAAELLGMRPSTLES
                     RIKALEIRKG"
                     /tscore="4.69"
                     /uscore="1.80"
     CDS             complement(18840..21056)
                     /ID="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_49"
                     /conf="99.99"
                     /cscore="217.28"
                     /gc_cont="0.607"
                     /gene="DHAR22-1_SAMN20209033_MAG_00000083-scaffold_26_49"
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 127.9; E-value: 1.1e-38)"
                     /gene_kind="regulatory"
                     /partial="00"
                     /phase="0"
                     /rbs_motif="AGGAGG"
                     /rbs_spacer="5-10bp"
                     /rscore="12.54"
                     /score="222.61"
                     /score="222.6"
                     /source="Prodigal_v2.6.3"
                     /sscore="5.34"
                     /start_type="GTG"
                     /transl_table=11
                     /translation="VPRKARKTLADDGSWKAAESRWGAATIVTVNSLLYFAGAAIGCWL
                     ADDPTNVASLWPANAILLVALLRTRPPLWPPIVAGCLVANAMATTLVSGAALGEAALLA
                     LPSLFTASSGIYLLRRFLPELIDLSTASQTLRFGLLAAVIAPLAGATVATILGSWIFQP
                     NSHWTFFYTWWGADALGILILSPVILTYRRRRLARLKGLGRLVEAGALIVAIAAASTLI
                     FGQSARPVAFLMIPLMLWAALRFGVFGCSVAGLLVSSLAVWFTSQGSGPFASMAATSID
                     QRILLMQVFLVVSIVLPLLLAVVVSERDQAERALRASEERYRAFVANSLEAIWRLELTE
                     PLPLHLTKQEQIDWLNRHAYTAECNDAFLELYGFESLEEFHHLTLEEFLVHGDPQNRQA
                     LAAAVESGYSGHSAESFVRRENGQLHTLLSSFTGVIENGHLIRVWGSSRDITEIKRIEA
                     ETERQRRELQEAEKMIALGTLVSSVAHEINNPTHFITLNTPLLRNAWRDALEVLDEQYR
                     RDPDFQLANLPYAEIRDEVGTIIEEISEGASRIKEIVAELRQRTREHDTPALSRLDVNS
                     VVASAVRLLEAPIQQATSDFTVDYGGHLPPVAGHGRRLEQVIINLILNACQALTETHQA
                     VQVTTRHDFAARRVVISIRDQGQGISPESLAQIRTPFFSTKKHQGGTGLGLAIASRIVK
                     EHRGELEFESTVGRGTTALVLLPLLSAPTGEISTFLETESTEDP"
                     /tscore="-5.10"
                     /uscore="-2.11"
ORIGIN
        1 tcgaggtgag acccttccgg ctgcgagaag agcacgattg gtcgccggac ctggaggaga
       61 tcagaggcct ggtttccgag cgtacccgag ccatcgtaat ctgtaatccc aacaacccta
      121 cgggggcggt cctatctcgc caggacatgg agggaatcgt cgagatcgct cggcaagggg
      181 atgccctcgt ctatgcagat gaggtctata agggagccga gttcgacggg caggaagggc
      241 cgagttttcg ggatctggat gagcgttgca tcgtcgccgc aggactgtcc aaggctttgg
      301 ctcatcccgg gctgcggatc ggctggctgg ttgggccgga agagttcatt gaagaggcct
      361 ggctgcgcaa cgactacacg acgatcacca ccggcttgct caatgagacc gtcgccacgg
      421 tgatcctgca accggagcgt cgccaacaga ttctccggcg caaccgggag atgctccagg
      481 gcaatctcaa aatcctccag gattggatct cccaacgccc ggggctcttc gacttcattc
      541 caccgaaggc tggtggaatg tgcttcctgc gctaccacca tcccatcggc tccacggagc
      601 tggcgacgaa actgcgggac gaaaagagac ttctagtcct tcccggggat gtctatggga
      661 tggaccacta catccgcctc ggtatcggtg agcgcccgga ttatctgcga gcgggattgg
      721 agttgcttgg gaagggtttc gacgagctca cgtagtggtg ctaggtgcgc ggatcgcacg
      781 ccacctcgcc gcgtgctcgt ctctcggctt gtgcgccgta cagacgtacg gctccgcgcc
      841 tcgctcctgc gctgcgacga tttggcgcac gcttcacgca cctgggagtt gggagttggg
      901 agttgggagt tgggctatgg atctttgtag acgatgccgc ccttcatgac gaattcgata
      961 ttttctagga ggctgacgtc ttccagggga tttcccgtca cggctaccag atcggcttcg
     1021 aagccggcgg cgagttggcc gactcgatct tcaattccca agagctcggc agcgttggtc
     1081 gtggcggttc gaatggcttc caggggagtc atgccgaagc gcaccatgcg agaaaactgc
     1141 ctcccattgt ccccgtgggg atagaccgcg ctatcggtgc cgaaggccat gcggacgccc
     1201 gcttggtgcg ctcgggtgaa gttttctcgt tgaatggtgc ccacttcccg ttccttgtcc
     1261 agggactctt cgaggacgcc gttcttcttg ccttccgtga ggatgtgctc ggtgacgtag
     1321 acatccatga caaagaaagt gcccctttcc ttcgccaggg caatggactc gtcattgacg
     1381 aagctggcgt gttcgatgga gtcggccccg gcgaggatgg cgttctgaat gcccgcagct
     1441 ccatgagcat ggacagcgac ccttcgacca tgggcgtggg cttcctcaac caaagcggtc
     1501 aattcttcga gagtgtattg ggtggcgtcg agtttggtcc ctttggacag caccccaccg
     1561 gtggagcagg tcttgatgag atcgacaccg aatttgacgt tctgccgcac ccggcgtcga
     1621 atttcccagg ggccgtcagc gaccccggtt cctaccgagc catactcatg agggagcagg
     1681 ttgttatcac tgcaatggcc cccggtgatg ccgatgggcg gccccgaaac aagcagccta
     1741 ggccccagga tctcccgctt cgcgatggcg tcccgcaggg cgacgtcacc gtaacccggg
     1801 gcgccgacca tgcggacggt cgtgaagccg gcttgaaggg ttttcgctgc attcttgacg
     1861 ccgttgagag tcgcttccgg aagggacacc gtcaggcccc gcaggccttg gtcgtcagag
     1921 tcgctcatca agtgggtgtg gcagtcgatg agcccgggca ggacggtctg tttcgataga
     1981 tcgatgacct tcgcctccgc cggcagcttc ctagacgagg cggcttcgac ggcgacaatg
     2041 cggccatcct ggatggtgat cacttggtca cggagcagct gccccgcttc cacatccagc
     2101 accgccccgg ctttcacata ggagagttgg gcggcgctgg gggcagaaac agcgagtccg
     2161 gcgacggcag cgatcgcgaa gaggctcgtt cgagtccaca tgttttttgt ctccttagaa
     2221 ggtccgtcga ggatagcaaa tcaaccccag ggccaacgaa ggaagaaggc cctccccctc
     2281 tgcaccccaa gatcgagagg aaccctaggg aatggggaag ggaccggagc ggcattaggt
     2341 cagggttgag tcgccagagc tcccgagtcc caaacgatct ctccacccac cacggtgagc
     2401 aagctgacgg tctctggaat cgccggggga ggaatctcga agatgtcttg ggacaacact
     2461 gccagatccg ccaggcgccc tcggcgcagg ctacccttgc gcttttcttg gaattcggcg
     2521 gtcgccgagc cgagagtgta ggcggtgacg gcctctgcca cggtcagagc ctcttctggg
     2581 tgaaaggggt gaaagacggc gaggaagatg tccacaaagg ggttggggaa agcgccgtca
     2641 gaggccaagg ccaaggagac tccattgtcg agcagagtct tcaagggttg agcggcggcg
     2701 gctcgctcgg ggcccaaggc gggggccaga tcaagggcta gatgggtcgg gttctgcacc
     2761 acgatcaatc ccaagcgacg ggcccgggcg agatgatcct gctggaggag gtctccgtgt
     2821 tccaaacgaa ctcgccgccg acgccaaacg ggcgccggcg caacggattc catggcgctc
     2881 aaggcttggt cgatggctcg gtcaccgacc gtgtggaaga ggatagggtt gcgggctggt
     2941 ggctccgcca ggctgcggcg cagggaacgg atcagatttc cggtcggaat gttgagcacg
     3001 ccgtctccgg ggaaatccgc gtagggttcc cgcagagcag cactgcgctc gacgggagtg
     3061 ccgtccagaa gccacttgat gccggaagat cggaccttcc tcaaggggtg gcgttggcga
     3121 gaccggcagg actcctgcgg ggtcaaggga acacacatgg accggactcg aacggccatg
     3181 tccgcctcgg cgagaacgcg ttcactgcgc tctcgggtca gacccaccgt catctcctga
     3241 atcgaggtga tccccaattg ggtcaataga ggggagaagg cttcgaattg ggcgatcatc
     3301 agctcatccg gcgcttgggc ccggatctca cgaaaaattc gaaacaggcc gtactcgttg
     3361 gcgaccccat tgagaacgtc ggtgccggga aagcggccat aggtgccgcc gaaggggtcc
     3421 gcttctgttt cggtgagtcc tagggtctcg atccccaggc tattgaccac accggtgtgg
     3481 ctcgaccagg taaacaggag aaccgggttg tccggagcga cggagtccaa agcaacacgg
     3541 ttggtatcgg gatcgaacag ggccgcctcg ccaatggtga cgacgatcca ctcaccgggt
     3601 tcggcaatgg ccaccgctcc ggcaacctgg gcgagggcct cgttcagagt tgggccaggg
     3661 cctggaatgt tgatgggagg gagggtcagc cggggcaaac cgacggcgag gtgagtgtgc
     3721 gcgtcattga agccgggcac cactaacctt ccctggaggt cgagggaaag ggtgttgggc
     3781 ccctccaagg ctcgcacttc tgcgtcgcta cccacggcga ggactctcga tccgcgaata
     3841 gctaccgctt ccgcccaggg cccctgagta tctgctgtga agactttgcc tccatgaaga
     3901 acaacgtcgg ctctcgggga tgcctgagcg gcgccgatgg agaaggaaat gagcgcaaga
     3961 aaagagatga aggtccactt atgcattctg agaactcctt tgctatgtaa atacgcgaat
     4021 gaactctagc atgaggggca ggacctggag gctgggaggg agaattcctg ctctgtcaca
     4081 gcttcactgc tgcctcgtct gcgaagcgat tcgggaggcc gaggggggcc actcacctat
     4141 tgggaatctc gcagtcgtcg gtttcggaaa cggaaggcac ggagccacta cctccggatc
     4201 gtgttcacgg aagttctttg ttcgacccct tgattcccac aggttctctc ctgcgacgac
     4261 gaatccaacg gtgtctgagt tctcgttccc ttcgtggttt ttccgggtga agtctttcta
     4321 gattgcctca cgacgaatcg gaaaagagtc cggtgcaaga gaatcggtga atccgtaaag
     4381 agtcgagatg gtggggggca gagtctcgac ttcctgactc ctgaactaga gaagaggccg
     4441 acattgggtc ccctcgatat tgatgctgaa acccatttcg tttcagcagt tttttggagt
     4501 cacgtaagga gagagtgtta tgcgttttaa tctagcaatt ctattgggtt tagtcgtttt
     4561 ctgtttcgga gctcaggccg atagcatttc tgtggagacg tctccggcgc cggccgaagc
     4621 tgctgttcag caagatgctt ccactctgtt ttttcaaacg cccacttttc tcgatgacgc
     4681 agatgctgtg gaagcctgtc cggatgtcga tgctgatggt gaaggagccc ctgtgccgat
     4741 catctgcaac tgcctatgca acggtgttgc tgtggccgtc aatctcgctt gtcggcatgg
     4801 cgagacttgt aacgatgtga atggccgacc ttgcaatacg ggagctggct ggtctactta
     4861 taacggctgc tagaaccgcc gctcaccagg agctctcttt ggaatctttc cgagggggct
     4921 cctgctttcg ctgcgaatat ttagtggcta ctttgttacc agttttctag gctccattcc
     4981 aaaggagtat ggcttgactc tttcaaccct tgaagcgccc agctcggggc cttcgaattc
     5041 tgtcccatga agagccttca ggctactttt cgatccggtc gggccatcgc cgggcataga
     5101 gcctgagttc ctcctcgtcc cctggttgcc ggactggttt ttcgaaccgt aggccgagtt
     5161 tttccaagag ccggatcgag gatcgattct cttccaaagt aatggctaga acgaggggga
     5221 aggcgtgggt ctcctcagac cagtcgatca ctgctttagc cgcttcatag gcatagccct
     5281 ttccccaaaa gcgaggcagg aaggcaaaac cgatgtccgg agcgtccaag gtgggtcgcc
     5341 ggagaagccc gcagaggccg atgggaattc ccgattcagg gagctcggtg aggaacagcc
     5401 ccaggccgaa ttgagcatag ctagccatgg ggccttctcg gagataccgc cgggcgtcgt
     5461 ccagggtgtg aatgccacgg tcgccgatga aacgaatcca agaagggtca ttgaccaact
     5521 ccagggcaaa aggggcatcc gccagggtca gctcccgaag gcgcaggcgt tcggtttcca
     5581 ggggaaggtg ttcgagggcc tgatgaacgt tgggatggcc aggggtggaa ttttccatgg
     5641 gcctaagcct atcgcttgtt ccctcagcag tcttggggtc agaggagttc ttgaatctgc
     5701 aaggagctcg ttgggctaaa tttctgaaac tgaacgaagg tcagcggact tgttgcctcg
     5761 ccttacttcc gaggtccgac tttggcggta cccagggggg aagaccctgg ctcctcttcc
     5821 tccaagggcg agcagtgagc cttcagcatg atgacggaca gcacctcgac gggtgagctc
     5881 agggccacgt cctcgcggta tagctcacgg ccgctggaag taacggcttt ccgcaagact
     5941 ccaggttccg ttcgttggcg gccctcggaa tcccggtagg tgattttgta ttcaccatag
     6001 accactgcgg gtggagaggt gagcaattcg atgcggaacc gagtcgaaaa gtgctcgccg
     6061 atgatcctgg gcatataagg cgagatgcgg acctggcatt cgagctcttg aggactgctg
     6121 cctgaggggt gggtgtccgg gagaccgaag cgagcttcga gagcggtgaa cactaccgac
     6181 cctgctagca ccaggagggc cactaggagg gtgacggtca ctgggtgtcc tggtttctcg
     6241 ccaacttcat taggtttcgc tggcaacatg gagggcatct tggtctcctt ctagaatctc
     6301 gaagtgaatc catctccgac accgagccga tctcttgcgg cgactccgta acctgagaga
     6361 cctgggttct gagagatccg tgtgctgaga gatccgcggc atgtgtgctc cgtttcacga
     6421 gtcttccgct aacccgtggc cttgcctccg agagctttct ggaaccctcg gctgatcctt
     6481 tcctttccaa gcagggacgg ccatccccgg cggccctgac ttctcttcaa gagagggact
     6541 ggaattcaga tttgtcggct agtaagaggg aaatttcacc ttgcgtccct cttacttctg
     6601 tgaaatagct acatttcgca ccaaggaggg attgctgtga gccagctcca agaaggcctg
     6661 ccgggaatat ttaggcagcc ggatgtttcc gagagtcata tcgtctttgt ctatgccagt
     6721 gatatctggc gggtcgagaa acagggaggc cccgctcagc gtttgacctc agttcaggga
     6781 acggaatcct tcccacggtt ttcaccgggg ggagagtcgc tggccttcag tgccgattac
     6841 accggcaacc gagatctcta caccctttcc accgctgggg gagtgcccca gcggaagact
     6901 tttcatcctg cttcggattt gctgatcgat tggcatccgg aaggccggaa gctactgttt
     6961 gcctcgaggc gtcaaattca caacagcttc tattctcatt ttttcgagat tcccatcgag
     7021 ggaggtccgg cgactcggat caagattccc ttcgcagcgg atggggccta ctcgcgctcg
     7081 agcaagctcc caggaagatt tatcgctttt cagatgctcg gtcgggacgt caccttgtgg
     7141 agggggtacc aaggggggct cgcctcgggc ctattcgttt tcgataccct gacccatcga
     7201 gtggtgcgtc tggcttatcc gaaccgcacc tacgctgccc ccatgtggcg cgatggagat
     7261 ctctatttca tttccgatcg cacagatcaa cctttgaaag aggggaagcg gaatcggaag
     7321 aggatcttca atctttgggt ctttcgaggt ctcgagactc aattggaaaa ggagctggag
     7381 gaaaagcaga tcgagagtcc ggagcgattg acccaagaaa acgaagatct caactttccc
     7441 gccatggggc cttcagacat ggtgttcact cagggtgggg aagtctttcg aattcccttc
     7501 ggtgacggca caccggactt tgggaatccg ctgagagtgc ctatcgagct cacgcctgat
     7561 cgctcggctt tggtgcccga gtggaggccg gtcgataacc tgattcaatc tttcgatctc
     7621 tcgtcggatg gatcccgcct cctggtcagc gcccgaggtt ctattttcga cctgcccgta
     7681 gcgggcggtc ctactcggct tctcgatcgc tttgggccag gatcggtccg cctcgagtcc
     7741 gccgaacgga gcgcggtctg gctggacgag gagcacattc tctttcacag tgatgcccgg
     7801 cccacccaga aagacccatc cgtagcacag gcaagctctg gacgaagcaa gcctagtgag
     7861 tacgacctag tgcttcacca gatcgcctcg ggcaacgaaa aggtgtttca tttcaaggag
     7921 ggctttcgct atcggctcac cgtgtccccc tgctgccacc gggctgtttt cgtcgaccag
     7981 accagcagct tgcaattggt ggagctggac acccacgatc gcttggtcac tcgagagatt
     8041 ggcaagctcg agggaatgct gccgtaccaa ttgcagcgca tgcgtccttg ctggtcaccg
     8101 acgggtcaca ttgtggtttt tcatgattat gcaccgaacg gcaatcgacg tttgaacgca
     8161 gtggtggtag acagtgccga gaggcgcatc ctcacttcgg gttttacttc cgactgcaag
     8221 ccgagcttcg cccctgaggg cacctacctt tattttgttt ctcgccgagg ccttcatctc
     8281 accgaaagcg agctgggtgg cggtgcggct gcctattcaa atacggatcg gttggctcga
     8341 gtccaggtca acctggcggc taccagcggt tcgcgggatg gctctgatct ccagggtaca
     8401 cctattctcg acagtgtgtt tggccccttg gcgtccttcg aagagcagat cgaggtggtg
     8461 ccgttgccct ctcggcgatt gcatcgcatc aacgccgtcg ccgaggatca aatcgtgatt
     8521 caagacgaga ccccgacggg agatcgtacc ctttccttgg tcaaggcggc ctctccggag
     8581 cctctcgtgc tcctgggcag ccccggagat tattctattt ctggtgatgg atcggtgttg
     8641 gtcgtcatgg aaagcaaccg gctctggcga ttcgatctag agttggccaa gcaaggcgca
     8701 gtttcccgct cgcgtatcga cagcggcggc ttggccaaag tcatcgaccg gcgagaggaa
     8761 tggcatcaac tattccggga gagttggagg ttggtacggg acttttttca cgacgagaaa
     8821 cgactccgga aaattcgttg gcccagtctc taccaaaagt acgagaagcg agttcaggca
     8881 gtagcgaccc gtgacgagtt gaatcagctt ctcagcgagc tctacgccga ggtgggctct
     8941 tctcacactc gcctttccgg tggagacatc gaccaagtgg atccggttcg agtcggattg
     9001 ctcggtgcgg acctggttta cgacgcaacc tgcggtgatt atcgtttgga gaacttctcg
     9061 aggccgggcc ggtggctacc ggaagtggcg gctccgttga tcagagccgg tgttggagaa
     9121 ggcagctatc tgttggcggt cgatggggtt tcattgacca ggaaccggga accctgggag
     9181 gttttccagg gcaaggcggg gcggcaagtc catttgctga tccgggaccc gggaggttgc
     9241 gatggacaac tgagagaagt ggaagttgtc accttggata tgttcgagga aaccactctt
     9301 cggcagctcg cttggatcga ggggaatcgc gccgtggtcg aggcggcatc ggcgggagtc
     9361 ggacgtcggc tgggatacgt ctacatcccc aacacggaga ggcgcagagg tgccggcctg
     9421 tggcaaggtc ggcacctttt cgaacgccag ttccgagacc aaatcgatcg agacggcctc
     9481 atcttcgaca ctcgattcaa cggcggtggg ccgctgccct acgacatcat cgatgaaatc
     9541 cggcgccagc ccctcgatac cttagcggac cggcgtggtc ctctaggtag ttggccggtt
     9601 ccgaactcga ccccccatcg agtcctcctc atcaacggct ggtccggatc ggccggcgag
     9661 ctgttggcag atttctttaa acgcgctgat ctcggccgcc tgctcggcag tcggaccttc
     9721 ggcggcgtca actactacct gggcgggccg agattgatcg atggtggggc atcttccctg
     9781 gccaatgtag ttcatctcga tcctctatca ggggaaacca atcgaatcga aggaaaggga
     9841 gttaagccgg acctcgatgt tccagaagat ctcaaccagt tggcggcagg tgtagacaat
     9901 cagctccagg gagcgatcga gtacctgctt tcccggctga agagataggg agaggggctt
     9961 tcgtcgggaa ccgagacaca tcctggactc aatcgaacga ctagagaatc caaccatctc
    10021 cttcgatgaa gggaaaagca gccgactctg catggtcgag atcactcgcc agaacggcta
    10081 gtgatagggc acccttgaaa aggctgtagg ggggcgcttc ggcgaagcta ccgctgctgg
    10141 cagcagtctc ggcgagaacg gttgcccggt gatgccaaac agcatcccca gtcaggcggt
    10201 acatggcgag caaaccgtag gctcgaccaa ccaatccaca acacaggctc gcagaggtgc
    10261 tgcccgcatc ccatacatcg taggcggcct tttcggcgag ggaaaagaac tcggtccagc
    10321 cgcttccagc tatcttgcaa gctagcaaga gatgcccagc ggtgccattg caccagccag
    10381 gcatcgacgc catggaggat ccctgacgtc tcagatgccc aagattccat ggccaccgca
    10441 accctcgacc taggggttcg gccgtttcgg cccactgggc caggcggtct tcgaagcctg
    10501 gaggccaagt tcccgaggag acctctctcc agcgaagggt ggcgaatagg aagccagccc
    10561 atccatgagc aagtccgaga ttgtcgattg aggaggcatg gatgatgggt tcctcggata
    10621 agccactcca aatctcagtc agggcacggt ctccaccgtc cttcaaggag tctcggatct
    10681 cgcctgggtg aagggtctcc agcaagatgg ctcctgttac cagttggctt gcggtgccaa
    10741 gggtgacatc gaggcccaga aacggccggt tcacggactc gagatatctc ctcaatgagg
    10801 cttcctgacg ctgccgttga ccccctaggt gggcgatcag gctatcgaca gcgtgaacac
    10861 cactctcgtt atgctgcgga gaaccatgac cgatgttggc tgaggtaacg ctgagctcag
    10921 aagaggtgaa ggcctccggg gcggctaagt cccgccgggc acgccggatc cacagatcgg
    10981 cgatggagag aatctcgctg tcctcttcaa ggagagcaat tcgagaggct gcgagggcaa
    11041 tgccaccggc gccgttttgc accgaggcca tggggctgcg cagcggttcc tgccaccagg
    11101 caccttgcgg cccccaggag gacaagatac gagacctagc tttggccagt gctccagccg
    11161 ttcccggcgg gctttcttcc agctgcctcg aggagacggc tgcgaaggct ttggcaaagg
    11221 accggacggt ctcgaagcgt cgctccggtc gctcgtcgag ggctttggcc agaatcgtct
    11281 cgatctttgg ccagtccggc aggtttcgat gtcggaaggg caacatgcca gcttcggcgg
    11341 tctggcgcag ctgcgtctcc ttctcgaggt caaagtctcg atagtggtga ccggtgagca
    11401 ggcggtagac tagcgcagcg atcgagaatt gctcactgag ggtatccgcc tgggtttttt
    11461 tcccggcaag gaggtcgcgg gcgatctcgg gagccctata gaaggagatg ccaccgccct
    11521 gccccacggg cccatctgcg attcggctgg acagggtgaa gtccactagc caaacgcgat
    11581 tctctgcgtc cacgaggacg ttctgagggt ggacgtcgcc gtgcaggatg ccgaactcat
    11641 gaagccgccc gaaggcggct gcgacggcct ttgctaaacg cagcagggat ctacggtctc
    11701 cgcctcttcc atgaccgagg cgccaccgac tcgctacttg ttcaacaccg attccggggc
    11761 accactggct caccagaaaa gggcgctcgc cgaagttgtc aacagctagg agacgagggg
    11821 ctaggctccc ttctaggctc tccaggattc gcgcctcgtt gtcgatcgct tctcggtcgg
    11881 gagtcgacgc tctggcccgc atcttgacca ctccgagttg attcttgggg ttctttgcca
    11941 agtagatctg ggtatcttcc aactcgcgaa tcggacgaat gacggtccaa tcgttgatcg
    12001 agtctcccgc taccagagcc ggcgctgccg tcatcctggg gtctttggta ctcagcaaca
    12061 atccccgccg caaaagcact tcgagagtgg accaagcttg ctcgagtaca tcggacggcc
    12121 ggtcgccggt ccgggaggcg tagcgctgga cagctcgttc tatggaagag ggttcacgga
    12181 actcgtccag gagctcaacg gtgggcgggt cgaccaggct ggtggtttgt cgcgtatagc
    12241 gggccgagac ggcaaagtcg tgacggtggc cttgaagctc atcctggagc ttcggcggca
    12301 ggtcctgtac ggcaatgatc tcgacgcctg gggcccagac gaaaaggggt ggcgagctca
    12361 ttggcgattc tccaggcctg tccaacgcag gggatccggt gaccaagttt ccgtgttgat
    12421 tccttctaag gccagtaggt cggtgacccg ccgccatgca ggaaaggact cggatccacc
    12481 aaggctatcg acttcgtcaa aggcttctgc cagccgctcc gtgatccatt gacgccagct
    12541 gcgccgtgtt ggctctgggc tccaatgacg gcttaggggc gggtcgcctc cccaggaaag
    12601 tagaccttca aggccgatct cggcggtgaa aggtactcct tggggctcta ggtctccaaa
    12661 gcgactctgc agccgctccg cagcggtcgc catggcttcg aaggtggcga aatagagcat
    12721 caacttgtcg gcccgcagaa tgtttgggag atcgcagcct actttcaggt ggaaggcgtc
    12781 gaggggaccg aggatctcgg agaggcctgc caaggctacg gggagatctt tggcccgagg
    12841 gctcacgtag agtttgaagg tcggttctga accaggcctt ggtcgttcta cgaaatccca
    12901 agaggcccag cctctttcga tgagtcgctt gccgagaccg tccagacgga gtcctggttc
    12961 gccgttgagg ccaagccatt cctgaatctg ttcctgggtt tgcagcttgg cgcgccaata
    13021 aggggtgacg ggttggcggt ggtagccgta gagccatcga gcgcgtttct tggaggtggc
    13081 atccggtaac gtcgatgcac tgaccaaggc ggctcgggag atgtccttga gacgagcagg
    13141 aagtcttggc tcggttggca tcggtgctgg ctcctgttgt gtgtcctcga agcaagctag
    13201 ggcctcttcc gagttgagga agcatccgtc catttctagt tcgaggatgc cagcggcaag
    13261 gagcccacga atccaccgga gcaatacctt cggttccatc tctcgacaga gaaacgtagg
    13321 tagaggcccc ggcagttgga gggtaaacag aagcaaagcc aagtcgcgat cgatggcccg
    13381 tgcttcgcca ccggccttgg accgcaagac gccgtaggag ctgagacctt cgagttgatc
    13441 tccccaaagg cgtttctctt cagcggtaag acggtcgacg accacgagct cgcagctcgg
    13501 gctggtccgg aaaacgtggg gccggagaac gcgatcgaga aaggactcag tcatatcatt
    13561 cttctgaggc tgaaaactac cggaccctat cctctaactc ttcctggtgt ctgaggtttc
    13621 ccaaggcttc ctcgagaacc gcgaccgctt cgtccctttc ttcccgattc attctcggag
    13681 tgggcgtgat gcaattggat gacaagggac aggtgggtac ctgatccccg ttttcctctc
    13741 gggaggatgc ccgatggtcg agattgatag tgagtctctt gagccggaac ttcgtcatgg
    13801 cacttttcct ttttagaact gatttgtggg aagggttgcg actgcctgcc tagggggacg
    13861 catcgatcag atttaccgat ttcctcaacc gttagcagtt tccttcaggc ctgggggaaa
    13921 cgcttctctc caggggttcc agaaagggtc acgccgcagt tggttcctgg tcaagcagtg
    13981 ctggtattgc atctcgagca gctcctccaa gatctggaag ctgcggcttt cgtcaccgat
    14041 cagggcgagg actttggcct ccagttctcg gattctcggg ccagagaatt catctccctg
    14101 agccaaggcg agggcctggt cgatttcacg gcgagcttcg tcttttctac cgaggaaggc
    14161 gtaggtgagg gcgaggtagc caccgaagaa cttggatcct gggtttcgtc tgaccttctc
    14221 ttccataaac aggcagagtt cctctgcctg gcgtctggca tcggcctcca atcccagctc
    14281 ccggaaggcg atgatgaggg cccaagacgc ctgaaagcgg actagcggat cggaggtgtt
    14341 gacactttcc gagtagagaa gcttggcact ttggtagcga ctctcataga gcagcagcgg
    14401 catcgaatag agcagcagac cgtctacttg gcggtgagga tggctggcga gaatatcttg
    14461 agctgccggt gccgaaccgg tcatggcgaa gtggttgaga gccgcttcac cccgggagat
    14521 gacgtttcta gggtctatgt cgagggcttc ttggtaagac tcagcagctt cttgaaagcg
    14581 ccgctgagca tggagagtct ctcctaggac ggaccaaacg ttggcgttct ggggttcaaa
    14641 gacaaggacc tcacgaagta ggtcgctggc ttctttcagg ttgccgaacc ggcgatggag
    14701 ataggcaagc agcccgagca cctcggtgtc cgcaggtcgt ttttcgtgca cttcccgcaa
    14761 gactttcagg gccccgctat agtcccgttc cccatagtag aggtagtagg ctttggcgat
    14821 ctgaatttcc tgctctggag caccgtgacg ggcggcttga tcgatagctg cataggcaga
    14881 tttcaggacc tcccggtcgg aaaatccgtt gaagcatagt ttcgctcgga tcttggcgat
    14941 acgaatccaa gcctgatgga attgtgggtc ctgtttgacc gcgtattcga agagctccaa
    15001 ggccttctga aggcgatccg tttcaaagct ctccaggcgg gcatttttca agcccttctc
    15061 ataagcatga accgccggtg tcatcgttcc actgggggac ccgtcagtgg cttgaaccga
    15121 agaactttcc aagctgagga tagccagata atcctcgaag acttgaaggt cgagttcggc
    15181 atccggttct agggggagca ggaccttggc gatgtcgaga gccagcttag agaacacggg
    15241 agtcaggatt tcgaccccgt tcactggtgg gctccgtcgc caaagaactc ggtcctctgc
    15301 tgctagcacc agctctaggt ccacccgcaa gggagattcc gcattgccgg tctccactac
    15361 ccgcacatct accaaatagt cggccacctt ccgggacgcg atgcgcttca ccgatgcacc
    15421 tagatagtcc tcagatgtgc tgcgggaaag aagagggaat ccactcagcc ccctgagccg
    15481 ctgtgccagc tcgtcttcga tggaggccgc gagctcttcc gcatcattac agaggttcga
    15541 acaggaggaa ggaacgacgc ggatcatcac ttggcgactc ggttggtccc agaggttttc
    15601 gaaactcagg aagagcgcca ggatcaggga taccccaacg ctcagccagc caccggttcg
    15661 ccatccgacc ttggacctcc aggaacgatg aggagcttct ggccgggggg gctcttccgg
    15721 gaaatctaga accgtagctt ccggctcaga attgggtcga gcttcgggct cgactgggct
    15781 gaccgccgca atcaaccggt agccgcgttt cgggatggtc tggatatacc gcgggctacg
    15841 ggcgtcatcg ccgagggctt tgcgcagctc ccacactgcg tgggtgaggg attcttcgga
    15901 gacgacctgg tctccccata ccgcttcgag aatctgtgcc ttggagagga cctctttggg
    15961 gtggcgcacc aggatcccta ggacctccat ggatcggggc tcgatgcgca cctcttcttc
    16021 tccccgccga agccgattca gctgcggctc gacaagccat tccccgacga tgatggaccc
    16081 tcgctcggtc tccaaagaca atcctccctg ctctttttaa aacgcaggat atcgcgatct
    16141 caagatttcc tcatgctttc tagaggcagt cttcatgact ccaatcttct gagacggcag
    16201 gttgggccgg cacccaaaac tcgaagcagc ccgatgtcac ggacgattgg agaagaaaat
    16261 gaaaatgaat ggtggaagag taccggttga ggcccaacga tgcgaatccc tgccgatagc
    16321 ctacgggccc tctttggaag aatcacctcc cagggcatcc catccacgcc agctcctgga
    16381 gcagcacgca gattggattc tccggacggc tgcgaagatc gctcggggga agggcattcg
    16441 agaggcggat gtggcggact ttgccggctg ggtggtcgaa cgtttgatga gccggaattt
    16501 caacctcctc cgagcctgca aacaaccgga gaggattcgc ttctacctag gaacagtgat
    16561 ccgcaaccta gcgaaagatt attgcaacca cttgtgggga aagtggcgcc cctcctctct
    16621 ggctcgacgc ctcggcgcta cggccatcga tctcgagcgt ctctgccagc gagatggatg
    16681 gcaagtgaga gaagctatcg aaatcctgcg ctcgaatcac gactgcaaag tgactgcgga
    16741 ggagctggag gacgtggcga gccaattgcc gtctaagcct gccagaacct tcgtggagct
    16801 cgatctggaa cacatggggc agcagctccc ctttggagag cgacttctgg ctcgggagcg
    16861 agaggtcgct caggagcgga tctcggagac cctgcgttca gctctgtcct gcctggaggc
    16921 ccaggatctg gaaatcctgc ggcttcattt cgaagaacga cgtagtctcg cctccatctc
    16981 ccgaacccac caattggatc agcgatcctt gtattcccgg cgaactcgca gcctgaaacg
    17041 aatgcgccag gtttttcagc aggaaggact gacttggcag gagatcgctc cggctctcgg
    17101 tggcgagtcc ttgggagcct tggaagccgg ctgaggtcag gctgggatca gactgtgacg
    17161 aaggggaatc gatagctgga aagctcggtg taggtccgcg ggagaaccgg gctggctcat
    17221 cccttgcgga tctctagagc tttgatgcga gactccagag tcgaaggccg cataccgagc
    17281 agctcggcgg cgccgtcttt gcccgcgatt cgccagtcgg cttgcccaag ggctcgaaga
    17341 atattctgcc gttccagaac tttccattga tgtcgttgaa tgatgcgatc ggtggggccg
    17401 gggatcgaaa cagtagcctt ggagtcgtcg atttcgctca aggcgagcat ttcggcggcg
    17461 gtggaggagc tgccctgagc tcttctcagg gcctcttgga tggcggattg ggtgatctgt
    17521 ttcatggatg gtagcgggaa ggggaagtcg atgttttctt caccgtttcc tgcactggca
    17581 aagtccttcg gcgggggctg ttccgccatg gactcaagga agggctggag aggtagttgt
    17641 ccggtctgtt gccgggccac agcatcgaag accatggctt ggagctcccg cacattgccc
    17701 gggaaatggt accgggaaag atggacgaat agctcggggg gcacttccgg ctccggccga
    17761 ccgagatctt ccgcagcggc tttggcgaac ctttccacca gggctggtag gtcgccgagg
    17821 cgttggcgca acggtggcag tcgcacccgg taggaacgga ggcggaaata caggtcttgc
    17881 cgcagagcgg aggcagcgcg gtgagttgcc gcaaccaccc gggctcgcaa gggccgcggt
    17941 gagtccgagc cgaggggata gaactctcgc tcttggatca agcgcaagag tttgacctgg
    18001 gaagcctcgg atagatcgcc gatctcatct aggaaaaggg ttcccccttc ggctttttcg
    18061 atcatccctt tgcggttccc ggcggcaccg gtaaaggcac cggcacggtg tccgaacaag
    18121 gtgtcggaga acatggcgtc gtccaggcca gcgacgttga cacccatgaa ggggccctca
    18181 cacaagctga cctggtgcag ggcttgggcc aacaactcct taccggtgcc cgtttcaccg
    18241 gaaatcagta ccggctgggt gccccgggaa atggcttcca agtaggcgaa gacccgtaac
    18301 attccaggat cctcggtaat gatctgcgca aaggccttgg gttccctcaa ggtctctcca
    18361 aagaagtcct cccgcaaccg tctggcctcg tagcgtaggg cactctgttc caagacctgg
    18421 tcgacggtgg agatgagctc ctccgctgcc accggtttga ggagatagtc ggcggcgccc
    18481 aatttcatgc aagcaacggc ggtgcgcacg tcgtgttgcg ccgtgatcac caccacggga
    18541 acttcgggga acttctcccc cgcctcctcg agaatttgtt ctccgttgat atggggcatg
    18601 acgaggtcga ggagcaccaa ggcaatgggg ttcttcgcca tcaggtcgag agcctggcgg
    18661 ccatcggcac aggtcagcac ctgtttatga ccatgggccc tcaaggtgcg gcggattcct
    18721 ttgagggcgg tcacctcgtc atcgatggca agaatcgacc gacttggagt gggtggctgg
    18781 ctcacgggtt cttggctcat gttttctggc tcatgttttc tggctcgtag gtttctggtt
    18841 cacgggtctt cagttgattc agtctccaga aacgtcgaga tttcccccgt cggtgccgac
    18901 agcagtggca ggagcaccaa agctgtggtg cctcgaccca cagtggattc gaattccagc
    18961 tcaccgcggt gctctttgac gatccgtgag gcgatggcga ggcccaggcc agtgcctcct
    19021 tggtgtttct tggtggagaa gaagggagtg cgaatctggg cgagactttc cggggagatg
    19081 ccttggcctt gatctcgtat cgagatcacc acgcggcgag ctgcgaagtc gtgacgggtc
    19141 gtgacctgta ccgcctgatg ggtctccgtc agcgcttggc aggcattgag gatcagattg
    19201 atgatcacct gctccaaacg cctcccgtgg cctgcaaccg gcggtaagtg gcctccatag
    19261 tccaccgtga agtcgctggt ggcttgctgg ataggagcct ccaggaggcg caccgcggag
    19321 gccacgacgc tattgacatc gaggcggcta agggcgggag tgtcgtgctc tcgggtgcgt
    19381 tggcggagct cggcaacgat ttccttgatg cggctcgccc cctcggaaat ttcctcgatg
    19441 atcgtcccga cctcgtcgcg tatctccgca tagggaaggt tggcgagctg gaaatctggg
    19501 tcccggcggt actgctcgtc gagcacctcg agagcgtcgc gccaggcgtt tctcaacagc
    19561 ggtgtgttga gggtgatgaa gtgggttggg ttgttgattt cgtgggcgac gctggaaacc
    19621 agggtgccca gggcgatcat cttctctgct tcctggagct ctcgccgctg gcgttcggtt
    19681 tccgcttcga ttctcttgat ctcggtgatg tctcgggagc taccccaaac ccggatgaga
    19741 tgaccgttct cgatgacgcc ggtaaaggag ctcaagagag tgtgtagctg cccattttct
    19801 cgacgcacga aggattcggc actgtgtccg gaatatcccg attccacggc cgcggcgaga
    19861 gcttggcgat tctgaggatc tccgtgtacc agaaattcct ccagagtgag gtggtgaaat
    19921 tcctccaagg attcaaaacc atagagctct agaaaggcgt cgttacactc cgctgtgtag
    19981 gcgtggcgat tgagccaatc gatctgctct tgttttgtca gatgcagcgg cagaggctcg
    20041 gtgagctcca gacgccagat cgcctccaag ctgttggcga cgaaggcccg atagcgctcc
    20101 tcactggccc gcagagccct ttccgcctga tctcgttcac tcaccaccac cgccagcagc
    20161 aatggcagaa cgatggaaac caccaagaag acttgcatca gtagaatgcg ctgatcgatc
    20221 gacgtggcgg ccatggaagc gaagggacca ctcccctggg aggtaaacca cacggctaag
    20281 gaggagacca gcagaccggc cacggagcat ccgaagactc cgaaccgcag agcggcccag
    20341 agcatcaacg ggatcatcaa gaaagcgacg ggacgggcgg attggccgaa gatcagcgtc
    20401 gaagcagccg cgatagccac gatgagggcc cctgcctcga caaggcgccc gagccccttg
    20461 aggcgcgcca aacgccttcg acggtaggtg agaatcaccg gcgagaggat caggatcccg
    20521 agggcgtcag ccccccacca ggtatagaag aacgtccaat gggagttggg ttgaaagatc
    20581 cagctcccga gaatggtggc gacggtggct cccgccaaag gagcgatgac cgctgccagc
    20641 agtccgaatc gcagagtctg ggaggcggtg gaaaggtcga tcagctcggg taggaagcgc
    20701 cgcaggagat agatcccgga ggaggcagtg aacaagctcg gtagggccaa gagcgcagcc
    20761 tcgcctagag cagctccgga caccaaggtg gtggccatgg cgttggcgac caagcagcca
    20821 gcgacgatgg gaggccacaa gggagggcga gtacgaagca gggcgaccag caggattgcg
    20881 ttggctggcc agagagaggc aacgttggtg ggatcgtcgg caagccagca gccaatggcg
    20941 gcgccggcaa agtagagcag actattgacc gtcacgatgg tggcggcccc ccatctgctc
    21001 tcggcggcct tccaggatcc atcgtcagcg agcgtttttc gcgcttttct tggcacgctc
    21061 ccctccttgc tcccctccac gtcctgcccg ctgggcacgt tgcgagcaga tttggaaggg
    21121 agtgattgat gccagacgag agagtctagc agccagggga gatgggaatg ggtcaggtcc
    21181 tcgtttgcat ggggggcgtt acggtctgtc cccggaggaa atccgatacc gcttcgctgg
    21241 acagggggac gcccagcaga aatccttggg ctcggtgaca accgagggcc tccagttgct
    21301 gaagttggtc cacggtttcg accccctcgg caacgaccac catgtcgagc tcctgggcca
    21361 accggacgat gctagccacc acttgggttt ggatcttcga aacgccgagg ccagcaatga
    21421 aggagcggtc gattttcaat gcttcgccgg gaatatagtg caagtagctg aggcaggagt
    21481 agccggtgcc gaagtcatct accaagatgc cgattcccct ctcccgcagg cgacggatgg
    21541 ctcctttgac ctgtggtgat ggctccagcc gcgcccactc ggtgagctcc agtttgaggt
    21601 cccgggcttc cagaccttgg cgaccgaggg cttgctccac ccggaccgga agggtcgagt
    21661 cgagaatctc cggagctgtc aaattggtcg agacccagat ctgatccccg tggctcgatt
    21721 gttgtcgcca agaggccagt tgtcgacagg cttccgtcag cacccattgg tcgatggggg
    21781 agatcagccc catttcgatg gcgatgggaa ggaattctcg agggcacagg gtgcctcgcc
    21841 gaggatgctg ccaacgcaga agtgcctcga aaccgacgag gcggcgctgc ggtagggaga
    21901 agataggctg gaaagcgagg cgaaactgtc gcctttcgag agcctgccgc aactcgtttt
    21961 ccagctggaa ccgcgccacc gcctcgaacc gaagactggg ccggaagatc tccagatggc
    22021 tgccggagtt tttggcatgg tagagagcgg tctcggcgtc gcggaggagg ttctccggtc
    22081 tatcctccga cccctggttg agagccagtc ccatactgat gttgacgaag atctcgttgc
    22141 cggcgaggtg aaaaggcttg gtcagctcgg tgtggatacg gttggccacc cgactggctc
    22201 ggtttgaatc cagaagcccc tctaacagta ccgccaggca gccgcctccc aggcgggcaa
    22261 gggtggaatc agtgggaagt tgtgcttcga ctctctcggt gagggagacc aggaggcggt
    22321 cgccaagctc atgaccgaga gcgtcattga cccctcggaa t
//
