TARA_SAMEA6045687_MAG_00000009 - 14 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

TARA_SAMEA6045687_MAG_00000009-scaffold_1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RRE-containing,RiPP-like	39,338	61,596

TARA_SAMEA6045687_MAG_00000009-scaffold_7

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	betalactone	155,518	177,685

TARA_SAMEA6045687_MAG_00000009-scaffold_10

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	T1PKS	4,512	50,829

TARA_SAMEA6045687_MAG_00000009-scaffold_11

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	NRPS,ladderane	6,283	61,292

TARA_SAMEA6045687_MAG_00000009-scaffold_17

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	T1PKS	53,593	105,337

TARA_SAMEA6045687_MAG_00000009-scaffold_20

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	acyl_amino_acids	8,872	69,687

TARA_SAMEA6045687_MAG_00000009-scaffold_22

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	thiopeptide	37,409	64,711

TARA_SAMEA6045687_MAG_00000009-scaffold_25

Region	Type	From	To	Most similar known cluster		Similarity
Region 25.1	NRPS,transAT-PKS,betalactone	36,569	90,489

TARA_SAMEA6045687_MAG_00000009-scaffold_32

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	NRPS,betalactone	20,065	65,299

TARA_SAMEA6045687_MAG_00000009-scaffold_33

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	NRPS	1	52,963

TARA_SAMEA6045687_MAG_00000009-scaffold_40

Region	Type	From	To	Most similar known cluster		Similarity
Region 40.1	hglE-KS	1	29,267

TARA_SAMEA6045687_MAG_00000009-scaffold_42

Region	Type	From	To	Most similar known cluster		Similarity
Region 42.1	RRE-containing	3,837	24,145

TARA_SAMEA6045687_MAG_00000009-scaffold_46

Region	Type	From	To	Most similar known cluster		Similarity
Region 46.1	phosphonate	1	24,947

TARA_SAMEA6045687_MAG_00000009-scaffold_53

Region	Type	From	To	Most similar known cluster		Similarity
Region 53.1	NRPS	13,700	42,584

Region	Type	From	To	Similarity
Region 1.1	RRE-containing,RiPP-like	39,338	61,596
Region 7.1	betalactone	155,518	177,685
Region 10.1	T1PKS	4,512	50,829
Region 11.1	NRPS,ladderane	6,283	61,292
Region 17.1	T1PKS	53,593	105,337
Region 20.1	acyl_amino_acids	8,872	69,687
Region 22.1	thiopeptide	37,409	64,711
Region 25.1	NRPS,transAT-PKS,betalactone	36,569	90,489
Region 32.1	NRPS,betalactone	20,065	65,299
Region 33.1	NRPS	1	52,963
Region 40.1	hglE-KS	1	29,267
Region 42.1	RRE-containing	3,837	24,145
Region 46.1	phosphonate	1	24,947
Region 53.1	NRPS	13,700	42,584

No secondary metabolite regions were found in these records:: TARA_SAMEA6045687_MAG_00000009-scaffold_2; TARA_SAMEA6045687_MAG_00000009-scaffold_3; TARA_SAMEA6045687_MAG_00000009-scaffold_4; TARA_SAMEA6045687_MAG_00000009-scaffold_5; TARA_SAMEA6045687_MAG_00000009-scaffold_6; TARA_SAMEA6045687_MAG_00000009-scaffold_8; TARA_SAMEA6045687_MAG_00000009-scaffold_9; TARA_SAMEA6045687_MAG_00000009-scaffold_12; TARA_SAMEA6045687_MAG_00000009-scaffold_13; TARA_SAMEA6045687_MAG_00000009-scaffold_14; TARA_SAMEA6045687_MAG_00000009-scaffold_15; TARA_SAMEA6045687_MAG_00000009-scaffold_16; TARA_SAMEA6045687_MAG_00000009-scaffold_18; TARA_SAMEA6045687_MAG_00000009-scaffold_19; TARA_SAMEA6045687_MAG_00000009-scaffold_21; TARA_SAMEA6045687_MAG_00000009-scaffold_23; TARA_SAMEA6045687_MAG_00000009-scaffold_24; TARA_SAMEA6045687_MAG_00000009-scaffold_26; TARA_SAMEA6045687_MAG_00000009-scaffold_27; TARA_SAMEA6045687_MAG_00000009-scaffold_28; TARA_SAMEA6045687_MAG_00000009-scaffold_29; TARA_SAMEA6045687_MAG_00000009-scaffold_30; TARA_SAMEA6045687_MAG_00000009-scaffold_31; TARA_SAMEA6045687_MAG_00000009-scaffold_34; TARA_SAMEA6045687_MAG_00000009-scaffold_35; TARA_SAMEA6045687_MAG_00000009-scaffold_36; TARA_SAMEA6045687_MAG_00000009-scaffold_37; TARA_SAMEA6045687_MAG_00000009-scaffold_38; TARA_SAMEA6045687_MAG_00000009-scaffold_39; TARA_SAMEA6045687_MAG_00000009-scaffold_41; TARA_SAMEA6045687_MAG_00000009-scaffold_43; TARA_SAMEA6045687_MAG_00000009-scaffold_44; TARA_SAMEA6045687_MAG_00000009-scaffold_45; TARA_SAMEA6045687_MAG_00000009-scaffold_47; TARA_SAMEA6045687_MAG_00000009-scaffold_48; TARA_SAMEA6045687_MAG_00000009-scaffold_49; TARA_SAMEA6045687_MAG_00000009-scaffold_50; TARA_SAMEA6045687_MAG_00000009-scaffold_51; TARA_SAMEA6045687_MAG_00000009-scaffold_52; TARA_SAMEA6045687_MAG_00000009-scaffold_54; TARA_SAMEA6045687_MAG_00000009-scaffold_55; TARA_SAMEA6045687_MAG_00000009-scaffold_56; TARA_SAMEA6045687_MAG_00000009-scaffold_57; TARA_SAMEA6045687_MAG_00000009-scaffold_58; TARA_SAMEA6045687_MAG_00000009-scaffold_59; TARA_SAMEA6045687_MAG_00000009-scaffold_60; TARA_SAMEA6045687_MAG_00000009-scaffold_61; TARA_SAMEA6045687_MAG_00000009-scaffold_62; TARA_SAMEA6045687_MAG_00000009-scaffold_63; TARA_SAMEA6045687_MAG_00000009-scaffold_64; TARA_SAMEA6045687_MAG_00000009-scaffold_65; TARA_SAMEA6045687_MAG_00000009-scaffold_66; TARA_SAMEA6045687_MAG_00000009-scaffold_67; TARA_SAMEA6045687_MAG_00000009-scaffold_68; TARA_SAMEA6045687_MAG_00000009-scaffold_69; TARA_SAMEA6045687_MAG_00000009-scaffold_70; TARA_SAMEA6045687_MAG_00000009-scaffold_71; TARA_SAMEA6045687_MAG_00000009-scaffold_72; TARA_SAMEA6045687_MAG_00000009-scaffold_73; TARA_SAMEA6045687_MAG_00000009-scaffold_74; TARA_SAMEA6045687_MAG_00000009-scaffold_75; TARA_SAMEA6045687_MAG_00000009-scaffold_76; TARA_SAMEA6045687_MAG_00000009-scaffold_77; TARA_SAMEA6045687_MAG_00000009-scaffold_78; TARA_SAMEA6045687_MAG_00000009-scaffold_79; TARA_SAMEA6045687_MAG_00000009-scaffold_80; TARA_SAMEA6045687_MAG_00000009-scaffold_81; TARA_SAMEA6045687_MAG_00000009-scaffold_82; TARA_SAMEA6045687_MAG_00000009-scaffold_83; TARA_SAMEA6045687_MAG_00000009-scaffold_84; TARA_SAMEA6045687_MAG_00000009-scaffold_85; TARA_SAMEA6045687_MAG_00000009-scaffold_86; TARA_SAMEA6045687_MAG_00000009-scaffold_87; TARA_SAMEA6045687_MAG_00000009-scaffold_88; TARA_SAMEA6045687_MAG_00000009-scaffold_89; TARA_SAMEA6045687_MAG_00000009-scaffold_90; TARA_SAMEA6045687_MAG_00000009-scaffold_91; TARA_SAMEA6045687_MAG_00000009-scaffold_92; TARA_SAMEA6045687_MAG_00000009-scaffold_93; TARA_SAMEA6045687_MAG_00000009-scaffold_94; TARA_SAMEA6045687_MAG_00000009-scaffold_95; TARA_SAMEA6045687_MAG_00000009-scaffold_96; TARA_SAMEA6045687_MAG_00000009-scaffold_97; TARA_SAMEA6045687_MAG_00000009-scaffold_98; TARA_SAMEA6045687_MAG_00000009-scaffold_99; TARA_SAMEA6045687_MAG_00000009-scaffold_100

Compact view

TARA_SAMEA6045687_MAG_00000009-scaffold_1 - Region 1 - RRE-containing,RiPP-like

Download region GenBank file

Download region SVG

Location: 39,338 - 61,596 nt. (total: 22,259 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

TARA_SAMEA6045687_MAG_00000009-scaffold_7 - Region 1 - betalactone

Download region GenBank file

Download region SVG

Location: 155,518 - 177,685 nt. (total: 22,168 nt) Show pHMM detection rules used

Region on contig edge.

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

TARA_SAMEA6045687_MAG_00000009-scaffold_10 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 4,512 - 50,829 nt. (total: 46,318 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4511 - 50829:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_10_25

PKS_AT (547..842): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 85.7
Methylmalonyl-CoA: 82.2
Malonyl-CoA: 81.9
Isobutyryl-CoA: 70.0
Ethylmalonyl-CoA: 63.4
Propionyl-CoA: 47.6
Benzoyl-CoA: 46.7
2-Methylbutyryl-CoA: 43.0
Acetyl-CoA: 39.7
trans-1,2-CPDA: 33.3
fatty_acid: 23.9
inactive: 22.4
3-Methylbutyryl-CoA: 19.4
CHC-CoA: 15.5

TARA_SAMEA6045687_MAG_00000009-scaffold_11 - Region 1 - NRPS,ladderane

Download region GenBank file

Download region SVG

Location: 6,283 - 61,292 nt. (total: 55,010 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
ladderane: ladderane

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 6282 - 61292:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (leu)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 6282 - 55736:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_11_22

Search NORINE for peptide: strict or relaxed

AMP-binding (20..428): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAWyLafVlK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6045687_MAG_00000009-scaffold_11_23

Search NORINE for peptide: strict or relaxed

CAL_domain (48..479): pk

minowa: NH2

Prediction, score:

NH2: 41.7
fatty_acid: 15.5
Acetyl-CoA: 9.1
shikimic_acid: 0.0
AHBA: 0.0

AMP-binding (1136..1555): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: eAgtMGAVhK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6045687_MAG_00000009-scaffold_11_25

Search NORINE for peptide: strict or relaxed

AMP-binding (8..411): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmAgIGAlcK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 60% (weak)

TARA_SAMEA6045687_MAG_00000009-scaffold_17 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 53,593 - 105,337 nt. (total: 51,745 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

TARA_SAMEA6045687_MAG_00000009-scaffold_20 - Region 1 - acyl_amino_acids

Download region GenBank file

Download region SVG

Location: 8,872 - 69,687 nt. (total: 60,816 nt) Show pHMM detection rules used

acyl_amino_acids: NasY

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

TARA_SAMEA6045687_MAG_00000009-scaffold_22 - Region 1 - thiopeptide

Download region GenBank file

Download region SVG

Location: 37,409 - 64,711 nt. (total: 27,303 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Thiopeptides

Thiopeptide predictions

No core peptides found.

Thiopeptides

Core peptide predictions

No core peptides found.

TARA_SAMEA6045687_MAG_00000009-scaffold_25 - Region 1 - NRPS,betalactone,transAT-PKS

Download region GenBank file

Download region SVG

Location: 36,569 - 90,489 nt. (total: 53,921 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 36568 - 90489:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (cys) + (cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_25_49

Search NORINE for peptide: strict or relaxed

AMP-binding (2386..2787): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_25_50

Search NORINE for peptide: strict or relaxed

AMP-binding (1722..2120): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_25_51

Search NORINE for peptide: strict or relaxed

AMP-binding (1717..2118): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_25_52

Search NORINE for peptide: strict or relaxed

AMP-binding (568..967): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNfSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

TARA_SAMEA6045687_MAG_00000009-scaffold_25_54

Search NORINE for peptide: strict or relaxed

AMP-binding (30..434): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVLCK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_25_55

PKS_AT (206..502): mal

ATSignature: Malonyl-CoA, inactive

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 95.8%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 191.6
inactive: 138.9
Methoxymalonyl-CoA: 65.7
Methylmalonyl-CoA: 56.0
Propionyl-CoA: 43.7
Benzoyl-CoA: 30.7
Isobutyryl-CoA: 29.2
2-Methylbutyryl-CoA: 21.6
Acetyl-CoA: 21.1
Ethylmalonyl-CoA: 19.8
CHC-CoA: 17.6
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

TARA_SAMEA6045687_MAG_00000009-scaffold_32 - Region 1 - NRPS,betalactone

Download region GenBank file

Download region SVG

Location: 20,065 - 65,299 nt. (total: 45,235 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 20064 - 65299:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_32_23

PKS_AT (7..300): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

TARA_SAMEA6045687_MAG_00000009-scaffold_32_29

Search NORINE for peptide: strict or relaxed

AMP-binding (50..449): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aakHSGeViK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 50% (weak)

AMP-binding (1138..1529): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_33 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 1 - 52,963 nt. (total: 52,963 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 52963:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-cys - cys - Me-cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_33_13

Search NORINE for peptide: strict or relaxed

AMP-binding (575..972): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (2042..2447): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (3112..3512): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_33_16

Search NORINE for peptide: strict or relaxed

AMP-binding (537..932): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

TARA_SAMEA6045687_MAG_00000009-scaffold_40 - Region 1 - hglE-KS

Download region GenBank file

Download region SVG

Location: 1 - 29,267 nt. (total: 29,267 nt) Show pHMM detection rules used

Region on contig edge.

hglE-KS: (hglE or hglD)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 29267:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_40_2

PKS_AT (576..878): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 54.5
Methoxymalonyl-CoA: 43.0
inactive: 35.4
Methylmalonyl-CoA: 28.8
fatty_acid: 18.2
Propionyl-CoA: 12.8
2-Methylbutyryl-CoA: 10.8
Isobutyryl-CoA: 7.5
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

TARA_SAMEA6045687_MAG_00000009-scaffold_42 - Region 1 - RRE-containing

Download region GenBank file

Download region SVG

Location: 3,837 - 24,145 nt. (total: 20,309 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

TARA_SAMEA6045687_MAG_00000009-scaffold_46 - Region 1 - phosphonate

Download region GenBank file

Download region SVG

Location: 1 - 24,947 nt. (total: 24,947 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: phosphonates

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

TARA_SAMEA6045687_MAG_00000009-scaffold_53 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 13,700 - 42,584 nt. (total: 28,885 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

Show module domains

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13699 - 42584:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

TARA_SAMEA6045687_MAG_00000009-scaffold_53_30

Search NORINE for peptide: strict or relaxed

AMP-binding (493..887): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAyTIAAVCK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 90% (moderate)