# About

#### How to contact us

Feature requests / bug reports should be submitted via the official <a href="https://github.com/motu-tool/mOTUs/issues" target="_blank">Github</a> repository.


#### Citations

If you find mOTUs4 useful in your work, please cite:

:::{card} <a href="https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1004/7889250" target="_blank">The mOTUs online database provides web-accessible genomic context to taxonomic profiling of microbial communities</a>

Dmitrijeva Marija\*, Ruscheweyh Hans-Joachim\*, Feer Lilith, Li Kang, Miravet-Verde Samuel, Sintsova Anna, Mende Daniel R, Zeller Georg, Sunagawa Shinichi\#

Nucleic Acids Research (2024); gkae1004.

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For mOTUs3:

:::{card} <a href="https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-022-01410-z" target="_blank">Reference genome-independent taxonomic profiling of microbiomes with mOTUs3</a>

Ruscheweyh Hans-Joachim\*, Milanese Alessio\*, Paoli Lucas, Karcher Nicolai, Clayssen Quentin, Keller Marisa Isabell, Wirbel Jakob, Bork Peer, Mende Daniel R, Zeller Georg\#, Sunagawa Shinichi\#

Microbiome (2022); 10(1):212.

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For mOTUs2:

:::{card} <a href="https://www.nature.com/articles/s41467-019-08844-4" target="_blank">Microbial abundance, activity and population genomic profiling with mOTUs2</a>

Milanese Alessio*, Mende Daniel R*, Paoli Lucas, Salazar Guillem, Ruscheweyh Hans-Joachim, Cuenca Miguelangel, Hingamp Pascal, Alves Renato, Costea Paul I, Coelho Luis Pedro, Schmidt Thomas SB, Almeida Alexandre, Mitchell Alex L, Finn Rob D, Huerta-Cepas Jaime, Bork Peer, Zeller Georg#, Sunagawa Shinichi#

Nature Communications (2019); 10(1):1014

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For mOTUs1:

:::{card} <a href="https://www.nature.com/articles/nmeth.2693" target="_blank">Metagenomic species profiling using universal phylogenetic marker genes</a>

Sunagawa Shinichi, Mende Daniel R, Zeller Georg, Izquierdo-Carrasco Fernando, Berger Simon A, Kultima Jens Roat, Coelho Luis Pedro,
Arumugam Manimozhiyan, Tap Julien, Nielsen Henrik Bjørn, Rasmussen Simon, Brunak Søren, Pedersen Oluf, Guarner Francisco, de Vos Willem M,
Wang Jun, Li Junhua, Doré Joël, Ehrlich S Dusko, Stamatakis Alexandros, Bork Peer

Nature Methods (2013); 10(12):1196-9.

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#### Protocol

For more information on how to run mOTUs, see:

:::{card} <a href="https://doi.org/10.1002/cpz1.218" target="_blank">mOTUs: Profiling Taxonomic Composition, Transcriptional Activity and Strain Populations of Microbial Communities</a>

Ruscheweyh Hans-Joachim\*, Milanese Alessio\*, Paoli Lucas, Sintsova Anna, Mende Daniel R, Zeller Georg\#, Sunagawa Shinichi\#

Current Protocols (2021); 1(8):e218.

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#### mOTUs1

The codebase of the first version of mOTUs can be found <a href="http://www.bork.embl.de/software/mOTUs1/" target="_blank">here</a>.

#### License

mOTUs is published under the <a href="https://github.com/motu-tool/mOTUs/blob/master/LICENSE" target="_blank">GPL-3.0</a> license.

![](images/logos_motus_website.png)

<img src="_images/Elixir-Europe-logo-1.png" alt="elixir" width="75"/> mOTUs is part of the <a href="https://elixir-europe.org/about-us/who-we-are/nodes/switzerland" target="_blank">ELIXIR-CH Service Delivery Plan</a>.