CARD22-1_SAMN24292826_MAG_00000006 - 19 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

CARD22-1_SAMN24292826_MAG_00000006-scaffold_3

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	lanthipeptide-class-v	1	46,837
Region 3.2	hserlactone	67,743	88,363

CARD22-1_SAMN24292826_MAG_00000006-scaffold_6

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	terpene	194,555	219,815

CARD22-1_SAMN24292826_MAG_00000006-scaffold_8

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	phosphonate	1	24,531
Region 8.2	siderophore	27,198	43,725

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	NRPS,T1PKS	144,305	215,759

CARD22-1_SAMN24292826_MAG_00000006-scaffold_10

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	thioamitides	31,379	54,111
Region 10.2	lassopeptide	190,866	204,884

CARD22-1_SAMN24292826_MAG_00000006-scaffold_11

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	terpene	36,402	57,268
Region 11.2	T3PKS	111,790	152,845

CARD22-1_SAMN24292826_MAG_00000006-scaffold_13

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	NRPS	126,387	172,680

CARD22-1_SAMN24292826_MAG_00000006-scaffold_15

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	resorcinol	41,403	83,292

CARD22-1_SAMN24292826_MAG_00000006-scaffold_19

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	phosphonate,NRPS-like	1	69,033

CARD22-1_SAMN24292826_MAG_00000006-scaffold_22

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	arylpolyene	26,547	67,740

CARD22-1_SAMN24292826_MAG_00000006-scaffold_32

Region	Type	From	To	Most similar known cluster		Similarity
Region 32.1	NRPS	3,929	42,490

CARD22-1_SAMN24292826_MAG_00000006-scaffold_35

Region	Type	From	To	Most similar known cluster		Similarity
Region 35.1	phosphonate	808	35,733

CARD22-1_SAMN24292826_MAG_00000006-scaffold_52

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	phosphonate	1	14,661

CARD22-1_SAMN24292826_MAG_00000006-scaffold_53

Region	Type	From	To	Most similar known cluster		Similarity
Region 53.1	thioamitides	1	13,330

CARD22-1_SAMN24292826_MAG_00000006-scaffold_56

Region	Type	From	To	Most similar known cluster		Similarity
Region 56.1	ranthipeptide	1	10,543

Region	Type	From	To	Similarity
Region 3.1	lanthipeptide-class-v	1	46,837
Region 3.2	hserlactone	67,743	88,363
Region 6.1	terpene	194,555	219,815
Region 8.1	phosphonate	1	24,531
Region 8.2	siderophore	27,198	43,725
Region 9.1	NRPS,T1PKS	144,305	215,759
Region 10.1	thioamitides	31,379	54,111
Region 10.2	lassopeptide	190,866	204,884
Region 11.1	terpene	36,402	57,268
Region 11.2	T3PKS	111,790	152,845
Region 13.1	NRPS	126,387	172,680
Region 15.1	resorcinol	41,403	83,292
Region 19.1	phosphonate,NRPS-like	1	69,033
Region 22.1	arylpolyene	26,547	67,740
Region 32.1	NRPS	3,929	42,490
Region 35.1	phosphonate	808	35,733
Region 52.1	phosphonate	1	14,661
Region 53.1	thioamitides	1	13,330
Region 56.1	ranthipeptide	1	10,543

No secondary metabolite regions were found in these records:: CARD22-1_SAMN24292826_MAG_00000006-scaffold_1; CARD22-1_SAMN24292826_MAG_00000006-scaffold_2; CARD22-1_SAMN24292826_MAG_00000006-scaffold_4; CARD22-1_SAMN24292826_MAG_00000006-scaffold_5; CARD22-1_SAMN24292826_MAG_00000006-scaffold_7; CARD22-1_SAMN24292826_MAG_00000006-scaffold_12; CARD22-1_SAMN24292826_MAG_00000006-scaffold_14; CARD22-1_SAMN24292826_MAG_00000006-scaffold_16; CARD22-1_SAMN24292826_MAG_00000006-scaffold_17; CARD22-1_SAMN24292826_MAG_00000006-scaffold_18; CARD22-1_SAMN24292826_MAG_00000006-scaffold_20; CARD22-1_SAMN24292826_MAG_00000006-scaffold_21; CARD22-1_SAMN24292826_MAG_00000006-scaffold_23; CARD22-1_SAMN24292826_MAG_00000006-scaffold_24; CARD22-1_SAMN24292826_MAG_00000006-scaffold_25; CARD22-1_SAMN24292826_MAG_00000006-scaffold_26; CARD22-1_SAMN24292826_MAG_00000006-scaffold_27; CARD22-1_SAMN24292826_MAG_00000006-scaffold_28; CARD22-1_SAMN24292826_MAG_00000006-scaffold_29; CARD22-1_SAMN24292826_MAG_00000006-scaffold_30; CARD22-1_SAMN24292826_MAG_00000006-scaffold_31; CARD22-1_SAMN24292826_MAG_00000006-scaffold_33; CARD22-1_SAMN24292826_MAG_00000006-scaffold_34; CARD22-1_SAMN24292826_MAG_00000006-scaffold_36; CARD22-1_SAMN24292826_MAG_00000006-scaffold_37; CARD22-1_SAMN24292826_MAG_00000006-scaffold_38; CARD22-1_SAMN24292826_MAG_00000006-scaffold_39; CARD22-1_SAMN24292826_MAG_00000006-scaffold_40; CARD22-1_SAMN24292826_MAG_00000006-scaffold_41; CARD22-1_SAMN24292826_MAG_00000006-scaffold_42; CARD22-1_SAMN24292826_MAG_00000006-scaffold_43; CARD22-1_SAMN24292826_MAG_00000006-scaffold_44; CARD22-1_SAMN24292826_MAG_00000006-scaffold_45; CARD22-1_SAMN24292826_MAG_00000006-scaffold_46; CARD22-1_SAMN24292826_MAG_00000006-scaffold_47; CARD22-1_SAMN24292826_MAG_00000006-scaffold_48; CARD22-1_SAMN24292826_MAG_00000006-scaffold_49; CARD22-1_SAMN24292826_MAG_00000006-scaffold_50; CARD22-1_SAMN24292826_MAG_00000006-scaffold_51; CARD22-1_SAMN24292826_MAG_00000006-scaffold_54; CARD22-1_SAMN24292826_MAG_00000006-scaffold_55; CARD22-1_SAMN24292826_MAG_00000006-scaffold_57; CARD22-1_SAMN24292826_MAG_00000006-scaffold_58; CARD22-1_SAMN24292826_MAG_00000006-scaffold_59; CARD22-1_SAMN24292826_MAG_00000006-scaffold_60; CARD22-1_SAMN24292826_MAG_00000006-scaffold_61; CARD22-1_SAMN24292826_MAG_00000006-scaffold_62; CARD22-1_SAMN24292826_MAG_00000006-scaffold_63

Compact view

CARD22-1_SAMN24292826_MAG_00000006-scaffold_3 - Region 1 - lanthipeptide-class-v

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Location: 1 - 46,837 nt. (total: 46,837 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-v: (APH and HopA1)

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Lanthipeptides

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

CARD22-1_SAMN24292826_MAG_00000006-scaffold_3 - Region 2 - hserlactone

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Location: 67,743 - 88,363 nt. (total: 20,621 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_6 - Region 1 - terpene

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Location: 194,555 - 219,815 nt. (total: 25,261 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_8 - Region 1 - phosphonate

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Location: 1 - 24,531 nt. (total: 24,531 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: phosphonates

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_8 - Region 2 - siderophore

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Location: 27,198 - 43,725 nt. (total: 16,528 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_9 - Region 1 - NRPS,T1PKS

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Location: 144,305 - 215,759 nt. (total: 71,455 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 144304 - 215759:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X) + (val) + (X) + (mal) + (cys - NMe-beta-ala) + (mal) + (NMe-beta-ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_153

Search NORINE for peptide: strict or relaxed

AMP-binding (542..951): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNigvVWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 70% (weak)

AMP-binding (1607..1998): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: tyr, bht
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: gDtlsSLADK
Nearest Stachelhaus code:: ala-b
Stachelhaus code match:: 60% (weak)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_154

Search NORINE for peptide: strict or relaxed

AMP-binding (201..596): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAaFyGCVyK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_159

Search NORINE for peptide: strict or relaxed

AMP-binding (1038..1443): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vAiWvsssFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 40% (weak)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_160

PKS_AT (538..820): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 57.6
Methylmalonyl-CoA: 41.6
Methoxymalonyl-CoA: 26.6
2-Methylbutyryl-CoA: 17.7
Ethylmalonyl-CoA: 17.6
Propionyl-CoA: 14.1
inactive: 13.9
CHC-CoA: 12.6
Benzoyl-CoA: 12.5
trans-1,2-CPDA: 7.9
Isobutyryl-CoA: 3.8
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_161

Search NORINE for peptide: strict or relaxed

AMP-binding (515..911): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNvgiIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 70% (weak)

AMP-binding (1620..2005): beta-ala

NRPSPredictor2: beta-ala

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VDAVhSiADK
Nearest Stachelhaus code:: beta-ala
Stachelhaus code match:: 80% (moderate)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_162

PKS_AT (535..820): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 115.7
Methoxymalonyl-CoA: 64.6
Methylmalonyl-CoA: 61.0
Propionyl-CoA: 46.0
CHC-CoA: 38.5
inactive: 28.4
Ethylmalonyl-CoA: 20.9
2-Methylbutyryl-CoA: 19.2
Isobutyryl-CoA: 18.3
trans-1,2-CPDA: 10.5
fatty_acid: 10.1
Acetyl-CoA: 7.8
Benzoyl-CoA: 5.7
3-Methylbutyryl-CoA: 0.0

CARD22-1_SAMN24292826_MAG_00000006-scaffold_9_163

Search NORINE for peptide: strict or relaxed

AMP-binding (491..876): beta-ala

NRPSPredictor2: beta-ala

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VDAVhSiADK
Nearest Stachelhaus code:: beta-ala
Stachelhaus code match:: 80% (moderate)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_10 - Region 1 - thioamitides

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Location: 31,379 - 54,111 nt. (total: 22,733 nt) Show pHMM detection rules used

thioamitides: ((YcaO or TIGR03882) and TfuA)

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_10 - Region 2 - lassopeptide

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Location: 190,866 - 204,884 nt. (total: 14,019 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

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Lasso peptides

Lasso peptide predictions

Lassopeptide(s) for CARD22-1_SAMN24292826_MAG_00000006-scaffold_10_180 - Putative Class II

CARD22-1_SAMN24292826_MAG_00000006-scaffold_10_180 leader / core peptide / cleaved tail: MKSRHVVKKTHLVRLGSVSRLTK - GGRTAPEEFLGEPQQP

Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues

Lasso peptides

Core peptide predictions

CARD22-1_SAMN24292826_MAG_00000006-scaffold_10_180 - Class II: Cleavage pHMM score: 12.30; RODEO score: 25; Monoisotopic mass: 1693.8 Da; Molecular weight: 1694.8 Da; Number of bridges: 0

CARD22-1_SAMN24292826_MAG_00000006-scaffold_11 - Region 1 - terpene

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Location: 36,402 - 57,268 nt. (total: 20,867 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_11 - Region 2 - T3PKS

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Location: 111,790 - 152,845 nt. (total: 41,056 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

CARD22-1_SAMN24292826_MAG_00000006-scaffold_13 - Region 1 - NRPS

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Location: 126,387 - 172,680 nt. (total: 46,294 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 126386 - 172680:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

CARD22-1_SAMN24292826_MAG_00000006-scaffold_13_112

Search NORINE for peptide: strict or relaxed

AMP-binding (20..414): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gLFayanGAK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 50% (weak)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_13_128

Search NORINE for peptide: strict or relaxed

CAL_domain (47..496): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 27.7
shikimic_acid: 0.0
NH2: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1246..1666): X

NRPSPredictor2: asp, asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmAnmGEVaK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_15 - Region 1 - resorcinol

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Location: 41,403 - 83,292 nt. (total: 41,890 nt) Show pHMM detection rules used

resorcinol: DarB

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_19 - Region 1 - NRPS-like,phosphonate

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Location: 1 - 69,033 nt. (total: 69,033 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: phosphonates
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS domains

Detailed domain annotation

Selected features only

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_22 - Region 1 - arylpolyene

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Location: 26,547 - 67,740 nt. (total: 41,194 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_32 - Region 1 - NRPS

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Location: 3,929 - 42,490 nt. (total: 38,562 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

NRPS/PKS modules

Detailed domain annotation

Selected features only

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Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 3928 - 42490:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

CARD22-1_SAMN24292826_MAG_00000006-scaffold_32_23

Search NORINE for peptide: strict or relaxed

AMP-binding (28..449): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFgYcGGlVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

AMP-binding (1216..1643): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmAnlGEVaK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

CARD22-1_SAMN24292826_MAG_00000006-scaffold_35 - Region 1 - phosphonate

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Location: 808 - 35,733 nt. (total: 34,926 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: phosphonates

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_52 - Region 1 - phosphonate

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Location: 1 - 14,661 nt. (total: 14,661 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: phosphonates

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_53 - Region 1 - thioamitides

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Location: 1 - 13,330 nt. (total: 13,330 nt) Show pHMM detection rules used

Region on contig edge.

thioamitides: ((YcaO or TIGR03882) and TfuA)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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CARD22-1_SAMN24292826_MAG_00000006-scaffold_56 - Region 1 - ranthipeptide

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Location: 1 - 10,543 nt. (total: 10,543 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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